Results 61 to 70 of about 42,152 (307)

Adipose mTORC1 Suppresses Prostaglandin Signaling and Beige Adipogenesis via the CRTC2-COX-2 Pathway

Cell Reports, 2018
Summary: Beige adipocytes are present in white adipose tissue (WAT) and have thermogenic capacity to orchestrate substantial energy metabolism and counteract obesity.
Xing Zhang, Yan Luo, Chunqing Wang, Xiaofeng Ding, Xin Yang, Dandan Wu, Floyd Silva, Zijiang Yang, Qin Zhou, Lu Wang, Xiaoqing Wang, Jianlin Zhou, Nathan Boyd, Michael Spafford, Mark Burge, Xuexian O. Yang, Meilian Liu   +16 more
doaj   +1 more source

Scalable Generation of Pre‐Vascularized and Functional Human Beige Adipose Organoids

Advanced Science, 2023
Obesity and type 2 diabetes are becoming a global sociobiomedical burden. Beige adipocytes are emerging as key inducible actors and putative relevant therapeutic targets for improving metabolic health.
Mélanie Escudero, Laurence Vaysse, Gozde Eke, Marion Peyrou, Francesc Villarroya, Sophie Bonnel, Yannick Jeanson, Louisa Boyer, Christophe Vieu, Benoit Chaput, Xi Yao, Frédéric Deschaseaux, Mélissa Parny, Isabelle Raymond‐Letron, Christian Dani, Audrey Carrière, Laurent Malaquin, Louis Casteilla   +17 more
doaj   +1 more source

Revisiting a long‐overlooked skull: Implications for the distribution of Dinodontosaurus brevirostris (Kannemeyeriiformes) in the Brazilian Triassic

The Anatomical Record, EarlyView.
Abstract Dicynodonts (Anomodontia: Dicynodontia) were one of the main groups of terrestrial tetrapods in Permian and Triassic faunas. In Brazil, the genus Dinodontosaurus is one of the most common tetrapod taxon in the Triassic Santa Maria Supersequence. This genus has a complex taxonomic history and is represented in the Triassic of both Argentina and
Julia Lara Rodrigues de Souza, João Lucas Da Silva, Voltaire D. P. Neto, Arielli Fabrício Machado, Juan A. Escobar, Felipe L. Pinheiro   +5 more
wiley   +1 more source

Making Two out of One: Kinesin Motors Driving Plant Cell Division

Cytoskeleton, EarlyView.
ABSTRACT The Kinesin superfamily of microtubule dependent motors is present in all eukaryotes. Not all of the subfamilies are represented in all kingdoms, and the ones that are do not always show conserved functions. Tight control of the cytoskeleton is essential for proper progression and completion of mitosis and cytokinesis, and key functions are ...
Choy Kriechbaum, Sabine Müller
wiley   +1 more source

Pulmonary surface-active materials in the Chediak-Higashi syndrome.

Journal of Lipid Research, 1978
Beige mice express the Chediak-Higashi syndrome. Large inclusions, identified as abnormal lysosomes, are found in many cells. The inclusions in type II alveolar epithelial cells are enlarged lamellar bodies and they are associated with an increase in ...
J L Prueitt, E Y Chi, D Lagunoff
doaj   +1 more source

A comprehensive embryonic staging series of the turtle Trachemys scripta

Developmental Dynamics, EarlyView.
Abstract Background Turtles hold a unique place in vertebrate evolutionary history, making them critical assets in embryology research. Yet, they remain understudied as potential model organisms in the field. Here, to support experimental manipulations with turtle embryos, we have created a complete normal table of development for comprehensive ...
Christina M. Noravian, Perla G. Rand, Amira Mahomed, Annie Rickard, Oscar D. Juvera, Maria Elena de Bellard, Max Ezin   +6 more
wiley   +1 more source

Oogenesis and germinal bed morphology of the brown anole (A. sagrei)

Developmental Dynamics, EarlyView.
Abstract Background The brown anole is a model species of the genus Anolis, a squamate (encompassing lizards and snakes) group widely studied in evolutionary, behavioral, and developmental biology. Full genome annotation, the establishment of gene editing techniques, and comprehensive description of reproductive tract morphology and embryogenesis in ...
Bonnie K. Kircher, Antonia Weberling, Erin J. Vance, Natalia A. Shylo, Katherine Starr, Zoe B. Griffin, Hannah Wilson, Melainia McClain, Florian Hollfelder, Suzannah A. Williams, Thomas J. Sanger, Richard R. Behringer, Paul A. Trainor   +12 more
wiley   +1 more source

Nicotine induces a dual effect on the beige-like phenotype in adipocytes [PDF]

Archives of Biological Sciences, 2019
Nicotine, the main component of cigarette smoke, affects white/brown adipocytes. Few studies have concentrated on beige adipocytes. In this study, 3T3-L1 cells were differentiated in the presence of nicotine (25, 50 and 100 μmol/L) during early ...
Chen Hui-Jian, Xiang Jie, Zhang Wan-Xia, Sun Ao, Li Gai-Ling, Yan You-e   +5 more
doaj   +1 more source

Co‐Occurring Weight‐ and/or Shape‐Motivated Restriction in 5747 Adults With Probable Avoidant/Restrictive Food Intake Disorder

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective According to DSM‐5‐TR, avoidant/restrictive food intake disorder (ARFID) cannot be diagnosed alongside anorexia nervosa (AN), bulimia nervosa (BN), or any other body image disturbance. This does not accurately reflect real‐world symptomatology and recent research, indicating the potential need to revise DSM‐5‐TR Criteria.
Liv Hog, Casey M. MacDermod, Jennifer P. White, Jessica H. Baker, Jerry Guintivano, Jessica S. Johnson, Shelby N. Ortiz, Emily M. Pisetsky, Nadia Micali, Cynthia M. Bulik, Laura M. Thornton, Lisa Dinkler   +11 more
wiley   +1 more source

Distinct cellular and molecular mechanisms for β3 adrenergic receptor-induced beige adipocyte formation

eLife, 2017
Beige/brite adipocytes are induced within white adipose tissues (WAT) and, when activated, consume glucose and fatty acids to produce heat. Classically, two stimuli have been used to trigger a beiging response: cold temperatures and β3-adrenergic ...
Yuwei Jiang, Daniel C Berry, Jonathan M Graff   +2 more
doaj   +1 more source