Results 111 to 120 of about 30,020,506 (258)
, 2023 Beclin 1 is an ubiquitination target of Nedd4 and Beclin 1 ubiquitination is decreased by Ndfip1 siRNA in HEK293T cells.
Eminy H. Y. Lee (15195317) +5 more
core +1 more source
World Journal of Surgical Oncology, 2018 Background The abnormal expression of Beclin-1 has recently been investigated in a variety of tumors. However, previous studies have obtained contradicting results regarding the clinical and prognostic value of Beclin-1 in hepatocellular carcinoma (HCC).
Zhiqiang Qin +5 more
doaj +1 more source
Epirubicin Alters Pancreatic Autophagy and Insulin Synthesis Through a Zinc‐Dependent Mechanism
Journal of Applied Toxicology, EarlyView.ABSTRACT Epirubicin (EPI) can cause metabolic side effects, including chemotherapy‐related diabetes, partly through oxidative stress that disrupts zinc (Zn) homeostasis and impairs autophagy. This study investigated the effects of EPI on Zn regulation and autophagy in the pancreas, as well as the modulatory role of N‐acetylcysteine (NAC). Rats received
Ebru Afşar, Işıl Eranıl
wiley +1 more source
Beclin 1 or not Beclin 1... [PDF]
Autophagy, 2011 Tassula, Proikas-Cezanne +1 more
openaire +2 more sources
Journal of Applied Toxicology, EarlyView.ABSTRACT Bisphenol A (BPA) is a widely used industrial chemical found in polycarbonate plastics and epoxy resins and is recognized for its endocrine‐disrupting properties. Human exposure is common due to its presence in food packaging and everyday products. As BPA use has been restricted, structurally similar compounds such as BPS, BPB, BPAF, and BADGE
Nurbanu Zengin +4 more
wiley +1 more source
, 2018 Jun-Yi Wu,1,* Zhong-Xia Wang,1,* Guang Zhang,1 Xian Lu,1 Guang-Hui Qiang,2 Wei Hu,2 An-Lai Ji,3 Jun-Hua Wu,4 Chun-Ping Jiang1 1Department of Hepatobiliary Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu ...
Zhang G +8 more
core
Regulation of the Autophagic Bcl-2/Beclin 1 Interaction
, 2012 Autophagy is an intracellular degradation process responsible for the delivery of cellular material to the lysosomes. One of the key mechanisms for control of autophagy is the modulation of the interaction between the autophagic protein Beclin 1 and the ...
Jean-Paul Decuypere +2 more
core +1 more source
Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives
JSFA reports, EarlyView.Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz +10 more
wiley +1 more source
Clinicopathological correlation of beclin-1 expression in human colon cancer.
, 2011 464 Background: We investigated the expression of beclin-1 and bcl-2 in human colon cancer tissue by immunohistochemical analysis using a tissue microarray in relation to other prognostic factors.
S. Choi +4 more
core +1 more source
PI3KC3-C1-Beclin 1-C137-S-palmitoylation.pdb
, 2023 In the cryo-EM structure of PI3KC3-C1(EMDB ID:EMD-6785), the sidechain of C137 in Beclin 1 points to a proximal hydrophobic groove mainly formed by F64, Y66, and I76 residues of ATG14L, and W591 residue of VPS15.
Mengmeng Zhang (1507543) +10 more
core +1 more source