Results 91 to 100 of about 9,350 (208)
The graphical abstract indicates various photo‐ and photoelectrochemical green methods to produce hydrogen energy using MOF‐based assemblies. Different aspects of MOFs, including organic linkers, metal nodes and their advantage as guest support, are explored thoroughly.
Muhammad Ashraf +16 more
wiley +1 more source
Nitazenes are increasingly present in the illicit drug supply, complicating harm reduction efforts. We have developed a rapid, nontargeted precursor ion scan method to detect emerging nitazenes in real‐world opioid samples. The method identified multiple nitazenes, often replacing pharmaceutical opioids or mixed with fentanyl and benzodiazepines ...
Allie Miskulin +6 more
wiley +1 more source
A laccase–mediator system based on caffeic acid for the synthesis of benzimidazoles
In this study, a laccase–mediator system utilizing caffeic acid as a mediator was developed for the green synthesis of benzimidazole derivatives. The reactions were carried out under mild conditions at room temperature, using citrate buffer as the ...
Mansour Shahedi +3 more
doaj +1 more source
Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms
ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino +3 more
wiley +1 more source
For three collections of Irish Pyrenopeziza brassicae populations fungicide sensitivity status to methyl benzimidazole carbamate (MBC), quinone outside inhibitor (QoI) and succinate dehydrogenase inhibitor (SDHI) fungicides was determined using sensitivity screening in vitro. Molecular mechanisms of insensitivity have been identified for MBC and QoI in
Diana E Bucur +3 more
wiley +1 more source
Winter oilseed rape in Europe suffers frequent pathogen losses. This review outlines key integrated pest management (IPM) strategies, rotation, residue and tillage management, optimized sowing, resistance, and targeted fungicides supported by forecasting.
Jon S West +2 more
wiley +1 more source
Anthelmintic resistance in sheep nematodes in Australia: a compilation of recent test results
Objective The results of recent faecal egg count reduction tests (FECRTs) were collated to provide an indication of the prevalence and severity of anthelmintic resistance in sheep nematodes across Australia and of changes in comparison to earlier testing reports.
RB Besier, NM Rolls
wiley +1 more source
Direct Access to Chiral Piperidines by Enantioselective HAT‐Initiated C(sp3)─H Oxidation
The direct desymmetrization of piperidines is achieved through manganese‐catalyzed enantioselective α‐C(sp3)─H oxidation with hydrogen peroxide, affording versatile chiral N,O‐acetals in good yields and with high enantio‐ and diastereoselectivity. These intermediates provide access to diverse functionalized piperidines with retention of chirality ...
Sethuraman Muthuramalingam +5 more
wiley +2 more sources
ABSTRACT Fatty acid oxidation (FAO) is a metabolic vulnerability in cancer cells, making pharmacologic FAO inhibition a promising therapeutic strategy. This Phase I, open‐label, 3 + 3 dose‐escalation study evaluated the safety, tolerability, pharmacokinetics, and preliminary antitumor activity of two oral FAO inhibitors—omeprazole (KN510), a carnitine ...
Wonyoung Choi +11 more
wiley +1 more source
Application of the fungicide Switch 62.5 WG in garden strawberry (Fragaria × ananassa), targeting Botrytis cinerea, reduced sawfly (Cladius spp.) herbivory by up to 94% and improved fruit quality. This non‐target effect also spilled over to neighbouring untreated plants, lowering damage by 46%.
Esther Kuper +4 more
wiley +1 more source

