Results 211 to 220 of about 40,476 (314)

Repurposing of FDA‐Approved Drugs to Disrupt Iron Uptake in Mycobacterium abscessus: Targeting Salicylate Synthase as a Novel Approach

open access: yesChemical Biology &Drug Design, Volume 106, Issue 2, August 2025.
A drug repurposing strategy was applied against M. abscessus, through a virtual screening of FDA approved drugs on salicylate synthase. Eleven potential ligands were found; among these, three were confirmed as potent inhibitors of the enzyme. ABSTRACT Non‐tuberculous mycobacteria (NTM) are opportunistic pathogens that lead to severe, persistent ...
Giovanni Stelitano   +7 more
wiley   +1 more source

Structural Origin of Spin‐Orbit Splitting of 1P Orbitals of Icosahedral Au13 Superatom Protected by Ligands

open access: yesAngewandte Chemie, Volume 137, Issue 30, July 21, 2025.
The spin‐orbit (SO) splitting of the superatomic 1P orbitals in thiolate‐protected Au13 superatoms were investigated. Cryogenic anion photoelectron spectroscopy and fully relativistic calculation including SO coupling revealed the 1P orbitals of the Au13 and Au@Ag12 superatomic cores undergo SO splitting, while not in the Ag13 core.
Shun Ito   +2 more
wiley   +2 more sources

Responding to reports of nitazene toxicity in Australia

open access: yes
Medical Journal of Australia, Volume 222, Issue 5, Page 216-219, March 2025.
Brendan Clifford   +5 more
wiley   +1 more source

Fine‐Tuning the Motion of Tetrafluoro‐1,4‐Benzoquinone within Charge‐Transfer Cocrystals Through Variation of the Donor: An Entropic and Enthalpic Point of View

open access: yesChemistry – A European Journal, Volume 31, Issue 42, July 25, 2025.
Five CT cocrystals using TFBQ and fused, polycyclic donors derived from fluorene are synthesized. The π‐stacking in all cocrystals provides a platform for the displaying of in‐plane molecular motions of TFBQ, which is by supramolecular interactions.
Armando Navarro‐Huerta   +7 more
wiley   +1 more source

Impact of the Substitution Pattern in N–heterocyclic Olefin‐Substituted Phosphines on Palladium Catalysis

open access: yesAdvanced Synthesis &Catalysis, Volume 367, Issue 13, July 23, 2025.
The impact of olefin backbone substitution in N‐heterocyclic olefin‐substituted phosphines is investigated. While these ligands are highly electron‐donating, their catalytic activity in Pd‐catalyzed CN cross‐coupling reactions decreases as the size of the backbone substituent increases.
Nicolas Kaiser   +3 more
wiley   +1 more source

New Benzimidazole 3'-Deoxynucleosides: Synthesis and Antiherpes Virus Properties. [PDF]

open access: yesBiomolecules
Arnautova AO   +19 more
europepmc   +1 more source

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