Results 111 to 120 of about 1,797,962 (199)
Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8329-8336, September 2026.ABSTRACT Introduction and Objective Treatment with sodium‐glucose cotransporter‐2 inhibitors (SGLT‐2i) reduces the risk of both cardiovascular and renal outcomes in type 2 diabetes (T2D). The specific mechanism by which this happens has not yet been clarified.
Shawn Gugliandolo +18 more
wiley +1 more source
Pathology International, Volume 76, Issue 9, September 2026.Adipocytes regulate tumor development and progression through both local and systemic mechanisms. Local regulation involves cancer‐associated adipocytes, paracrine signaling, lipid transfer, and modulation of stromal and immune cells, whereas adipokines, inflammatory cytokines, extracellular vesicles, and lipid transfer mediate systemic regulation ...
Shinya Sato
wiley +1 more source
Leptin, Adiponectin, and Other Adipokines in Regulation of Adipose Tissue Angiogenesis
, 2013 Adipose tissue plays an important endocrine role through the production of secreted factors, termed adipokines. These include hormones such as leptin, adiponectin, resistin, omentin, apelin, and vaspin; classical cytokines such as tumor necrosis factor-α,
Cao, Y, +3 more
core +1 more source
The PPARy ligand rosiglitazone influences triacylglycerol metabolism in non-obese males, without increasing the transcriptional activity of PPARy in the subcutaneous adipose tissue [PDF]
, 2008 PPAR¿ is obligatory for fat mass generation and is thought to determine the amount of TAG stored per fat cell. We investigated whether ligand availability for PPAR¿ is rate limiting in fat mass generation and substrate metabolism.
Kersten, A.H. +3 more
core +1 more source
The FASEB Journal, Volume 40, Issue 15, 15 August 2026.Cultured white adipocytes exposed to 31°C undergo cell‐autonomous metabolic adaptation characterized by enhanced mitochondrial function and widespread remodeling of the mitochondrial acetylome. Acetyl‐proteomic and metabolomic profiling identified mitochondria‐associated proteins, including SHMT2 and PCCA, whose acetylation changes were linked to ...
Hiroyuki Mori +11 more
wiley +1 more source
Adipose Angiogenesis Models in Animals and Methodology
, 2013 Adipose tissue angiogenesis plays a crucial role in the organism as blood vessels are required to supply nutrients and oxygen to the adipose tissue and to remove metabolic waste products.
Honek, J +5 more
core +1 more source
An epigenome atlas of mouse adipocytes
Molecular MetabolismObjective: Epigenetic modifications including histone post translational modifications can influence gene expression in adipocytes, potentially contributing to metabolic dysfunctions, obesity, and insulin resistance.
Laura C. Hinte +4 more
doaj +1 more source
Activation of estrogen receptor alpha induces beiging of adipocytes
Molecular Metabolism, 2018 Objectives: Brown adipose tissue (BAT) and BAT-like adipose tissues, referred to as ‘beige’ adipose tissues uncouple respiration from ATP synthesis via uncoupling protein one (UCP-1).
Roberta S. Santos +5 more
doaj +1 more source
Brown/Beige Adipose Tissue: Novel Players in the Fight Against Obesity
, 2022 Obesity is a metabolic disease which its prevalence is increasing worldwide. Multidisciplinary strategiesare required to combat obesity. Many methods, from diet to surgery, are tried in obesity treatment.However, these methods have not been successful ...
Bagci, Gökhan
core +1 more source
Distinct regulation of hypothalamic and brown/beige adipose tissue activities in human obesity
, 2015 Background/Objectives:The identification of brown/beige adipose tissue in adult humans has motivated the search for methods aimed at increasing its thermogenic activity as an approach to treat obesity.
E. Chaim +17 more
core +1 more source