Results 91 to 100 of about 138,894 (338)

Simultaneous Antidepressant and Benzodiazepine New Use and Subsequent Long-term Benzodiazepine Use in Adults With Depression, United States, 2001-2014

JAMA psychiatry, 2017
Importance Benzodiazepines have been prescribed for short periods to patients with depression who are beginning antidepressant therapy to improve depressive symptoms more quickly, mitigate concomitant anxiety, and improve antidepressant treatment ...
G. Bushnell, T. Stürmer, B. Gaynes, V. Pate, Matthew Miller   +4 more
semanticscholar   +1 more source

Crystal structure of 1,5-diethyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dithione

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C13H16N2S2, the seven-membered ring adopts a boat conformation, with the two phenylene C atoms representing the stern and the methylene C atom as the prow. The thione S atoms and N-bound ethyl groups lie on the opposite side of the
Abderrahman Lamkaddem, Mohamed Harcharras, Abdelillah Shaim, Hafid Zouihri, Bousselham Echchahed, Wenhua Bi   +5 more
doaj   +1 more source

Former heroin-dependent alcohol use disorder patients. prevalence, addiction history and clinical features [PDF]

, 2015
Aims: To examine the prevalence of former heroin dependence (FHA) in Alcohol Use Disorder (AUD) patients; to compare the clinical characteristics of FHA-AUD patients versus AUD patients without any past use of heroin at alcohol treatment entry; to ...
Ceccanti, Mauro, Maremmani, Angelo Giovanni Icro, Maremmani, Icro, Pacini, Matteo   +3 more
core   +1 more source

Comprehensive Qualitative Drug Screening in Emergency Toxicology Using an Automated LC–MSn System:Simultaneous Quantification of Relevant Drugs and Metabolites in Blood Plasma

Drug Testing and Analysis, EarlyView.
Simultaneous qualitative and quantitative analysis of 62 drugs and seven active metabolites in human blood plasma by automated liquid chromatography linear ion trap mass spectrometry. ABSTRACT Rapid and comprehensive qualitative and quantitative analytical procedures are crucial in 24/7 emergency toxicology (ET) to support diagnosis and treatment of ...
Selina Hemmer, Maximilian Ninnig, Lea Wagmann, Sascha K. Manier, Markus R. Meyer   +4 more
wiley   +1 more source

Rapid and Simple Dispersive Liquid–Liquid Microextraction (DLLME) Sample Preparation for Propofol Analysis in Hair, Blood, and Urine by Gas Chromatography–Mass Spectrometry

Drug Testing and Analysis, EarlyView.
Development and validation of an extraction method based on dispersive liquid–liquid microextraction for the analysis by GC–MS of propofol in three different biological samples (blood, urine, and hair). The proposed method is very simple and rapid.
Sara Odoardi, Serena Mestria, Valeria Valentini, Giulia Biosa, Sabina Strano Rossi   +4 more
wiley   +1 more source

Patient anxiety and modern elective surgery: a literature review [PDF]

, 2003
Medical advances have led to a considerable rise in the level of elective surgery undertaken as day-case surgery and with minimal hospital stay. However, amid such advances, preoperative psychological care has remained relatively static.
Mitchell, MJ
core   +1 more source

Workplace Drug Testing—Prevalence of Positive Test Results, Most Common Substances, and Importance of Medical Review

Drug Testing and Analysis, EarlyView.
Among 23,900 urine and oral fluid drug tests from Swedish workplaces, 4.6% tested positive for controlled substances. Cannabis, amphetamine, cocaine and benzodiazepines were most common. Many samples containing opiates, amphetamine or benzodiazepines were MRO verified as being due to medical prescriptions, while cannabis or cocaine were almost entirely
Anders Helander, Fredrik Sparring
wiley   +1 more source

The relationship between self-reported substance use and psychiatric symptoms in low-threshold methadone maintenance treatment clients

Harm Reduction Journal, 2011
Background Ongoing psychiatric symptoms and substance use are common difficulties experienced by clients enrolled in methadone maintenance treatment (MMT).
Barrett Sean P, Fulton Heather G, MacIsaac Cindy, Stewart Sherry H   +3 more
doaj   +1 more source

Neuroactive steroids in depression and anxiety disorders: Clinical studies [PDF]

, 2006
Certain neuroactive steroids modulate ligand-gated ion channels via non-genomic mechanisms. Especially 3 alpha-reduced pregnane steroids are potent positive allosteric modulators of the gamma-aminobutyric acid type A (GABA(A)) receptor.
Akwa Y, Baghai TC, Baker ER, Barrett-Connor E, Bicikova M, Bitran D, Bloch M, Brambilla F, Brambilla F, Brambilla F, Cornelius Schüle, Crawley JN, Dalton K, Daniela Eser, Dennerstein L, Dong E, Elena Romeo, Eser D, Evans RM, Fabian TJ, Freeman E, Freeman EW, Friess E, George MS, Goodyer IM, Guidotti A, Heydari B, Heydary B, Kita A, Koszycki D, Lawrie TA, Maayan R, Magill PJ, Majewska MD, Majewska MD, Majewska MD, Matsumoto K, Meieran SE, Melchior CL, Melchior CL, Mensah-Nyagan AG, Mienville JM, Monnet FP, Padberg F, Papadopoulos V, Paul SM, Purdy RH, Rainer Rupprecht, Reddy DS, Reddy DS, Reddy DS, Rodgers RJ, Romeo E, Rupprecht R, Rupprecht R, Schmidt PJ, Schule C, Schule C, Semeniuk T, Serra M, Serra M, Strohle A, Strohle A, Strohle A, Strous RD, Takebayashi M, Thomas C. Baghai, Tollefson GD, Trauger JW, Urani A, Uzunov DP, Uzunova V, Uzunova V, Uzunova V, Vanselow W, Wieland S, Wolkowitz OM, Wolkowitz OM, Wu FS, Zwanzger P   +79 more
core   +1 more source

Screening and Quantification of the Synthetic Cannabinoid Receptor Agonist 5F‐MDMB‐PINACA From Seized Prison Paper Using Ultraperformance Liquid Chromatography–Mass Spectrometry Approaches

Drug Testing and Analysis, EarlyView.
Synthetic cannabinoid receptor agonists are being infused on paper and illicitly introduced into prisons through mail correspondence. An approach to quantify and map the synthetic cannabinoid 5F‐ADB on a seized paper sample from a UK prison was determined using ultraperformance liquid chromatography–quadrupole Dalton–mass spectrometry.
Giorgia Vaccaro, Jacqueline L. Stair, Stewart B. Kirton, Daniel Baker, Amira Guirguis   +4 more
wiley   +1 more source