Results 101 to 110 of about 636,119 (261)

Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino   +3 more
wiley   +1 more source

A COMPREHENSIVE REVIEW ON BENZIMIDAZOLE DERIVATIVES AND ITS BIOLOGICAL IMPORTANCE

open access: yes, 2012
Condensation of o-phenylene-diamine with formic acid is used in the synthesis of commercially available benzimidazole. N-riosyldimethyl benzimidazole is the most common benzimidazole compound found in nature, and it functions as an axial ligand for ...
M, SHANKAR
core  

BENZIMIDAZOLE DERIVATIVES WITH POTENTIAL CYTOTOXIC ACTIVITY -SYNTHESIS AND THEIR STRUCTURE-ACTIVITY RELATIONSHIP

open access: yesFUUAST Journal of Biology, 2013
Benzimidazole is an important class of compounds with a wide spectrum of biological activity. This five membered heterocyclic moiety confer for various biological activities.
ARFA KAMIL   +7 more
doaj  

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli   +5 more
wiley   +1 more source

Band Engineering of Benzothiadiazole‐Derived Metal‐Organic Frameworks for Photocatalytic Organic Transformations

open access: yesNational Materials, EarlyView.
BTID‐functionalized metal‐organic frameworks provide a modular platform for tailoring photocatalytic electronic structures through acceptor‐linker engineering. By correlating band alignment, charge‐transfer characteristics, and reactive oxygen species generation, this review highlights design principles that enable efficient visible‐light‐driven ...
Xin Li   +3 more
wiley   +1 more source

Applicability of a Simple Decay Function to Describe Fire‐Protective Fabrics' Aging Behavior

open access: yesJournal of Polymer Science, EarlyView.
The simple decay function offers a mean to quantitatively analyze and contrast the aging behavior of various fire‐protective fabrics under a wide range of aging conditions. ABSTRACT Predicting the effect of aging conditions on materials' performance is a challenging yet critical task.
Patricia I. Dolez   +3 more
wiley   +1 more source

Sensitivity of Irish Pyrenopeziza brassicae populations to methyl benzimidazole carbamate (MBC), quinone outside inhibitor (QoI) and succinate dehydrogenase inhibitor (SDHI) fungicides

open access: yesPest Management Science, EarlyView.
For three collections of Irish Pyrenopeziza brassicae populations fungicide sensitivity status to methyl benzimidazole carbamate (MBC), quinone outside inhibitor (QoI) and succinate dehydrogenase inhibitor (SDHI) fungicides was determined using sensitivity screening in vitro. Molecular mechanisms of insensitivity have been identified for MBC and QoI in
Diana E Bucur   +3 more
wiley   +1 more source

Disease control in oilseed rape: Current insights and perspectives for next‐generation integrated pest management

open access: yesPest Management Science, EarlyView.
Winter oilseed rape in Europe suffers frequent pathogen losses. This review outlines key integrated pest management (IPM) strategies, rotation, residue and tillage management, optimized sowing, resistance, and targeted fungicides supported by forecasting.
Jon S West   +2 more
wiley   +1 more source

Synthesis and structural characterization of 1,2-disubstituted benzimidazole derivatives

open access: yes
U ovom radu opisana je sinteza novih derivata benzimidazola supstituiranih u položaju 1 triazolnim supstituentima i u položaju 2 arilnim supstituentima (9-16).
Jeftimija, Maria
core   +3 more sources

Synthesis and anti-Alzheimer activity of new N-(5, 6-dimethyl-1H-benzo[d] imidazol-2-yl)-1-phenylmethanimine derivatives

open access: yesJournal of Advanced Pharmaceutical Technology & Research
The cholinesterase group, including acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), is responsible for inhibiting the actions of choline esters.
Hiba Ali Hasan   +2 more
doaj   +1 more source

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