Results 11 to 20 of about 6,469 (247)
Stereocontrolled addition of Grignard reagents to oxa-bridged benzazepines: highly efficient synthesis of functionalized benzazepine scaffolds. [PDF]
An efficient and highly diastereoselective synthesis of 2-substituted benzo[b]azepin-5-olviastereocontrolled addition of Grignard reagents to oxa-bridged benzazepines has been developed.
Zhang Y, Bao Q, Zhang N, Wang S, Yu X.
europepmc +6 more sources
Heck–Suzuki Tandem Reaction for the Synthesis of 3-Benzazepines [PDF]
AbstractThe microwave‐assisted title reaction between N‐protected 2‐(2‐bromoaryl)alkylpropargylamides and organo‐boron compounds gives the corresponding 3‐benzazepin‐2‐ones.
Anatoly A. Peshkov+5 more
semanticscholar +6 more sources
Catalytic Cyclization of o‐Alkynyl Phenethylamines via Osmacyclopropene Intermediates: Direct Access to Dopaminergic 3‐Benzazepines [PDF]
NOTICE: This is the peer reviewed version of the following article: Álvarez-Pérez, A., González-Rodríguez, C., García-Yebra, C., Varela, J. A., Oñate, E., Esteruelas, M. A., Saá, C. (2015).
Esteruelas Rodrigo, Miguel Ángel+6 more
core +2 more sources
Preparation of substituted tetrahydro-1-benzazepines by lithiation-trapping [PDF]
The tetrahydro‐1‐benzazepine or benzo[b]azepine ring system is found in a number of drug molecules although methods to access 2,2‐disubstituted derivatives are rare. Here we report the preparation of N‐tert‐butoxycarbonyl‐2‐phenyltetrahydro‐1‐benzazepine
Aeyad+38 more
core +2 more sources
The use of N-methyl-1, 2, 3, 4-tetrahydroisoquinoline as pharmacophores has been studied over the years. It has a structural similarity with the N, N-dimethyl phenethylamine, a framework entrenched in the drug venlafaxine, acknowledged for its ...
Sneh Lata+5 more
doaj +1 more source
Review on allosteric modulators of dopamine receptors so far. [PDF]
Abstract Background Contemporary research is predominantly directed towards allosteric modulators, a class of compounds designed to interact with specific sites distinct from the orthosteric site on G protein‐coupled receptors. These allosteric modulators play a pivotal role in influencing diverse pharmacological effects, such as agonism/inverse ...
Girmaw F.
europepmc +2 more sources
Convenient Synthesis of 2‐Benzazepines via Radical Cyclization. [PDF]
AbstractFor Abstract see ChemInform Abstract in Full Text.
Akio Kamimura+3 more
openalex +5 more sources
Recent catalytic methods to construct medium-sized lactams and partially saturated benzazepines and their derivatives are surveyed. The review is divided into the following sections: 1 Introduction 2 Non-Transition-Metal-Catalyzed Reactions 2.1 Beckmann ...
T. Driver, Wrickban Mazumdar
semanticscholar +1 more source
Some derivatives of 1-benzazepine [PDF]
A new rearrangement of a substituted 5H-1-benzazepine-5-one is described. A new route to certain dimethyl-1-benzazepines has been developed and linked up with a known synthesis. Several new derivatives of 1-benzazepine are reported.
A. H. REES, K. Simon
openalex +3 more sources