Results 31 to 40 of about 8,103 (214)

Novel sulphonamide-bearing methoxyquinazolinone derivatives as anticancer and apoptosis inducers: synthesis, biological evaluation and in silico studies

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
We synthesised a new series of sulphonamide-bearing quinazolinone derivatives 5-18 and evaluated their in vitro cytotoxicity in various cancer cell lines (A549, HepG-2, LoVo and MCF-7) and in normal human cells (HUVEC).
Ali S. Alqahtani, Mostafa M. Ghorab, Fahd A. Nasr, Mohammad Z. Ahmed, Abdullah A. Al-Mishari, Sabry M. Attia   +5 more
doaj   +1 more source

Spectroscopic and photophysicochemical properties of zinc(II) phthalocyanine substituted with benzenesulfonamide units containing schiff base [PDF]

, 2022
In this study, compounds (E)-4-((5-bromo-2-hydroxy-3-methoxybenzylidene)amino)-N-(pyridin-2-yl)benzenesul-fonamide 1, (E)-4-((5-bromo-2-(3,4-dicyanophenoxy)-3-methoxybenzylidene)amino)-N-(pyridin-2-yl)benzenesulfonamide 2 and, complex 2(3),9(10),16(17 ...
Ozturk, Omer Faruk, Oncul, Gulen Atiye, Piskin, Mehmet   +2 more
core   +3 more sources

Synthesis and Antimicrobial Evaluation of Some New Pyrazolo[1,5-a]pyrimidine and Pyrazolo[1,5-c]triazine Derivatives Containing Sulfathiazole Moiety

Acta Chimica Slovenica, 2020
A number of important fused heterocyclic systems have been prepared by the reaction of 4-((3,5-diamino-1H-pyrazol-4-yl)-diazenyl)-N-(thiazol-2-yl)-benzenesulfonamide with some bifunctional nucleophiles such as ethyl acetoacetate, acetylacetone or ...
Elsherbiny Hamdy El-Sayed, Ahmed Ali Fadda, Ahmed Mohamed El-Saadaney   +2 more
doaj   +1 more source

New Antioxidant Agents Bearing Carboxamide Moiety: Synthesis, Molecular Docking and in Vitro Studies of New Benzenesulfonamide Derivatives [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2021
Oxidative stress occurs when oxygen radical formation and levels exceed those of antioxidants, potentiating cell responses such as apoptosis, tumorigenesis, and immune response.
Florence Eze, Uchechukwu Okoro, Pius Ukoha, David Ugwu, Sunday Okafor   +4 more
doaj   +1 more source

Finding the Right Solvent: A Novel Screening Protocol for Identifying Environmentally Friendly and Cost-Effective Options for Benzenesulfonamide

Molecules, 2023
This study investigated the solubility of benzenesulfonamide (BSA) as a model compound using experimental and computational methods. New experimental solubility data were collected in the solvents DMSO, DMF, 4FM, and their binary mixtures with water. The
Piotr Cysewski, Tomasz Jeliński, Maciej Przybyłek   +2 more
doaj   +1 more source

Synthesis, Molecular Docking Analysis, and Carbonic Anhydrase Inhibitory Evaluations of Benzenesulfonamide Derivatives Containing Thiazolidinone

Molecules, 2019
To find novel human carbonic anhydrase (hCA) inhibitors, we synthesized thirteen compounds by combining thiazolidinone with benzenesulfonamide. The result of the X-ray single-crystal diffraction experiment confirmed the configuration of this class of ...
Zuo-Peng Zhang, Ze-Fa Yin, Jia-Yue Li, Zhi-Peng Wang, Qian-Jie Wu, Jian Wang, Yang Liu, Mao-Sheng Cheng   +7 more
doaj   +1 more source

Design, synthesis, and evaluation of 1,2,3-triazole-based benzenesulfonamide and flavonol hybrid molecules as anticancer agents

, 2023
Background The design and synthesis of hybrid molecules will explore finding new drugs. Objectives The synthesized hybrid molecules to evaluate their biological properties.
Shih, Tzenge-lien
core   +1 more source

Crystal and molecular structures of 3-amino-4-hydroxy benzenesulfonamide and its hydrochloride: Quantum-chemical study of their tautomerism

, 2020
3-amino-4-hydroxy benzenesulfonamide and its hydrochloride have been isolated in the crystalline state. Their crystal and molecular structures are determined by X-ray diffraction.
Strashnova S.B., Zaitsev B.E., Strashnov P.V., Kovalchukova O.V., Romashkina E.P., Sergienko V.S.   +5 more
core   +2 more sources

Crystal structure of N-(1-allyl-3-chloro-4-ethoxy-1H-indazol-5-yl)-4-methoxybenzenesulfonamide

Acta Crystallographica Section E, 2014
In the title compound, C19H20ClN3O4S, the benzene ring is inclined to the indazole ring system (r.m.s. deviation = 0.014 Å) by 65.07 (8)°. The allyl and ethoxy groups are almost normal to the indazole ring, as indicated by the respective torsion angles ...
Hakima Chicha, El Mostapha Rakib, Latifa Bouissane, Mohamed Saadi, Lahcen El Ammari   +4 more
doaj   +1 more source

N-(2-Methylphenyl)benzenesulfonamide [PDF]

, 2008
In the title compound, C13H13NO2S, the conformation of the N—H bond is anti to the ortho-methyl group on the aniline ring, in contrast to the syn conformation observed with respect to the ortho-chloro group in N-(2-chlorophenyl)benzenesulfonamide ...
K. S. Babitha, Hartmut Fuess, Sabine Foro, B. Thimme Gowda   +3 more
core   +1 more source