Results 11 to 20 of about 6,469 (247)

Stereocontrolled addition of Grignard reagents to oxa-bridged benzazepines: highly efficient synthesis of functionalized benzazepine scaffolds. [PDF]

open access: goldRSC Adv, 2020
An efficient and highly diastereoselective synthesis of 2-substituted benzo[b]azepin-5-olviastereocontrolled addition of Grignard reagents to oxa-bridged benzazepines has been developed.
Zhang Y, Bao Q, Zhang N, Wang S, Yu X.
europepmc   +6 more sources

Heck–Suzuki Tandem Reaction for the Synthesis of 3-Benzazepines [PDF]

open access: greenThe Journal of Organic Chemistry, 2015
AbstractThe microwave‐assisted title reaction between N‐protected 2‐(2‐bromoaryl)alkylpropargylamides and organo‐boron compounds gives the corresponding 3‐benzazepin‐2‐ones.
Anatoly A. Peshkov   +5 more
semanticscholar   +6 more sources

Catalytic Cyclization of o‐Alkynyl Phenethylamines via Osmacyclopropene Intermediates: Direct Access to Dopaminergic 3‐Benzazepines [PDF]

open access: yesAngewandte Chemie, 2015
NOTICE: This is the peer reviewed version of the following article: Álvarez-Pérez, A., González-Rodríguez, C., García-Yebra, C., Varela, J. A., Oñate, E., Esteruelas, M. A., Saá, C. (2015).
Esteruelas Rodrigo, Miguel Ángel   +6 more
core   +2 more sources

Preparation of substituted tetrahydro-1-benzazepines by lithiation-trapping [PDF]

open access: yesAnnalen der Pharmacie, 2018
The tetrahydro‐1‐benzazepine or benzo[b]azepine ring system is found in a number of drug molecules although methods to access 2,2‐disubstituted derivatives are rare. Here we report the preparation of N‐tert‐butoxycarbonyl‐2‐phenyltetrahydro‐1‐benzazepine
Aeyad   +38 more
core   +2 more sources

Synthesis and evaluation of variably substituted N-methyl tetrahydroisoquinolines and benzazepines as monoamine reuptake inhibitors

open access: yesResults in Chemistry, 2022
The use of N-methyl-1, 2, 3, 4-tetrahydroisoquinoline as pharmacophores has been studied over the years. It has a structural similarity with the N, N-dimethyl phenethylamine, a framework entrenched in the drug venlafaxine, acknowledged for its ...
Sneh Lata   +5 more
doaj   +1 more source

Review on allosteric modulators of dopamine receptors so far. [PDF]

open access: yesHealth Sci Rep
Abstract Background Contemporary research is predominantly directed towards allosteric modulators, a class of compounds designed to interact with specific sites distinct from the orthosteric site on G protein‐coupled receptors. These allosteric modulators play a pivotal role in influencing diverse pharmacological effects, such as agonism/inverse ...
Girmaw F.
europepmc   +2 more sources

Convenient Synthesis of 2‐Benzazepines via Radical Cyclization. [PDF]

open access: greenThe Journal of Organic Chemistry, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Akio Kamimura   +3 more
openalex   +5 more sources

Recent Advances in the Development of Catalytic Methods that Construct Medium-Ring Lactams, Partially Saturated Benzazepines and Their Derivatives

open access: yesSynthesis, 2021
Recent catalytic methods to construct medium-sized lactams and partially saturated benzazepines and their derivatives are surveyed. The review is divided into the following sections: 1 Introduction 2 Non-Transition-Metal-Catalyzed Reactions 2.1 Beckmann ...
T. Driver, Wrickban Mazumdar
semanticscholar   +1 more source

Some derivatives of 1-benzazepine [PDF]

open access: bronzeCanadian Journal of Chemistry, 1969
A new rearrangement of a substituted 5H-1-benzazepine-5-one is described. A new route to certain dimethyl-1-benzazepines has been developed and linked up with a known synthesis. Several new derivatives of 1-benzazepine are reported.
A. H. REES, K. Simon
openalex   +3 more sources

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