Results 21 to 30 of about 5,002 (186)

Exploring Bioactive Metabolites From Fusarium falciforme and Aspergillus terreus Isolated From Protease-Rich Fruits: Antifungal, Antitrypanosomal, and Enzymatic Inhibitory Activities. [PDF]

Chem Biodivers
Metabolites from fungi isolated from protease rich‐fruits displayed antifungal, antitrypanosomal and enzymatic inhibitory activities. ABSTRACT Fungal secondary metabolites display remarkable chemical diversity and biological potential, with applications in agriculture and pharmaceuticals. This study isolated and characterized bioactive metabolites from
de Oliveira Almeida G, Mazucato VS, Tonani L, von Zeska Kress MR, Barbosa G, Krogh R, Andricopulo AD, Gomes Ferreira LL, Vieira PC.   +8 more
europepmc   +2 more sources

Divergence of Beauvericin Synthase Gene among Fusarium and Trichoderma Species

Journal of Fungi, 2020
Beauvericin (BEA) is a cyclodepsipeptide mycotoxin, showing insecticidal, antibiotic and antimicrobial activities, as well as inducing apoptosis of cancer cell lines.
Monika Urbaniak, Agnieszka Waśkiewicz, Grzegorz Koczyk, Lidia Błaszczyk, Łukasz Stępień   +4 more
doaj   +1 more source

Physicochemical, Pharmacokinetic and Cytotoxicity of the Compounds Isolated from an Endophyte Fusarium oxysporum: In Vitro and In Silico Approaches

Toxins, 2022
The present study was intended to characterize the secondary metabolites of the endophyte Fusarium oxysporum isolated from the plant Aglaonema hookerianum Schott.
Nazia Hoque, Farhana Afroz, Farjana Khatun, Satyajit Roy Rony, Choudhury Mahmood Hasan, Md. Sohel Rana, Md. Hossain Sohrab   +6 more
doaj   +1 more source

The Natural Fungal Metabolite Beauvericin Exerts Anticancer Activity In Vivo: A Pre-Clinical Pilot Study

Toxins, 2017
Recently, in vitro anti-cancer properties of beauvericin, a fungal metabolite were shown in various cancer cell lines. In this study, we assessed the specificity of this effect by comparing beauvericin cytotoxicity in malignant versus non-malignant cells.
Daniela Heilos, Yelko Rodríguez-Carrasco, Bernhard Englinger, Gerald Timelthaler, Sushilla van Schoonhoven, Michael Sulyok, Simon Boecker, Roderich D. Süssmuth, Petra Heffeter, Rosa Lemmens-Gruber, Rita Dornetshuber-Fleiss, Walter Berger   +11 more
doaj   +1 more source

Study on In Vitro Metabolism and In Vivo Pharmacokinetics of Beauvericin

Toxins, 2022
Beauvericin (BEA) is a well-known mycotoxin produced by many fungi, including Beaveria bassiana. The purpose of this study was to evaluate the in vitro distribution and metabolism characteristics as well as the in vivo pharmacokinetic (PK) profile of BEA.
Yu Yuan, Guangpeng Meng, Yuanbo Li, Chunjie Wu   +3 more
doaj   +1 more source

Scientific Opinion on the risks to human and animal health related to the presence of beauvericin and enniatins in food and feed

EFSA Journal, 2014
Beauvericin and enniatins are mycotoxins produced by various Fusarium species. The European Commission asked EFSA for a scientific opinion on the risk to human and animal health related to the presence of beauvericin and enniatins in food and feed.
EFSA Panel on Contaminants in the Food Chain (CONTAM)
doaj   +1 more source

A Novel and Potentially Multifaceted Dehydroascorbate Reductase Increasing the Antioxidant Systems is Induced by Beauvericin in Tomato

Antioxidants, 2020
Dehydroascorbate reductases (DHARs) are important enzymes that reconvert the dehydroascorbic acid (DHA) into ascorbic acid (ASC). They are involved in the plant response to oxidative stress, such as that induced by the mycotoxin beauvericin (BEA). Tomato
Martina Loi, Silvana De Leonardis, Giuseppina Mulè, Antonio F. Logrieco, Costantino Paciolla   +4 more
doaj   +1 more source

The Role of Nitrogen Fertilization on the Occurrence of Regulated, Modified and Emerging Mycotoxins and Fungal Metabolites in Maize Kernels

Toxins, 2022
The European Food Safety Authority is currently evaluating the risks related to the presence of emerging mycotoxins in food and feeds. The aim of this study was to investigate the role of soil fertility, resulting from different nitrogen fertilization ...
Valentina Scarpino, Michael Sulyok, Rudolf Krska, Amedeo Reyneri, Massimo Blandino   +4 more
doaj   +1 more source

Beauvericin, a Bioactive Compound Produced by Fungi: A Short Review

Molecules, 2012
Beauvericin is a cyclic hexadepsipeptide mycotoxin, which has insecticidal, antimicrobial, antiviral and cytotoxic activities. It is a potential agent for pesticides and medicines.
Lijian Xu, Qinggui Wang
doaj   +1 more source

Diversity and Toxigenicity of Fungi that Cause Pineapple Fruitlet Core Rot

Toxins, 2020
The identity of the fungi responsible for fruitlet core rot (FCR) disease in pineapple has been the subject of investigation for some time. This study describes the diversity and toxigenic potential of fungal species causing FCR in La Reunion, an island ...
Bastien Barral, Marc Chillet, Anna Doizy, Maeva Grassi, Laetitia Ragot, Mathieu Léchaudel, Noel Durand, Lindy Joy Rose, Altus Viljoen, Sabine Schorr-Galindo   +9 more
doaj   +1 more source