Results 121 to 130 of about 46,670 (237)

High Beclin-1 and ARID1A expression corelates with poor survival and high recurrence in intrahepatic cholangiocarcinoma: a histopathological retrospective study

open access: yesBMC Cancer, 2019
Background Although surgical resection provides a cure for patients with intrahepatic cholangiocarcinoma (ICC), the risk of mortality and recurrence remains high.
Chao Bi   +8 more
doaj   +1 more source

Autophagy-deficient breast cancer shows early tumor recurrence and escape from dormancy [PDF]

open access: yes, 2018
Breast cancer patients who initially respond to cancer therapies often succumb to distant recurrence of the disease. It is not clear why people with the same type of breast cancer respond to treatments differently; some escape from dormancy and relapse ...
Manjili, Masoud H.
core   +1 more source

Genotypic Variation and Association Mapping for Plant Stature and Anthesis‐Silking Interval in Set of Temperate‐Adapted Maize Lines Developed by DH and SSD Methods

open access: yesPlant Breeding, EarlyView.
ABSTRACT BS39 is a broad‐based population of tropical maize adapted to temperate environments that can provide useful and unique alleles to US Corn Belt breeding programmes. Doubled‐haploid (DH) has been used as an efficient alternative method to speed up the development of maize lines. Our objectives were to compare genetic parameters for plant height
Gabriela dos Santos Pereira   +6 more
wiley   +1 more source

Spinal cord injury induces upregulation of Beclin 1 and promotes autophagic cell death

open access: yesNeurobiology of Disease, 2009
Autophagy is a degradation of the cytoplasm and it induces autophagic cell death in several neurodegenerative conditions. Beclin 1, a Bcl-2-interacting protein, is known to be a promoter of autophagy.
Haruo Kanno   +3 more
doaj   +1 more source

Obatoclax and Paclitaxel Synergistically Induce Apoptosis and Overcome Paclitaxel Resistance in Urothelial Cancer Cells [PDF]

open access: yes, 2018
Paclitaxel is a treatment option for advanced or metastatic bladder cancer after the failure of first-line cisplatin and gemcitabine, although resistance limits its clinical benefits.
Flores, M. Luz   +7 more
core   +1 more source

Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review

open access: yesPhotochemistry and Photobiology, EarlyView.
Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
Bárbara Evelyn Santos de Lima   +6 more
wiley   +1 more source

Beclin 1

open access: yes, 2012
Fil: Molejon, Maria Ines. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Ciencias Biológicas.
Molejon, Maria Ines   +2 more
openaire   +1 more source

Prognostic and clinicopathological value of Beclin-1 expression in hepatocellular carcinoma: a meta-analysis

open access: yesWorld Journal of Surgical Oncology, 2018
Background The abnormal expression of Beclin-1 has recently been investigated in a variety of tumors. However, previous studies have obtained contradicting results regarding the clinical and prognostic value of Beclin-1 in hepatocellular carcinoma (HCC).
Zhiqiang Qin   +5 more
doaj   +1 more source

Muscle wasting in cancer cachexia: Mechanisms and the role of exercise

open access: yesExperimental Physiology, EarlyView.
Abstract Cancer cachexia (CC) is a multifactorial disease marked by a severe and progressive loss of lean muscle mass and characterized further by inflammation and a negative energy/protein balance, ultimately leading to muscle atrophy and loss of muscle tissue.
Zoe P. Libramento   +2 more
wiley   +1 more source

Graphene oxide nanoribbons induce autophagic vacuoles in neuroblastoma cell lines [PDF]

open access: yes, 2016
Since graphene nanoparticles are attracting increasing interest in relation to medical applications, it is important to understand their potential effects on humans. In the present study, we prepared graphene oxide (GO) nanoribbons by oxidative unzipping
Fico, Flavia   +7 more
core   +2 more sources

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