Results 41 to 50 of about 286,840 (196)

Bulk and single-cell transcriptomic brain data identify overlapping processes and cell-types with human AUD and mammalian models of alcohol use

Translational Psychiatry
This study explores the neurobiological underpinnings of alcohol use disorder (AUD) by integrating bulk and single-cell transcriptomic data from humans, primates, and mice across three brain regions associated with addiction (i.e., prefrontal cortex (PFC)
Spencer B. Huggett, Sharmila Selveraj, John E. McGeary, Ami S. Ikeda, Emerald Yuan, Lauren B. Loeffel, Rohan H. C. Palmer   +6 more
doaj   +1 more source

Exploring the Potential of the Web-Based Virtual World of Second Life to Improve Substance Abuse Treatment Outcomes [PDF]

, 2008
Provides an overview of Second Life, an Internet-based virtual world, and summarizes discussions among addiction recovery experts about integrating virtual reality into behavioral treatment as a way to teach patients new responses to real ...
Andrew Isham, Bret Shaw, David Gustafson, Dick Dillon, James Spartz   +4 more
core  

Clinical psychology of Internet addiction: a review of its conceptualization, prevalence, neuronal processes, and implications for treatment [PDF]

, 2015
Research into Internet addiction (IA) has grown rapidly over the last decade. The topic has generated a great deal of debate, particularly in relation to how IA can be defined conceptually as well as the many methodological limitations.
Griffiths, MD, Kuss, DJ, Pontes, HM
core   +1 more source

Mood changes after watching pornography on the Internet are linked to tendencies towards Internet-pornography-viewing disorder

Addictive Behaviors Reports, 2017
Internet-pornography-viewing disorder (IPD) is considered one type of Internet-use disorder. For IPD's development, it was assumed theoretically that a dysfunctional use of Internet pornography to cope with depressive mood or stress might be considered ...
Christian Laier, Matthias Brand
doaj   +1 more source

Nociceptin attenuates the escalation of oxycodone self-administration by normalizing CeA-GABA transmission in highly addicted rats. [PDF]

, 2020
Approximately 25% of patients who are prescribed opioids for chronic pain misuse them, and 5 to 10% develop an opioid use disorder. Although the neurobiological target of opioids is well known, the molecular mechanisms that are responsible for the ...
Carrette, Lieselot LG, de Guglielmo, Giordano, George, Olivier, Kallupi, Marsida, Kononoff, Jenni, Palmer, Abraham A, Schweitzer, Paul, Solberg Woods, Leah C   +7 more
core  

Are cocaine-seeking “habits” necessary for the development of addiction-like behavior in rats? [PDF]

, 2018
Drug self-administration models of addiction typically require animals to make the same response (e.g., a lever-press or nose-poke) over and over to procure and take drugs.
Fadanelli, Monica, Kawa, Alex B., Robinson, Terry E., Singer, Bryan F.   +3 more
core   +2 more sources

A Systematic Review of Online Sex Addiction and Clinical Treatments Using CONSORT Evaluation [PDF]

, 2015
Researchers have suggested that the advances of the Internet over the past two decades have gradually eliminated traditional offline methods of obtaining sexual material.
A Cooper, A Cooper, A Cooper, A Cooper, A Cooper, A Cooper, A Cooper, A Goodman, A Goodman, American Psychological Association, B Paul, C Grov, C Laier, CC Pratt, Centres for Reviews and Dissemination, CH Lou, DG Altman, DJ Stein, DL Delmonico, DL King, HH Jensen, J Orford, J Popay, J Riemersma, J Sadiza, JL Elmore, JN Hook, JP Schneider, JP Schneider, K Daneback, K Shaughnessy, KL Broad, KM Hertlein, KR McBride, L Arai, M Kaufman, M Rodgers, MD Griffiths, MD Griffiths, MD Griffiths, MF Schwartz, MH Orzack, MH Orzack, MH Orzack, MJ McKelland, MP Kafka, MP Twohig, MS Bhatia, NC Raymond, NM Petry, NS Koch, P Carnes, PJ Carnes, PJ Carnes, PW Schnarrs, R Weiss, S Correll, S Eisen, S Sussman, S Turkle, SA Hardy, SC Boies, SC Kalichman, SR Leiblum, TE Mudry   +64 more
core   +1 more source

Online-specific fear of missing out and Internet-use expectancies contribute to symptoms of Internet-communication disorder

Addictive Behaviors Reports, 2017
Some of the most frequently used online applications are Facebook, WhatsApp, and Twitter. These applications allow individuals to communicate with other users, to share information or pictures, and to stay in contact with friends all over the world ...
Elisa Wegmann, Ursula Oberst, Benjamin Stodt, Matthias Brand   +3 more
doaj   +1 more source

Hippocampal BDNF regulates a shift from flexible, goal-directed to habit memory system function following cocaine abstinence. [PDF]

, 2019
The transition from recreational drug use to addiction involves pathological learning processes that support a persistent shift from flexible, goal-directed to habit behavioral control.
Blurton-Jones, Matthew, Harvey, Eric, Kennedy, Pamela J   +2 more
core   +1 more source

Introduction to Behavioral Addictions [PDF]

The American Journal of Drug and Alcohol Abuse, 2010
Several behaviors, besides psychoactive substance ingestion, produce short-term reward that may engender persistent behavior, despite knowledge of adverse consequences, i.e., diminished control over the behavior. These disorders have historically been conceptualized in several ways. One view posits these disorders as lying along an impulsive-compulsive
Jon E, Grant, Marc N, Potenza, Aviv, Weinstein, David A, Gorelick   +3 more
openaire   +2 more sources