Results 131 to 140 of about 15,100 (167)
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Inducible brown/beige adipocytes in retro-orbital adipose tissues
Experimental Eye Research, 2019Beige adipocytes and brown adipocytes can generate heat by using mitochondrial uncoupling protein 1 (Ucp1), a thermogenic protein. Browning/beiging is the emergence of beige adipocytes in white adipose tissues (WAT) for cold acclimatization. Here we show the existence of brown/beige adipocytes in retro-orbital WAT in mice. Histologically, Ucp1-positive
Makoto, Sugiyama +6 more
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Aging of Brown and Beige/Brite Adipose Tissue
2018Brown adipose tissue aging and the concomitant loss of thermogenic capacity have been linked to an inability to maintain normal energy homeostasis in late life. Similarly, the ability of white fat to convert into brite/beige adipose tissue declines. This may ultimately exacerbate the progression of age-related metabolic pathologies, such as insulin ...
Antonia, Graja +2 more
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Regulatory T cells promote adipocyte beiging in subcutaneous adipose tissue
The FASEB Journal, 2020Abstract Regulatory T cells (Tregs) play essential roles in obesity and diabetes. Here, we report a role of Tregs in enhancing β3‐adrenergic receptor agonist CL316243 (CL)‐stimulated thermogenic program in subcutaneous adipose tissue (SAT), but not in visceral fat.
Wenqian, Fang +5 more
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Transcriptome profile of white, brown and beige adipose tissue
The FASEB Journal, 2022Adipose tissue dysregulation lies at the core metabolic syndrome. White adipose tissue (WAT) has the capacity to store energy, whereas brown adipose tissue (BAT) can dissipate energy through thermogenesis. Newly discovered beige adipocytes are brown like adipocytes recruited in WAT in response to b3‐adrenergic stimulation (CL316 ...
Henry Paz +4 more
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Brown and Beige Adipose Tissues in Health and Disease
Comprehensive Physiology, 2017ABSTRACTBrown and beige adipocytes arise from distinct developmental origins. Brown adipose tissue (BAT) develops embryonically from precursors that also give to skeletal muscle. Beige fat develops postnatally and is highly inducible. Beige fat recruitment is mediated by multiple mechanisms, including de novo beige adipogenesis and white‐to‐brown ...
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ADIPOGENESIS FEATURES OF WHITE, BEIGE AND BROWN ADIPOSE TISSUES
BIOTECHNOLOGY: STATE OF THE ART AND PERSPECTIVES, 2021White and brown adipose tissue is present in the human body and is well described. As well as the effect of the type of fat on human health, in particular obesity, type 2 diabetes, insulin tolerance. The presence and distribution of different types of fat in pigs has not been adequately described.
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Dynamic contrast‐enhanced MRI of brown and beige adipose tissues
Magnetic Resonance in Medicine, 2019PurposeThe vascular blood flow in brown adipose tissue (BAT) is important for handling triglyceride clearance, increased blood flow and oxygenation. We used dynamic contrast‐enhanced (DCE)‐MRI and fat fraction (FF) imaging for investigating vascular perfusion kinetics in brown and beige adipose tissues with cold exposure or treatment with β3‐adrenergic
Jadegoud Yaligar +8 more
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Tamoxifen-Prefabricated Beige Adipose Tissue Improves Fat Graft Survival in Mice
Plastic & Reconstructive Surgery, 2018Background: Fat grafting has become an important tool for breast reconstruction in breast cancer patients. Tamoxifen, the hormone therapy agent most frequently used for breast cancer, can affect adipose metabolism and cause browning of adipose tissue.
Junrong, Cai +6 more
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The role of autophagy in brown and beige adipose tissue plasticity
Journal of Physiology and Biochemistry, 2019Since the rediscovery of active brown and beige adipose tissues in humans a decade ago, great efforts have been made to identify the mechanisms underlying the activation and inactivation of these tissues, with the hope of designing potential strategies to fight against obesity and associated metabolic disorders such as type 2 diabetes.
Montserrat Cairó, Joan Villarroya
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Parkin-mediated mitophagy in beige adipose tissue
Metabolism, 2020Zihang, Wang +2 more
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