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Aging of Brown and Beige/Brite Adipose Tissue
2018Brown adipose tissue aging and the concomitant loss of thermogenic capacity have been linked to an inability to maintain normal energy homeostasis in late life. Similarly, the ability of white fat to convert into brite/beige adipose tissue declines. This may ultimately exacerbate the progression of age-related metabolic pathologies, such as insulin ...
Antonia, Graja +2 more
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Transcriptome profile of white, brown and beige adipose tissue
The FASEB Journal, 2022Adipose tissue dysregulation lies at the core metabolic syndrome. White adipose tissue (WAT) has the capacity to store energy, whereas brown adipose tissue (BAT) can dissipate energy through thermogenesis. Newly discovered beige adipocytes are brown like adipocytes recruited in WAT in response to b3‐adrenergic stimulation (CL316 ...
Henry Paz +4 more
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Brown and Beige Adipose Tissues in Health and Disease
Comprehensive Physiology, 2017ABSTRACT Brown and beige adipocytes arise from distinct developmental origins. Brown adipose tissue (BAT) develops embryonically from precursors that also give to skeletal muscle. Beige fat develops postnatally and is highly inducible. Beige fat recruitment is mediated by multiple mechanisms, including
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2017
The recent discovery of functional brown adipose tissue (BAT) in adults has stimulated intense interest for its therapeutic potential against obesity and its related metabolic conditions. Although rodent studies support the importance of brown and beige adipocytes in metabolic health, a smaller number of clinical investigations have examined their ...
Maria Chondronikola, Labros S. Sidossis
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The recent discovery of functional brown adipose tissue (BAT) in adults has stimulated intense interest for its therapeutic potential against obesity and its related metabolic conditions. Although rodent studies support the importance of brown and beige adipocytes in metabolic health, a smaller number of clinical investigations have examined their ...
Maria Chondronikola, Labros S. Sidossis
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Inducible brown/beige adipocytes in retro-orbital adipose tissues
Experimental Eye Research, 2019Beige adipocytes and brown adipocytes can generate heat by using mitochondrial uncoupling protein 1 (Ucp1), a thermogenic protein. Browning/beiging is the emergence of beige adipocytes in white adipose tissues (WAT) for cold acclimatization. Here we show the existence of brown/beige adipocytes in retro-orbital WAT in mice. Histologically, Ucp1-positive
Makoto, Sugiyama +6 more
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Dynamic contrast‐enhanced MRI of brown and beige adipose tissues
Magnetic Resonance in Medicine, 2019PurposeThe vascular blood flow in brown adipose tissue (BAT) is important for handling triglyceride clearance, increased blood flow and oxygenation. We used dynamic contrast‐enhanced (DCE)‐MRI and fat fraction (FF) imaging for investigating vascular perfusion kinetics in brown and beige adipose tissues with cold exposure or treatment with β3‐adrenergic
Jadegoud Yaligar +8 more
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ADIPOGENESIS FEATURES OF WHITE, BEIGE AND BROWN ADIPOSE TISSUES
BIOTECHNOLOGY: STATE OF THE ART AND PERSPECTIVES, 2021White and brown adipose tissue is present in the human body and is well described. As well as the effect of the type of fat on human health, in particular obesity, type 2 diabetes, insulin tolerance. The presence and distribution of different types of fat in pigs has not been adequately described.
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Characterization of the central neural projections to brown, white, and beige adipose tissue
The FASEB Journal, 2017The functional recruitment of classic brown adipose tissue (BAT) and inducible brown‐like or beige fat is, to a large extent, dependent on intact sympathetic neural input. Whereas the central neural circuits directed specifically to BAT or white adipose tissue (WAT) are well established, there is only a developing insight into the ...
Nicole M, Wiedmann +2 more
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Parkin-mediated mitophagy in beige adipose tissue
Metabolism, 2020Zihang, Wang +2 more
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Beige Adipocyte as the Flame of White Adipose Tissue: Regulation of Browning and Impact of Obesity
Journal of Clinical Endocrinology and Metabolism, 2022Alev Eroglu Altinova
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