Results 21 to 30 of about 4,384 (210)
Asymmetric Catalytic Transformations of Aza‐ortho‐ and Aza‐para‐Quinone Methides
ChemCatChem, Volume 15, Issue 13, July 7, 2023., 2023 Aza‐quinone methides (aza‐QMs) are transient intermediates, which are able to react easily with a variety of nucleophiles providing a variety of N‐heterocycles. The catalytic methodologies for the derivatization of aza‐QM into chiral derivatives have been recently reported and involve organocatalytic or organometallic approaches.
Mercedes Zurro, Aitor Maestro
wiley +1 more source
Electrochemical oxidative radical cascade cyclization of dienes and diselenides towards the synthesis of seleno-benzazepines. [PDF]
RSC AdvHu L, Zhang J, Li M, Feng Y, Lu F.
europepmc +3 more sources
Iodine(III)‐Mediated Oxidation of Anilines to Construct Dibenzazepines**
Chemistry – A European Journal, Volume 29, Issue 37, July 3, 2023., 2023 Cyclization: A mild, room temperature oxidative cyclization of 2‐substituted anilines that accesses a broad range of medium‐ring N‐heterocycles via radical intermediates is reported. Abstract The development of an efficient process that produces bioactive medium‐sized N‐heterocyclic scaffolds from 2‐substituted anilines using either iodosobenzene or ...
Carmen Margaret White +3 more
wiley +1 more source
Carbotrifluoromethylations of C−C Multiple Bonds (Excluding Aryl‐ and Alkynyltrifluoromethylations)
Chemistry – A European Journal, Volume 29, Issue 19, April 3, 2023., 2023 One main method for the access of organofluorine compounds is the trifluoromethylative functionalization of an olefin bond, which simultaneously introduces a functional group and a trifluoromethyl element into an olefin framework. This review provides a concise overview of this powerful and versatile method. Abstract Organofluorine chemistry has become
Klára Aradi, Loránd Kiss
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Unravelling benzazepines and aminopyrimidine as multi-target therapeutic repurposing drugs for EGFR V774M mutation in neuroglioma patients [PDF]
BioImpactsIntroduction: Neuroglioma, a classification encompassing tumors arising from glial cells, exhibits variable aggressiveness and depends on tumor grade and stage.
Jitender Singh +2 more
doaj +1 more source
Review on allosteric modulators of dopamine receptors so far. [PDF]
Health Sci RepAbstract Background Contemporary research is predominantly directed towards allosteric modulators, a class of compounds designed to interact with specific sites distinct from the orthosteric site on G protein‐coupled receptors. These allosteric modulators play a pivotal role in influencing diverse pharmacological effects, such as agonism/inverse ...
Girmaw F.
europepmc +2 more sources
Acta Crystallographica Section E: Crystallographic Communications, 2016 The title compounds, C22H29NO2 (3) and C22H29NO2 (4) [systematic names: (1S*,2R*)-7-methoxy-2-methyl-3-(4-phenylbutyl)-2,3,4,5-tetrahydro-1H-3-benzazepin-1-ol and (1R*,2R*)-7-methoxy-2-methyl-3-(4-phenylbutyl)-2,3,4,5-tetrahydro-1H-3-benzazepin-1-ol, are
Bastian Tewes +3 more
doaj +1 more source
Graph-Sparse LDA: A Topic Model with Structured Sparsity [PDF]
, 2014 Originally designed to model text, topic modeling has become a powerful tool for uncovering latent structure in domains including medicine, finance, and vision.
Adams, Ryan +2 more
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Acta Crystallographica Section E: Crystallographic Communications, 2016 In the title compound, C25H27NO4S, which crystallized as a racemate, the relative configuration of the adjacent OH and CH3 groups on the azepine ring is trans. The seven-membered azepin ring has a chair-like conformation. The planar aromatic rings of the
Bastian Tewes +3 more
doaj +1 more source
Impact of spermiogram and sperm function test in idiopathic recurrent pregnancy loss [PDF]
, 2015 Aims: To evaluate the role of sperm factors in idiopathic recurrent pregnancy loss cases. Methods: We recruited 100 male subjects where their female partners experienced 2 or more idiopathic pregnancy losses.
Chaithra, T. P +3 more
core +1 more source