Results 41 to 50 of about 57,297 (209)
Frontiers in EndocrinologyBackgroundThermogenic beige adipocytes, which dissipate energy as heat, are found in neonates and adults. Recent studies show that neonatal beige adipocytes are highly plastic and contribute to >50% of beige adipocytes in adults.
Raja Gopal Reddy Mooli +12 more
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Stepping Up Human Beige Fat Cell Production
Cell Reports, 2018 Beige fat cells hold significant promise for reducing obesity and metabolic disease. Su et al. (2018) present a robust method to produce human beige adipocytes from pluripotent stem cells via the generation of an expandable intermediary population of ...
Wenli Yang, Patrick Seale
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Thermogenic adipose tissue in energy regulation and metabolic health
Frontiers in Endocrinology, 2023 The ability to generate thermogenic fat could be a targeted therapy to thwart obesity and improve metabolic health. Brown and beige adipocytes are two types of thermogenic fat cells that regulate energy balance. Both adipocytes share common morphological,
Siwen Xue, Derek Lee, Daniel C. Berry
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Frontiers in Bioengineering and Biotechnology, 2022 Excess and dysfunctional adipose tissue plays an important role in metabolic diseases, including obesity, atherosclerosis and type 2 diabetes mellitus. In mammals, adipose tissue is categorized into two types: white and brown.
Yufei He +6 more
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Scientific Reports, 2022 Beige and brown fat consume glucose and lipids to produce heat, using uncoupling protein 1 (UCP1). It is thought that full activation of brown adipose tissue (BAT) may increase total daily energy expenditure by 20%.
Mojgan Nazari +10 more
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Bioengineering Beige Adipose Tissue Therapeutics [PDF]
Frontiers in Endocrinology, 2015 Unlocking the therapeutic potential of brown/beige adipose tissue requires technological advancements that enable the controlled expansion of this uniquely thermogenic tissue. Transplantation of brown fat in small animal model systems has confirmed the expectation that brown fat expansion could possibly provide a novel therapeutic to combat obesity and
Tharp, Kevin M., Stahl, Andreas
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Adipose mTORC1 Suppresses Prostaglandin Signaling and Beige Adipogenesis via the CRTC2-COX-2 Pathway
Cell Reports, 2018 Summary: Beige adipocytes are present in white adipose tissue (WAT) and have thermogenic capacity to orchestrate substantial energy metabolism and counteract obesity.
Xing Zhang +16 more
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Scalable Generation of Pre‐Vascularized and Functional Human Beige Adipose Organoids
Advanced Science, 2023 Obesity and type 2 diabetes are becoming a global sociobiomedical burden. Beige adipocytes are emerging as key inducible actors and putative relevant therapeutic targets for improving metabolic health.
Mélanie Escudero +17 more
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Preliminary OSL studies on beige sepiolites [PDF]
Radiation Protection Dosimetry, 2008 Radiation-induced luminescence signals in beige sepiolite samples were investigated using optically stimulated luminescence. A thermally stable, light-sensitive radiation-induced signal was detected, and radiation dose response and thermal properties of this signal were studied.
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