Neonatal intake of Omega-3 fatty acids enhances lipid oxidation in adipocyte precursors
Summary: Establishing metabolic programming begins during fetal and postnatal development, and early-life lipid exposures play a critical role during neonatal adipogenesis. We define how neonatal consumption of a low omega-6 to −3 fatty acid ratio (n6/n3
Rohan Varshney +14 more
doaj +1 more source
Brown adipocytes can display a mammary basal myoepithelial cell phenotype in vivo [PDF]
This work was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB13030000) and the CAS-Novonordisk Foundation, as well as grants from the ‘1000 talents’ recruitment program, and a ‘Great-wall professorship’ from ...
Jin, Wanzhu +8 more
core +10 more sources
Adipocyte HDAC4 activation leads to beige adipocyte expansion and reduced adiposity. [PDF]
Numerous studies have suggested that beige adipocyte abundance is correlated with improved metabolic performance, but direct evidence showing that beige adipocyte expansion protects animals from the development of obesity is missing. Previously, we have described that the liver kinase b1 (LKB1) regulates beige adipocyte renaissance in subcutaneous ...
Paulo E +4 more
europepmc +6 more sources
Towards a Better Understanding of Beige Adipocyte Plasticity. [PDF]
Beige adipocytes are defined as Ucp1+, multilocular adipocytes within white adipose tissue (WAT) that are capable of thermogenesis, the process of heat generation. In both mouse models and humans, the increase of beige adipocyte population, also called WAT browning, is associated with certain metabolic benefits, such as reduced obesity and increased ...
Paulo E, Wang B.
europepmc +4 more sources
Mitochondria in White, Brown, and Beige Adipocytes [PDF]
Mitochondria play a key role in energy metabolism in many tissues, including cardiac and skeletal muscle, brain, liver, and adipose tissue. Three types of adipose depots can be identified in mammals, commonly classified according to their colour appearance: the white (WAT), the brown (BAT), and the beige/brite/brown‐like (bAT) adipose tissues.
Miroslava Cedikova +7 more
openaire +3 more sources
Excess and dysfunctional adipose tissue plays an important role in metabolic diseases, including obesity, atherosclerosis and type 2 diabetes mellitus. In mammals, adipose tissue is categorized into two types: white and brown.
Yufei He +6 more
doaj +1 more source
Beige adipocytes contribute to breast cancer progression
Adipocytes are the main stromal cells in the mammary microenvironment, and crosstalk between adipocytes and breast cancer cells may play a critical and important role in cancer maintenance and progression. Tumor‑induced differentiation to beige/brown adipose tissue is an important contribution to the hypermetabolic state of breast cancer.
Gantov, Mariana +6 more
openaire +4 more sources
An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling [PDF]
Heejin Jun, Jianke Gong, Eric Perkey
exaly +2 more sources
A Synergistic Antiobesity Effect by a Combination of Capsinoids and Cold Temperature Through Promoting Beige Adipocyte Biogenesis. [PDF]
Beige adipocytes emerge postnatally within the white adipose tissue in response to certain environmental cues, such as chronic cold exposure. Because of its highly recruitable nature and relevance to adult humans, beige adipocytes have gained much ...
Bannai, Makoto +5 more
core +2 more sources
Aquaglyceroporins Are Differentially Expressed in Beige and White Adipocytes [PDF]
Browning of white adipocytes has been proposed as a powerful strategy to overcome metabolic complications, since brown adipocytes are more catabolic, expending energy as a heat form. However, the biological pathways involved in the browning process are still unclear.
Inês Vieira da Silva +5 more
openaire +3 more sources

