Results 61 to 70 of about 220,963 (383)
The pharmacological perturbation of brain zinc impairs BDNF-related signaling and the cognitive performances of young mice. [PDF]
Zinc (Zn2+) is a pleiotropic modulator of the neuronal and brain activity. The disruption of intraneuronal Zn2+ levels triggers neurotoxic processes and affects neuronal functioning.
Bomba, Manuela+13 more
core +2 more sources
Antipsychotic-induced parkinsonism is an undesirable reaction from the extrapyramidal system that occurs against the background of taking antipsychotics (AP), more often in patients with schizophrenia.
E. E. Vaiman+3 more
doaj +1 more source
A BDNF sensitive mechanism is involved in the fear memory resulting from the interaction between stress and the retrieval of an established trace [PDF]
The present study investigates the fear memory resulting from the interaction of a stressful experience and the retrieval of an established fear memory trace.
Bustos, Silvia Gabriela+3 more
core +1 more source
Association of BDNF Val66Met Polymorphism and Brain BDNF levels with Major Depression and Suicide [PDF]
ABSTRACTBrain-derived neurotrophic factor (BDNF) is implicated in the pathophysiology of major depressive disorder (MDD) and suicide. Both are partly caused by early life adversity (ELA) and ELA reduces both BDNF protein and gene expression. This study examines the association of BDNF Val66Met polymorphism and brain BDNF levels with depression and ...
Youssef, Mariam M.+10 more
openaire +4 more sources
Background. The role of recently discovered neurospecific peptides in the pathogenesis of acute and progressive neurologic disorders, their neuroprotective features, and possibilities to use them as markers for the course and prognosis of certain ...
George A. Karkashadze+37 more
doaj +1 more source
Effects of environmental enrichment upon ethanol-induced conditioned place preference and pre-frontal BDNF levels in adolescent and adult mice [PDF]
Environmental enrichment (EE) provides a non-pharmacological tool to alter drug-induced reward, yet its effects on ethanol-induced reward remain controversial. We analyzed adolescent vs.
Camarini, Rosana+6 more
core +1 more source
Corticostriatal BDNF and alcohol addiction [PDF]
Growth factors, long studied for their involvement in neuronal development and plasticity, also regulate responses to drugs of abuse, including alcohol. This review details the intricate interaction between the Brain-Derived Neurotrophic Factor (BDNF) and alcohol, and provides evidence to suggest that corticostriatal BDNF signaling acts to keep alcohol
Logrip, Marian L+3 more
openaire +4 more sources
Diverse Functions of Multiple Bdnf Transcripts Driven by Distinct Bdnf Promoters
The gene encoding brain-derived neurotrophic factor (Bdnf) consists of nine non-coding exons driven by unique promoters, leading to the expression of nine Bdnf transcripts that play different roles in various brain regions and physiological stages.
He You, Bai Lu
openaire +3 more sources
Ana Carolina Proença da Fonseca,1,2 Gabriella de Medeiros Abreu,2 Lohanna Palhinha,1 Verônica Marques Zembrzuski,2 Mario Campos Junior,2 João Regis Ivar Carneiro,3 José Firmino Nogueira Neto,4 Fernanda Cristina C Mattos Magno,5
da Fonseca ACP+12 more
doaj