Results 281 to 290 of about 25,772 (306)

Dimethylidynemerocyaninocyanines ? substituted benzimidazole derivatives

Chemistry of Heterocyclic Compounds, 1984
Dimethylidynemerocyaninocyanines — substituted benzimidazole derivatives — were synthesized. A decrease in the basicity of the benzimidazole ring with intensification of the electronegative properties of the substituent gives rise to a small (up to 10 nm) heightening of the color of the dyes obtained.
R. A. Gershtein, Yu. M. Karpova, E. B. Lifshits, M. S. Lyubich, L. V. Zhirova, S. M. Larina, L. N. Yashukova   +6 more
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The mutagenicity of benzimidazole and benzimidazole derivatives

Analytical Biochemistry, 1973
Abstract The mutagenicity of benzimidazole has been attributed to base substitutions. These were believed to be the result of a small incorporation of benzimidazole—instead of a natural base—into nucleic acids. By using a new indirect method of radioactive labelling it has been possible to prove that benzimidazole is incorporated as such. This method
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Hypoglycemic Potential of Benzimidazole Derivatives

Pharmaceutical Chemistry Journal, 2015
Benzimidazole derivatives exhibiting hypoglycemic and antidiabetic properties were reviewed. Activities of compounds from 22 classes of substituted benzimidazoles and their tricyclic condensed analogs were presented. The structures of compounds acting on various diabetic targets were discussed with respect to antidiabetic activity.
K. V. Lenskaya, Alexander A. Spasov, P. M. Vasil’ev   +2 more
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The mutagenicity of benzimidazole and benzimidazole derivatives. VI. Cytogenetic effects of benzimidazole derivatives in the bone marrow of the mouse and the chinese hamster

Mutation Research/Genetic Toxicology, 1976
Methyl benzimidazole-2-ylcarbamate (MBC) was mutagenic in mice by the micro-nucleus test. Other benzimidazole derivatives, with the exception of the parent compound of MBC, benomyl, and the very closely related substance 2-benzimidazolylurea, did not produce micro-nuclei in mouse bone marrow.
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The mutagenicity of benzimidazole and benzimidazole derivatives I. Forward and reverse mutations in Salmonella typhimurium caused by benzimidazole and some of its derivatives

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1972
Abstract Benzimidazole and a number of derivatives have been found to induce forward mutations using l -azetidine carboxylic acid as the selective agent in Salmonella typhimurium . The analysis of the reversion of several different histidine-requiring mutants to histidine autotrophy under the influence of benzimidazole revealed that the mutagenic ...
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Imidazole and Benzimidazole Derivatives as Chemotherapeutic Agents

Mini-Reviews in Medicinal Chemistry, 2005
Imidazole and benzimidazole systems are presented in a large number of common therapeutics agents. They were widely used in organic and medicinal chemistry, but recently the development of N-oxide derivatives got an improvement from the point of view of its chemical and biological activity.
Mercedes González, Mariana Boiani
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ChemInform Abstract: SYNTHESIS AND STUDY OF SOME BENZIMIDAZOLE DERIVATIVES. VII. PHENOTHIAZINE DERIVATIVES OF BENZIMIDAZOLE

Chemischer Informationsdienst, 1977
AbstractBenzimidazolyl‐äthylamine (I) bzw. Benzimidazole (IV) reagieren mit Phenothiazinyl‐propylchloriden (II) in Gegenwart von Kaliumjodid/Kaliumcarbonat zu den Aminen (III) bzw. den disubstituierten Propanen (V) (Ausbeute 30 ‐ 80%).
L. S. Rogova, L. P. Grebenshchikova, T. M. Vysokovskii, V. M. Kurilenko, N. A. Mukhina, V. M. Pechenina   +5 more
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Antimicrobial Potential of Benzimidazole Derived Molecules

Mini-Reviews in Medicinal Chemistry, 2019
Structural resemblance of benzimidazole nucleus with purine nucleus in nucleotides makes benzimidazole derivatives attractive ligands to interact with biopolymers of a living system. The most prominent benzimidazole compound in nature is N-ribosyldimethylbenzimidazole, which serves as an axial ligand for cobalt in vitamin B12.
Yogita Bansal, Gulshan Bansal, Manjinder Kaur   +2 more
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Comparative Experimental Pharmacokinetics of Benzimidazole Derivatives

Bulletin of Experimental Biology and Medicine, 2008
Comparative study of experimental kinetics of distribution of benzimidazole derivatives (bemithyl, etomerzole, and thietazole) in organs and tissues was carried out after single and course treatment. The drugs intensely passed into organs and tissues from the blood after treatment by all protocols.
I. L. Gulyaeva, S. A. Sergeeva
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ChemInform Abstract: BENZIMIDAZOLE DERIVATIVES WITH ZWITTER‐ION STRUCTURE

Chemischer Informationsdienst, 1975
2-Pyridinium and β- and γ-picolinium-5,6-dinitrobenzimidazole betaines were obtained by reaction of 5,6-dinitro-2-chlorobenzimidazole with pyridine and β- and γ-picolines.
M. A. Kosareva, I. Ya. Postovskii, V. P. Mamaev, O. A. Zagulyaeva, G. A. Mokrushina   +4 more
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