Results 91 to 100 of about 6,317 (201)

Real‐Life Indirect Case Matched Comparison of Dupilumab and Tezepelumab on Airway Oscillometry

Allergy, Volume 81, Issue 1, Page 260-262, January 2026.
Robert Greig, Rory Chan, Brian Lipworth
wiley   +1 more source

Long-Term Eosinophil Depletion: A Real-World Perspective on the Safety and Durability of Benralizumab Treatment in Severe Eosinophilic Asthma [PDF]

: Background/Objectives: Benralizumab is an anti-IL-5 receptor alpha monoclonal antibody that induces the near-complete depletion of eosinophils. This study aimed to evaluate the long-term safety and effectiveness of benralizumab in patients with ...
Beghè, Bianca, Benoni, Roberto, Bonato, Matteo, Bortoli, Michela, Bosi, Annamaria, Caminati, Marco, Casoni, Gianluca, Cavenaghi, Massimiliano, D'Alba, Giuseppina, Diamandi, Adela, Idotta, Giuseppe, Marchi, Mariarita, Mastrototaro, Andrea, Menzella, Francesco, Micheletto, Claudio, Michieletto, Lucio, Muzzolon, Rodolfo, Nalin, Mara, Nizzetto, Manuele, Pini, Laura, Romagnoli, Micaela, Senna, Gianenrico   +21 more
core   +1 more source

Mepolizumab versus benralizumab for eosinophilic granulomatosis with polyangiitis (EGPA): A European real-life retrospective comparative study [PDF]

Background: Following the results of the MANDARA trial, this real-life study aimed at comparing the effectiveness and safety profile of mepolizumab versus benralizumab in a European EGPA cohort.
Baldini C, Berti A, Bettiol A, Bianchi FC, Cameli P, Caminati M, Cathébras P, Cinetto F, Cohen Tervaert JW, Coppola A, Costanzo G, Cottin V, Crimi C, Del Giacco S, Desaintjean C, Egan A, Emmi G, Espigol-Frigolé G, European EGPA Study Group., Folci M, Fornaro M, Franceschini F, Govoni M, Groh M, Guarnieri G, Hellmich B, Iannone F, Jayne D, Jones R, Kernder A, Lo Gullo A, Lombardi C, Lopalco G, Losappio L, Marchi MR, Marvisi C, Mattioli I, Maule M, Mohammad AJ, Moi L, Monti S, Moosig F, Moroncini G, Negrini SM, Neumann T, Nolasco S, Novikov P, Padoan R, Rivera CM, Roccatello D, Salvarani C, Samson M, Schroeder JW, Seeliger B, Sinico RA, Solans R, Tcherakian C, Toniati P, Treppo E, Trivioli G, Urban ML, Vacca A, Vaglio A   +62 more
core   +1 more source

An Algorithm for the Diagnosis and Management of Severe Asthma in Children and Adolescents

Allergy, Volume 81, Issue 1, Page 307-310, January 2026.
Eckard Hamelmann, Bianca Schaub, Susanne Lau, Leonard B. Bacharier   +3 more
wiley   +1 more source

Effect of benralizumab treatment on the airway microbiome in COPD

ERJ Open Research
Background One-third of patients with COPD have an eosinophilic inflammatory phenotype. Benralizumab is an afucosylated humanised monoclonal antibody that targets the interleukin-5 receptor α subunit, leading to rapid and near-complete eosinophil ...
Koirobi Haldar, Vijay Mistry, Mathew Richardson, Corinne Hamblet, Maria Jison, Michael R. Barer, Christopher McCrae, Christopher E. Brightling   +7 more
doaj   +1 more source

Benralizumab, an add-on treatment for severe eosinophilic asthma: evaluation of exacerbations, emergency department visits, lung function, and oral corticosteroid use

Therapeutics and Clinical Risk Management, 2018
Diego Jose Maselli,1 Linda Rogers,2 Jay I Peters1 1Division of Pulmonary Diseases and Critical Care, University of Texas Health, San Antonio, TX, USA; 2Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine Mount Sinai &ndash ...
Maselli DJ, Rogers L, Peters JI
doaj  

Two-Year Integrated Efficacy And Safety Analysis Of Benralizumab In Severe Asthma

Journal of Asthma and Allergy, 2019
J Mark FitzGerald,1 Eugene R Bleecker,2 Arnaud Bourdin,3 William W Busse,4 Gary T Ferguson,5 Laura Brooks,6 Peter Barker,6 Ubaldo J Martin6 1Centre for Heart and Lung Health, The Lung Centre Vancouver General Hospital, UBC Institute for Heart and Lung ...
FitzGerald JM, Bleecker ER, Bourdin A, Busse WW, Ferguson GT, Brooks L, Barker P, Martin UJ   +7 more
doaj  

Effectiveness of benralizumab in the Tokyo Asthma Study (TOAST): A real-world prospective interventional trial

Allergology International
Background: Biologics are integral in the management of severe asthma. As the effectiveness of the anti-IL-5 receptor antibody benralizumab in Japan remains elusive, this study aimed to assess its real-world effectiveness in Japanese patients with severe
Katsunori Masaki, Maho Suzukawa, Hitoshi Sasano, Norihiro Harada, Yasunari Miyazaki, Hideki Katsura, Etsuko Tagaya, Junko Terada, Masayuki Hojo, Naoya Sugimoto, Hiroyuki Nagase, Yuta Kono, Hisato Hiranuma, Yasuhiro Gon, Ryo Takemura, Misato Irie, Reina Nakamura, Hiroki Kabata, Jun Miyata, Koichi Fukunaga   +19 more
doaj   +1 more source

Benralizumab in Real Life [PDF]

Journal of Investigational Allergology and Clinical Immunology, 2021
J C, Miralles López, A I, Escudero Pastor, A, Carbonell Martínez, C, Navarro Garrido, Y, Bonilla Pacheco, Y, Petrik Petrik   +5 more
openaire   +2 more sources

Treating eosinophilic exacerbations of asthma and COPD with benralizumab (ABRA):a double-blind, double-dummy, active placebo-controlled randomised trial [PDF]

BACKGROUND: Exacerbations of asthma and chronic obstructive pulmonary disease (COPD) are important events and are associated with critical illness. Eosinophilic inflammation is a treatable trait commonly found during acute exacerbations of asthma and ...
Bafadhel, Mona, Bengtsson, Thomas, Bermejo-Sanchez, Laura, Howell, Imran, Krassowska, Karolina, Mahdi, Mahdi, Mahmood, Hafiz R., Melhorn, James, Mwasuku, Christine, Pavord, Ian D., Peterson, Stefan, Ramakrishnan, Sanjay, Russell, Richard E.K.   +12 more
core   +2 more sources