Results 21 to 30 of about 4,762 (102)

A Mechanochemical Route for the Synthesis of Diphenyleneiodonium Salts and the Estimation of Their Relative Solid‐State Reactivities

Chemistry–Methods, Volume 5, Issue 9, September 2025.
An efficient mechanochemical route for diphenyleneiodonium (DPI) salt synthesis is reported which offers a sustainable and solvent‐free alternative. The solid‐state reactivities of the reported DPI salts were also assessed with the help of morphology predictions and Hirshfeld surface analysis computations to understand the effect of crystal morphology,
Ipsha Shruti, Tejender S. Thakur
wiley   +1 more source

Modulating Antimicrobial Activity and Structure of the Peptide Esc(1‐21) via Site‐Specific Isopeptide Bond Formation

Journal of Peptide Science, Volume 31, Issue 9, September 2025.
The introduction of an isopeptide bond at the lysine residues in the backbone of Esc(1‐21) led to the generation of five analogs. Among these, Esc(1‐21)ε20 showed the most promising features, having antimicrobial activity comparable with those of the parent peptide, a lower cytotoxicity, and a higher stability to proteolytic degradation.
Bruno Casciaro, Daniel Ben Hur, Daniela Roversi, Carlo Vetrano, Edo Kiper, Giacomo Cappella, Federico Carneri, Eeva Tortellini, Lorenzo Stella, Neta Regev‐Rudzki, Yechiel Shai, Maria Luisa Mangoni   +11 more
wiley   +1 more source

Metal‐Free HFIP‐Promoted Synthesis of Benzhydryl Derivatives from Stilbenes as Masked Electrophiles under Oxidative Conditions

European Journal of Organic Chemistry, Volume 28, Issue 32, August 28, 2025.
An umpolung strategy allowing the use of stilbenes as electrophiles in substitution reactions is developed that relies on a combination of m‐chloroperbenzoic acid and hexafluoroisopropanol. This new step‐economic approach gives rise to benzhydryl derivatives by the use of different nitrogenated, oxygenated, and sulfur‐ and carbon‐based nucleophiles ...
Francisco J. Sierra‐Molero, Alejandro Baeza, Diego A. Alonso, Hernan Rico‐Trilles   +3 more
wiley   +1 more source

Synthesis of Benzodithieno[5.5.5.6]Fenestranes: Unexpected Epimerization and Regiochemical Outcomes

Asian Journal of Organic Chemistry, Volume 14, Issue 7, July 2025.
Isomeric [5.5.5.6]fenestranes annulated with one benzene and two thiophene rings are accessible via di‐2‐ and di‐3‐thienylspirane intermediates. The key double cyclization step involves surprising stereoselectivity and regioselectivity. In particular, cis‐di(2‐thienyl)spirane precursors lead to the all‐cis‐fenestrane skeleton by an unexpected acid ...
Björn Bredenkötter, Wai‐Shing Wong, Man‐Kit Lee, Chun‐Fai Ng, Hak‐Fun Chow, Dietmar Kuck   +5 more
wiley   +1 more source

Advances in Metal‐Free Transamidation: A Sustainable Approach to Amide Bond Formation

Chemistry – An Asian Journal, Volume 20, Issue 12, June 16, 2025.
This review highlights the recent developments of transamidation reactions under metal‐free reaction conditions. Various amines including weak nucleophilic amines such as aromatic amines have been used to achieve the transamidation reactions under mild and relatively green reaction conditions. Abstract The amide functionalities are a crucial functional
Niharan Sivaraj, Toshifumi Dohi, Fateh V. Singh   +2 more
wiley   +1 more source

Abstracts

Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Acid-promoted dehydroxylation coupling of aryl alcohols with 1,3-dicarbonyls and sulfonamides. [PDF]

BMC Chem
Liang J, Liu C, Liang Y, Liao J, Luo R, Ouyang L.   +5 more
europepmc   +1 more source

Total Synthesis and Anticancer Study of (+)-Verticillin A. [PDF]

J Am Chem Soc
Knauss W, Wang X, Filbin MG, Qi J, Movassaghi M.   +4 more
europepmc   +1 more source

Programmable Strategies for the Conversion of Aldehydes to Unsymmetrical (Deuterated) Diarylmethanes and Diarylketones. [PDF]

Org Lett
Gavit VR, Hanania N, Eghbarieh N, Shioukhi I, Masarwa A.   +4 more
europepmc   +1 more source

Enantioconvergent Synthesis of Diarylmethane Drugs via Privileged Benzhydrol Intermediates. [PDF]

J Org Chem
Frank E, Flügel JL, d'Heureuse L, Woick S, Breder A.   +4 more
europepmc   +1 more source