Results 241 to 250 of about 36,788 (280)

The chromatography of benzimidazoles

Journal of Chromatography A, 1973
Summary The thin-layer chromatography of a series of mono- and bis-benzimidazoles has been studied in order to determine the influence of substituents. Results for the gas-liquid chromatography of 2-alkyl-substituted benzimidazoles and their silyl derivatives show that a quasi-exponential relationship exists between retention time and the carbon ...
E R, Cole, G, Crank, A S, Sheikh
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A Field Evaluation of Pro-Benzimidazole, Benzimidazole, and Non-Benzimidazole Anthelmintics in Horses

Journal of the American Veterinary Medical Association, 1981
SUMMARY The effectiveness of 1 pro-benzimidazole (pro-bzd) drug, 3 benzimidazole (bzd) drugs, and 3 non-benzimidazole (non-bzd) drugs in keeping fecal egg counts below 50 eggs per gram 2 and 4 weeks after treatment at 6-week intervals was compared in groups of brood mares and yearlings at 2 Standardbred farms.
R P, Herd, T B, Miller, A A, Gabel
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METABOLISM OF BENZIMIDAZOLE IN WHEAT: I. FORMATION OF BENZIMIDAZOLE NUCLEOTIDE

Canadian Journal of Biochemistry, 1965
An enzyme, probably benzimidazole nucleotide:pyrophosphate phosphoribosyl transferase, has been demonstrated in the 33–65% (NH4)2SO4fraction of wheat embryos. The enzyme was assayed indirectly by the apparent inhibition of the analogous orotidine-5′-phosphate pyrophosphorylase caused by benzimidazole competing with orotate for P-ribosyl-PP.
M, KAPOOR, E R, WAYGOOD
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The metabolism of benzimidazole anthelmintics

Parasitology Today, 1990
The benzimidazole carbamates are important broad-spectrum drugs for the control of helminth parasites in mammals. David Gottschall, Vassilios Theodorides and Richard Wang explain that the metabolism of these compounds depends heavily on the substituent present on carbon-5 of the benzimidazole nucleus and involves a wide variety of reactions.
D W, Gottschall, V J, Theodorides, R, Wang   +2 more
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Biochemistry of benzimidazole resistance

Acta Tropica, 1994
Heavy reliance on the benzimidazole (BZ) anthelmintics since their introduction in the 1960's for the control of gastrointestinal parasites of livestock has led to widespread BZ resistance in target parasite species. The BZs exert their primary action by binding to tubulin, the major protein component of microtubules.
E, Lacey, J H, Gill
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Interaction of anthelmintic benzimidazoles and benzimidazole derivatives with bovine brain tubulin

Biochimica et Biophysica Acta (BBA) - General Subjects, 1978
The binding and inhibitory properties of 11 benzimidazoles for bovine brain tubulin were investigated. The effects of the benzimidazoles on the initial rates of microtubule polymerization were determined by a turbidimetric assay. The median inhibitory concentrations (I50) for nocodazole, oxibendazole, parbendazole, mebendazole and fenbendazole ranged ...
P A, Friedman, E G, Platzer
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Prototropism in 2-acetyl benzimidazole and 2-benzoyl benzimidazole

Journal of Photochemistry and Photobiology A: Chemistry, 2005
2-Acetyl benzimidazole (2ABI) and 2-benzoyl benzimidazole (2BBI) are found to show excited state prototropic activities in different solvents of varying pH. The absorption, steady state and time-resolved emission studies were made on the basis of a theoretical possibility study of proton transfer in the excited state.
Papia Chowdhury, Subhasis Panja, Amrita Chatterjee, Pranab Bhattacharya, Sankar Chakravorti   +4 more
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Benzimidazoles: Veterinary uses

Parasitology Today, 1990
Benzimidazoles are valued for use against helminth infections in domestic animals. Here, Bill Campbell discusses efficacy, dosages, methods of administration and the species of parasite against which they are applied.
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Mode of action of benzimidazoles

Parasitology Today, 1990
Benzimidazoles represent the only class of truly broad-spectrum anthelmintics, however, they also show activity against fungi and mammalian cells. This raises the question as to why benzimidazoles can selectively kill helminths and yet exhibit little or no mammalian toxicity.
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