Solution-phase synthesis of pyrrole-imidazole polyamides [PDF]
Pyrrole−imidazole polyamides are DNA-binding molecules that are programmable for a large repertoire of DNA sequences. Typical syntheses of this class of heterocyclic oligomers rely on solid-phase methods. Solid-phase methodologies offer rapid assembly on
Chenoweth, David M. +2 more
core +3 more sources
Radiofrequency amplification by stimulated emission of radiation (RASER) of solutes was achieved via parahydrogen‐induced polarization (PHIP) and polarization transfer from the produced hyperpolarization donors to solutes via the intermolecular nuclear Overhauser effect (NOE).
Ivan A. Trofimov +8 more
wiley +2 more sources
The 10–23 DNAzyme in Biosensing and Diagnostics: Applications, Challenges, and Future Directions
This review focuses on the 10–23 DNAzyme in diagnostics, spanning unregulated and regulated target‐recognition modes, and their functionalization across colorimetric, fluorescent, electrochemical, electrochemiluminescent, and intracellular biosensing strategies.
Connor Nurmi +5 more
wiley +2 more sources
Discovery and validation of an NMR-based metabolomic profile in urine as TB biomarker
Despite efforts to improve tuberculosis (TB) detection, limitations in access, quality and timeliness of diagnostic services in low- and middle-income countries are challenging for current TB diagnostics.
José Luis Izquierdo-Garcia +21 more
doaj +1 more source
Functional group resolved NMR relaxation of 3-carbon adsorbates in mesoporous alumina
NMR relaxation analysis provides a unique and non-invasive probe of fluid dynamics within porous materials, and may be applied to the interpretation of a wide variety of material and interfacial characteristics.
Neil Robinson +2 more
doaj +1 more source
Water and oil signal assignment in low-moisture mozzarella as determined by time-domain NMR T2 relaxometry [PDF]
A time-domain H-1 nuclear magnetic resonance relaxometry method was elaborated for the rapid microstructural characterization of mozzarella cheese. For this purpose, there is a strong need to know how the experimentally determined T-2 relaxation time ...
Declerck, Arnout +4 more
core +2 more sources
Reaction Monitoring Using SABRE-Hyperpolarized Benchtop (1 T) NMR Spectroscopy [PDF]
The conversion of [IrCl(COD)(IMes)] (COD = cis, cis-1,5-cyclooctadiene, IMes = 1,3-bis(2,4,6-trimethyl-phenyl)imidazole-2-ylidene) in the presence of an excess of para-hydrogen ( p-H2) and a substrate (4-aminopyridine (4-AP) or 4-methylpyridine (4-MP)) into [Ir(H)2(IMes)(substrate)3]Cl is monitored by 1H NMR spectroscopy using a benchtop (1 T ...
Semenova, Olga +5 more
openaire +6 more sources
Natural gas is an essential energy source for a large variety of applications in today’s society. Forecasts predict that it will also play a vital role in decarbonizing the energy sector.
Anton Duchowny +9 more
doaj +1 more source
Synthesis and late-stage functionalization of complex molecules through C-H fluorination and nucleophilic aromatic substitution. [PDF]
We report the late-stage functionalization of multisubstituted pyridines and diazines at the position α to nitrogen. By this process, a series of functional groups and substituents bound to the ring through nitrogen, oxygen, sulfur, or carbon are ...
Fier, Patrick S, Hartwig, John F
core +3 more sources
A handheld high-sensitivity micro-NMR CMOS platform with B-field stabilization for multi-type biological/chemical assays [PDF]
We report a micro-nuclear magnetic resonance (NMR) system compatible with multi-type biological/chemical lab-on-a-chip assays. Unified in a handheld scale (dimension: 14 x 6 x 11 cm³, weight: 1.4 kg), the system is capable to detect<100 pM of ...
Heidari, Hadi +5 more
core +1 more source

