Results 1 to 10 of about 8,103 (214)

Intracellular Binding of Novel Fluorinated Compounds to Carbonic Anhydrase Isoforms Explored by In-Cell ¹⁹F NMR. [PDF]

J Med Chem
Costantino A, Barbieri L, Giovannuzzi S, Nocentini A, Supuran CT, Raitelaitis M, Nordlund P, Banci L, Luchinat E.   +8 more
europepmc   +1 more source

An ureido-substituted benzenesulfonamide carbonic anhydrase inhibitor exerts a potent antitumor effect in vitro and in vivo. [PDF]

Exp Hematol Oncol
Gazzaroli G, Tavani C, Filiberti S, Massardi ML, Turati M, Garattini G, Peat TS, Pieraccini G, Angeli A, Supuran CT, Carta F, Giacomini A, Ronca R.   +12 more
europepmc   +1 more source

Design, synthesis, biological evaluation and in silico studies of 2-anilino- 4-(benzimidazol- 1-yl)pyrimidine scaffold as antitumor agents. [PDF]

Saudi Pharm J
Al-Rasheed LS, Ansari SA, Asiri HH, Bakheit AH, Al-Mehizia AA, Alsegiani AS, Alkahtani HM.   +6 more
europepmc   +1 more source

Development of Novel Sulfonamide-Based Pyrazole-Clubbed Pyrazoline Derivatives: Synthesis, Biological Evaluation, and Molecular Docking Study. [PDF]

ACS Omega
Zala M, Vora JJ, Khedkar VM, Almalki AH, Tivari S, Jatvada R.   +5 more
europepmc   +1 more source

Novel Derivatives of 3-Amino-4-hydroxy-benzenesulfonamide: Synthesis, Binding to Carbonic Anhydrases, and Activity in Cancer Cell 2D and 3D Cultures. [PDF]

Int J Mol Sci
Vainauskas V, Norvaišaitė R, Grybaitė B, Vaickelionienė R, Smirnov A, Kojis T, Baranauskiene L, Manakova E, Gražulis S, Zubrienė A, Matulis D, Mickevičius V, Petrikaitė V.   +12 more
europepmc   +1 more source

Theoretical Basis for Refractive Index Changes Resulting from Solution Phase Molecular Interaction. [PDF]

J Phys Chem B
Kammer MN, Kussrow AK, Bornhop DJ.
europepmc   +1 more source

Pharmacophoric 2-hydroxyalkyl benzenesulfonamide: A single-step synthesis from benzenesulfonamide via hemiaminal

European Journal of Medicinal Chemistry, 2007
ortho-Acylation attempt of benzenesulfonamide afforded the corresponding hemiaminal as major product. The in situ reduction of the reaction mixture, reported herein, directly provided 2-hydroxyalkyl benzenesulfonamide, an important pharmacophoric element for designing drug-like scaffolds. Its application is demonstrated through designing a novel series
P Praveen Kumar, J Moses Babu, K Vyas
exaly   +4 more sources