Results 31 to 40 of about 57,297 (209)
Nature Communications, 2023 Thermogenic beige fat can reduce fat mass and improve metabolic health, yet the ability to form beige fat rapidly declines with age. Here, the authors show that targeting the age-related ramping of Pdgfrβ signalling restores the ageing adipose tissue ...
Abigail M. Benvie +5 more
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Cell Reports, 2018 Summary: Molecular- and cellular-based therapies have the potential to reduce obesity-associated disease. In response to cold, beige adipocytes form in subcutaneous white adipose tissue and convert energy stored in metabolic substrates to heat, making ...
Su Su +14 more
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A Method to Induce Brown/Beige Adipocyte Differentiation from Murine Preadipocytes
Bio-Protocol, 2021 Adipocytes exhibit different morphological and functional characteristics, depending on their anatomical location, developmental origin, and stimulus. While white adipocytes tend to accumulate energy as triglycerides, brown and beige adipocytes tend to ...
Andréa Rocha +3 more
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Beige Fat, Adaptive Thermogenesis, and Its Regulation by Exercise and Thyroid Hormone
Biology, 2019 While it is now understood that the proper expansion of adipose tissue is critically important for metabolic homeostasis, it is also appreciated that adipose tissues perform far more functions than simply maintaining energy balance.
Kevin J. Phillips
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Imaging adipose tissue browning using the TSPO-18kDa tracer [18F]FEPPA
Molecular Metabolism, 2019 Objectives: The browning of white adipose tissue (WAT) into beige has been proposed as a strategy to enhance energy expenditure to combat the growing epidemic of obesity.
S.V. Hartimath +8 more
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Dopaminergic Hyperactivity Accompanied by Hyperlocomotion in C57BL/6J-bgJ/bgJ (beige-J) Mice
Journal of Pharmacological Sciences, 2014 .: Genetic factors affect locomotor activity, which mainly depends on the activation of dopaminergic systems. C57BL/6J-bgJbgJ (beige-J) mice, which exhibit deficiencies in immunological function, show behavioral hyperactivity.
Tomohisa Mori +5 more
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Participation of macrophages in atherosclerotic lesion morphology in LDLr−/− mice
Journal of Lipid Research, 2004 Lystbeige (beige) mice crossed with LDL receptor-deficient (LDLr−/−) mice had a distinct atherosclerotic lesion morphology that was not observed in LDLr−/− mice. This morphology is often associated with a stable plaque phenotype.
Natalie K. Schiller +4 more
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Human BAT possesses molecular signatures that resemble beige/brite cells. [PDF]
PLoS ONE, 2012 Brown adipose tissue (BAT) dissipates chemical energy and generates heat to protect animals from cold and obesity. Rodents possess two types of UCP-1 positive brown adipocytes arising from distinct developmental lineages: "classical" brown adipocytes ...
Louis Z Sharp +10 more
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Frontiers in Endocrinology, 2023 Brown adipose tissue (BAT), a thermoregulatory organ known to promote energy expenditure, has been extensively studied as a potential avenue to combat obesity.
Khanyisani Ziqubu +9 more
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