Flavin Catalysts in Organic Synthesis
Flavins and their congeners are potent catalysts for organic synthesis inspired by enzymatic transformations. In addition to catalysis in the flavin ground state via covalent intermediates, the excited singlet and triplet states unlock applications including photooxidation, photoreduction, and energy transfer via sensitization.
Jan Freudenberg, Golo Storch
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<i>Loa loa</i> Encephalopathy Following Treatment With Benzimidazole Derivatives: A Systematic Review. [PDF]
Davi SD +10 more
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Facile one pot synthesis of 2-substituted benzimidazole derivatives under mild conditions by using engineered MgO@DFNS as heterogeneous catalyst. [PDF]
Kusuma S +6 more
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Novel 2-Aryl-1H-Benzimidazole Derivatives and Their Aza-Analogues as Promising Anti-Poxvirus Agents. [PDF]
Manca V +14 more
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Quinoline-imidazole/benzimidazole derivatives as dual-/multi-targeting hybrids inhibitors with anticancer and antimicrobial activity. [PDF]
Diaconu D +4 more
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A practical Pd/C‐catalyzed conversion of primary azides to nitriles was investigated under batch and continuous‐flow conditions. This transformation proceeds via net denitrogenative dehydrogenation without an external carbon source. The addition of methyl acrylate or styrene suppresses the formation of reductive byproducts, providing selective access ...
Naoya Sakurada +8 more
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A metal‐ and oxidant‐free electrochemical multicomponent di‐functionalization strategy that rapidly converts 1,1‐disubstituted alkenes into α‐tertiary primary amines with simultaneous installation of bio‐relevant sulfur or selenium motifs was devised for late‐stage functionalization. ABSTRACT Quaternary carbon centers, especially those bearing nitrogen,
Adrija Ghosh +4 more
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Synthesis, Bioactivity and Molecular Modeling Studies on Benzimidazole Derivatives and Its Isosteres as Potent AChE/BChE and GSK3β Inhibitors for Alzheimer's Disease. [PDF]
Sayar G +5 more
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Pyridyl Methylsulfinyl Benzimidazole Derivatives as Promising Agents against Giardia lamblia and Trichomonas vaginalis. [PDF]
Hernández-Ochoa B +14 more
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Multitarget Drug Design for Cardiovascular Disease: Bridging Chemistry and Medicine
Many pathophysiological pathways associated with cardiovascular diseases involve multiple drug targets. This article reviews recent advances in the development of pharmacological compounds capable of simultaneously modulating multiple mechanisms. Multitarget drugs offer a promising therapeutic approach for complex cardiovascular disorders, including ...
Gyuzel Y. Mitronova +3 more
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