Results 21 to 30 of about 38,481 (291)
A structural systematic study of four isomers of difluoro-N-(3-pyridyl)benzamide [PDF]
The four isomers 2,4-, (I), 2,5-, (II), 3,4-, (III), and 3,5-difluoro-N-(3-pyridyl)benzamide, (IV), all with formula C12H8F2N2O, display molecular similarity, with interplanar angles between the C6/C5N rings ranging from 2.94 (11)° in (IV) to 4.48 (18 ...
Anderson, Frankie P. +3 more
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N-(3-Methylphenyl)benzamide [PDF]
The asymmetric unit of the title compound, C(14)H(13)NO, contains four mol-ecules, which are linked through N-H⋯O hydrogen bonds into two symmetry-independent chains running parallel to [001] and [101]. The N-H and C=O bonds of the amide groups are trans oriented in all four mol-ecules.
B. Thimme Gowda +3 more
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Crystal structure of N-[(morpholin-4-yl)(thiophen-2-yl)methyl]benzamide
In the title compound, C16H18N2O2S, the morpholine ring adopts a chair conformation. The thiophene ring makes a dihedral angle of 63.54 (14)° with the mean plane of the four C atoms [maximum deviation = 0.010 (3) Å] of the morpholine ring.
S. Arun Prabhu +4 more
doaj +1 more source
Evaluation of melanin-targeted radiotherapy in combination with radiosensitizing drugs for the treatment of melanoma [PDF]
The incidence of malignant melanoma is rising faster than that of any other cancer in the United States. An [131I]-labeled benzamide - [131I]MIP-1145 - selectively targets melanin, reduces melanoma tumor burden and increases survival in preclinical ...
Babich, John +5 more
core +1 more source
2-(Methylsulfinyl)benzamide [PDF]
In the crystal of the title compound, C(8)H(9)NO(2)S, synthesized by the oxidation of 2-(methyl-sulfan-yl)benzamide using NaOCl with 2,2,6,6-tetra-methyl-piperidyl-1-oxy (TEMPO) as the catalyst, mol-ecules are linked via inter-molecular N-H⋯O(amide) hydrogen bonds, forming centrosymmetric amide-amide dimers which are extended into a two-dimensional ...
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N-(2-Nitrophenyl)benzamide [PDF]
In the title compound, C(13)H(10)N(2)O(3), the central C-C(=O)-N-C amide unit makes dihedral angles of 21.68 (4) and 19.08 (4)°, respectively, with the phenyl and nitro-benzene rings. The two aromatic rings are inclined at 3.74 (3)° and the nitro group is skewed out of the attached benzene ring plane by 18.55 (8)°. An intra-molecular N-H⋯O inter-action
Aamer Saeed, Jim Simpson
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4-Methyl-N-[2-(pyridin-2-yl)ethylcarbamothioyl]benzamide
In the title compound, C16H17N3OS, the dihedral angle between the planes of the benzene and pyridine rings is 71.33 (15)°. An intramolecular N—H...O hydrogen bond is present.
Farook Adam +2 more
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N-(3,4-Dimethylphenyl)benzamide [PDF]
The conformation of the NH bond in the structure of the title compound (N34DMPBA), C(15)H(15)NO, is anti to the meta-methyl substituent in the aniline ring, similar to that observed with respect to the meta-chloro substituent in N-(3,4-dichloro-phen-yl)benzamide (N34DCPBA), but in contrast to the syn conformation observed with respect to the meta ...
B. Thimme Gowda +4 more
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Crystal structure of 4-methyl-N-{[1-(4-methylbenzoyl)piperidin-4-yl]methyl}benzamide
In the title compound, C22H27N2O2, the piperidine ring adopts a half-chair conformation with the benzene rings inclined in a trans orientation with respect to the piperidine ring [dihedral angle between the benzene rings = 89.1 (1)°].
K. Prathebha +4 more
doaj +1 more source
Positive allosteric modulators of the a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor [PDF]
L-glutamate is the major excitatory neurotransmitter in the mammalian central nervous system (CNS) and plays a fundamental role in the control of motor function, cognition and mood.
Grove, Simon J .A. +4 more
core +1 more source

