Pharmacological Potential of 3-Benzazepines in NMDAR-Linked Pathophysiological Processes [PDF]
Biomedicines, 2023 The number of N-Methyl-D-aspartate receptor (NMDAR) linked neurodegenerative diseases such as Alzheimer’s disease and dementia is constantly increasing. This is partly due to demographic change and presents new challenges to societies. To date, there are
Nadine Ritter +4 more
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Stereocontrolled addition of Grignard reagents to oxa-bridged benzazepines: highly efficient synthesis of functionalized benzazepine scaffolds. [PDF]
RSC Adv, 2020 An efficient and highly diastereoselective synthesis of 2-substituted benzo[b]azepin-5-olviastereocontrolled addition of Grignard reagents to oxa-bridged benzazepines has been developed.
Zhang Y, Bao Q, Zhang N, Wang S, Yu X.
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Divergent synthesis of benzazepines and bridged polycycloalkanones via dearomative rearrangement [PDF]
Nature Communications, 2022 The dearomative functionalization of aromatic compounds represents a challenging transformation, as it typically needs to overcome a great kinetic barrier.
Qiu Shi +10 more
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Palladium-Catalyzed [5 + 2] Rollover Annulation of 1-Benzylpyrazoles with Alkynes: A Direct Entry to Tricyclic 2-Benzazepines. [PDF]
Org Lett, 2023 The first Pd-catalyzed [5 + 2] rollover annulation of 1-benzylpyrazoles with alkynes to assemble 10H-benzo[e]pyrazolo[1,5-a]azepines (tricyclic 2-benzazepines) has been developed.
Suárez-Lustres A +4 more
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Chiral Ligands Based on Binaphthyl Scaffolds for Pd-Catalyzed Enantioselective C-H Activation/Cycloaddition Reactions. [PDF]
J Am Chem Soc, 2022 info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/REDES METAL-ORGANICAS PARA LA VALORIZACION DE BIOMASA A TRAVES DE SIMULACIONES DE SISTEMAS CATALITICOSWe report the first examples of the use of ...
González JM +4 more
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Heck–Suzuki Tandem Reaction for the Synthesis of 3-Benzazepines [PDF]
The Journal of Organic Chemistry, 2015 AbstractThe microwave‐assisted title reaction between N‐protected 2‐(2‐bromoaryl)alkylpropargylamides and organo‐boron compounds gives the corresponding 3‐benzazepin‐2‐ones.
Anatoly A. Peshkov +5 more
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Convenient Synthesis of 2‐Benzazepines via Radical Cyclization. [PDF]
The Journal of Organic Chemistry, 2003 AbstractFor Abstract see ChemInform Abstract in Full Text.
Akio Kamimura +3 more
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Some derivatives of 1-benzazepine [PDF]
Canadian Journal of Chemistry, 1969 A new rearrangement of a substituted 5H-1-benzazepine-5-one is described. A new route to certain dimethyl-1-benzazepines has been developed and linked up with a known synthesis. Several new derivatives of 1-benzazepine are reported.
A. H. REES, K. Simon
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Nitrogen atom insertion into arenols to access benzazepines. [PDF]
Chem SciHe Y, Wang J, Zhu T, Zheng Z, Wei H.
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