Results 41 to 50 of about 8,103 (214)

4-(1H-Pyrazol-1-yl) Benzenesulfonamide Derivatives: Identifying New Active Antileishmanial Structures for Use against a Neglected Disease

Molecules, 2012
Leishmaniasis is a neglected disease responsible for about 56,000 deaths every year. Despite its importance, there are no effective, safe and proper treatments for leishmaniasis due to strain resistance and/or drug side-effects.
Leonor L. Leon, Veronica F. Amaral, Marilene M. Canto-Cavalheiro, Carlos R. Rodrigues, Júlio C. Borges, Alessandra M. T. Souza, Cesar D. Oliveira, Helena C. Castro, Marie-Luce F. Lira, Tathiane A. Proux, Karen S. Charret, Alice M. R. Bernardino, Roberta K. F. Marra   +12 more
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2-(Hydrazinocarbonyl)benzenesulfonamide

Acta Crystallographica Section E Structure Reports Online, 2007
In the title compound, C7H9N3O3S, the chiral conformation of the mol­ecule is determined by an intra­molecular N—H⋯O hydrogen bond between the sulfonamide and hydrazino­carbonyl groups, with the former group acting as a donor in hydrogen bonding. The crystal structure is stabilized by inter­molecular N—H⋯O and N—H⋯N hydrogen bonds and π–π stacking ...
Shu-Yan Wang, Wan-Cheng Guo, Ning Ma
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Synthesis and antidiabetic evaluation of benzenesulfonamide derivatives.

Iranian journal of pharmaceutical research : IJPR, 2013
The complex metabolic syndrome, diabetes mellitus, is a major human health concern in the world and is estimated to affect 300 million people by the year 2025. Several drugs such as sulfonylureas and biguanides are presently available to reduce hyperglycemia in diabetes mellitus.
Hosseinzadeh, Nouraddin, Seraj, Soodeh, Bakhshi-Dezffoli, Mohamad Ebrahim, Hasani, Mohammad, Khoshneviszadeh, Mehdi, Fallah-Bonekohal, Saeed, Abdollahi, Mohammad, Foroumadi, Alireza, Shafiee, Abbas   +8 more
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Novel sulfonamide benzoquinazolinones as dual EGFR/HER2 inhibitors, apoptosis inducers and radiosensitizers

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
A series of sulfonamide benzoquinazolinones 5–18 was synthesized and evaluated for cytotoxic activity against MDA-MB-231 cell line. The compounds showed IC50 ranging from 0.26 to 161.49 µM.
Aiten M. Soliman, Ali S. Alqahtani, Mostafa M. Ghorab   +2 more
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Schiff bases derived from 4-amino-N-substituted benzenesulfonamide: synthesis, spectral characterisation and MIC evaluation

, 2021
. The present study is aimed to synthesise Schiff bases from sulfathiazole/ sulfamethoxazole/ sulfadimidine with 2-hydroxybenzaldehyde. The synthesized Schiff bases were characterized by analytical data, IR, 1H-NMR, 13C-NMR, UV-Vis spectra, mass spectra ...
Nisha, C., Valarmathy, G., Sabarika, B., Subbalakshmi, R.   +3 more
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A Comparative Test on the Sensitivity of Freshwater and Marine Microalgae to Benzo-Sulfonamides, -Thiazoles and -Triazoles

Applied Sciences, 2021
The evaluation of the ecotoxicological effects of water pollutants is performed by using different aquatic organisms. The effects of seven compounds belonging to a class of widespread contaminants, the benzo-fused nitrogen heterocycles, on a group of ...
Luca Canova, Michela Sturini, Federica Maraschi, Stefano Sangiorgi, Elida Nora Ferri   +4 more
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Synthesis and Antimicrobial Evaluation of Novel Hydrazones and 1,3,4-Oxadiazoles Incorporating Bumetanide Derivatives [PDF]

Records of Pharmaceutical & Biomedical Sciences, 2018
The aim of this study is to synthesize new benzenesulfonamide derivatives that possess antibacterial activity using Bumetanide as a precursor of benzenesulfonamide.
Mahmoud Bendary, Ahmed Abdulrahmanf, Ibrahim Salem, Tarek Ibrahim, Osama El-Sabbag, Samia Mostafa   +5 more
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Design, Synthesis and Biological Assessment of Rhodanine-Linked Benzenesulfonamide Derivatives as Selective and Potent Human Carbonic Anhydrase Inhibitors

Molecules, 2022
A novel series of twenty-five rhodamine-linked benzenesulfonamide derivatives (7a–u and 9a–d) were synthesized and screened for their inhibitory action against four physiologically relevant human (h) carbonic anhydrase (CA) isoforms, namely hCA I, hCA II,
Baijayantimala Swain, Abrar Khan, Priti Singh, Vaibhav S. Marde, Andrea Angeli, Krishna Kartheek Chinchilli, Venkata Madhavi Yaddanapudi, Simone Carradori, Claudiu T. Supuran, Mohammed Arifuddin   +9 more
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Synthesis, Antibacterial and Antifungal Activity of Some New Pyrazoline and Pyrazole Derivatives

Molecules, 2013
A series of 2-pyrazolines 5–9 have been synthesized from α,β-unsaturated ketones 2–4. New 2-pyrazoline derivatives 13–15 bearing benzenesulfonamide moieties were then synthesized by condensing the appropriate chalcones 2–4 with 4-hydrazinyl ...
Seham Y. Hassan
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Discovery of a Novel Benzenesulfonamide Analogue That Inhibits Proliferation and Metastasis Against Ovarian Cancer OVCAR-8 Cells

Drug Design, Development and Therapy, 2020
Yanyan Jia, Meijuan Li, Yuan Cao, Wenlong Feng, Xueru Li, Wenhua Xue, Huirong Shi Department of Gynecology and Obstetrics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, People’s Republic of ChinaCorrespondence: Yanyan ...
Jia Y, Li M, Cao Y, Feng W, Li X, Xue W, Shi H   +6 more
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