Results 1 to 10 of about 16,365 (187)

Cytotoxicity and Antimicrobial Activity of GaMF1 Analogs. [PDF]

ChemMedChem
GaMF1 is a reported, highly potent inhibitor of mycobacterial ATP synthase. Structural modification of this scaffold significantly changes biological activity. We present GaMF1 analogues with strong antiparasitic effects, potential antiproliferative properties, and discuss the selectivity limitations of the parent compound and its analogues.
Chasák J, Vyvlečka P, Nemec I, Matheeussen A, Van Pelt N, Cos P, Caljon G, Kryštof V, Brulíková L.   +8 more
europepmc   +2 more sources

Do Amino-Oxetanes Resemble Amides? A Matched Molecular Pairs Property and Structural Comparison. [PDF]

J Med Chem
Ishikura H, Begg CS, Rojas JJ, Blagojevic L, Smith GJ, Luk J, Croft RA, Romain C, Choi C, Bull JA.   +9 more
europepmc   +1 more source

Microstructure of amide-functionalized polyethylenes determined by NMR relaxometry. [PDF]

Chem Sci
Haber S, Ciccia NR, Peng Z, Yang F, Im J, Hua M, Fricke SN, Giovine R, Helms BA, Wang C, Hartwig JF, Reimer JA.   +11 more
europepmc   +1 more source

Intramolecular transamidation enables one-pot synthesis of three chiral, Z-shaped perilenediimides for null-type supramolecular polymer formation. [PDF]

Chem Sci
Schwalb AJ, Carreño A, García F, Sánchez L.   +3 more
europepmc   +1 more source

Sequential Formal (4 + 1)-Spirocycloaddition/Oxidative Cleavage between Indoles and <i>β</i>‑Nitrostyrenes: One-Pot Route to Benzamide-Containing (3),4,5-Substituted Isoxazoles. [PDF]

ACS Omega
Arutiunov NA, Zatsepilina AM, Tolstov KV, Shtal DA, Aksenov NA, Aksenov AV.   +5 more
europepmc   +1 more source

Comprehensive Structure-Activity Relationship Analysis of Benzamide Derivatives as Histone Deacetylase 1 (HDAC1) Inhibitors. [PDF]

Int J Mol Sci
Soto-Delgado J, Rodríguez-Núñez YA, Guerra C, Prent-Peñaloza L, Bacho M.   +4 more
europepmc   +1 more source

HDAC inhibitors as anticancer drugs: chemical diversity, clinical trials, challenges and perspectives. [PDF]

RSC Adv
Abdallah AE.
europepmc   +1 more source

Integrative computational, synthetic, experimental evaluation of targeted inhibitors against matrix metalloproteinase-9: Toward precision modulation of proteolytic activity. [PDF]

PLoS One
Rashid ZA, Sabbah DA, Sweidan K, Hajjo R, Bardaweel SK.   +4 more
europepmc   +1 more source

Design and Synthesis of Thiadiazole Derivatives as Dual EGFR/COX‑2 Inhibitors with Anticancer and Anti-inflammatory Activities. [PDF]

ACS Omega
Hidir A, Osmaniye D, Sağlik Özkan BN, Levent S, Kaplancikli ZA, Özkay Y.   +5 more
europepmc   +1 more source

Design, Synthesis and Multitarget Biological Evaluation of Perfluoroalkylated Benzoylthiourea Compounds: From Biofilm Disruption to DNA Cleavage. [PDF]

ACS Omega
Yılmaz MK, Esen MK, Yalçın MS, İnce S, Özdemir S.   +4 more
europepmc   +1 more source