Results 121 to 130 of about 211,779 (381)

Progress of non‐motor symptoms in early‐onset Parkinson's disease

Ibrain, EarlyView.
This study reviews the research progress related to non‐motor symptoms (NMS) in patients with early onset Parkinson's disease (EOPD), including neuropsychiatric symptoms, autonomic dysfunction, sleep disorders, and sensory disorders and also summarizes the characteristics of NMS in the genetic form of Parkinson's disease (PD).
Fanshi Zhang, Aidi Luo, Shusheng Liao, Mei Liu, Jun Zhang, Zucai Xu   +5 more
wiley   +1 more source

Benzodiazepines and risk of dementia – Is there a reason for alarm?

European Psychiatry
Introduction The population ageing is a reality associated with an increase in prevalence of Dementia. The use of benzodiazepines is often postulated as a risk factor in these syndromes.
R. P. L. Andrade, N. Castro, R. Vaz, J. Martins, J. Abreu, E. Almeida, I. Santos, F. Cunha, H. Afonso   +8 more
doaj   +1 more source

RESPOND – A patient-centred program to prevent secondary falls in older people presenting to the emergency department with a fall: Protocol for a multi-centre randomised controlled trial [PDF]

, 2014
Introduction: Participation in falls prevention activities by older people following presentation to the Emergency Department (ED) with a fall is suboptimal.
A Forbes, A L Barker, A M Hill, Barlow, Bloch, Bunn, C A Brand, C D Etherton-Beer, Close, D Smit, Davison, de Vries, G Arendts, Gates, Haines, Helbostad, Hendriks, Hill, Hill, Hill, Hill, Hoffmann, Hurst, J A Lowthian, J Redfern, K D Hill, Kempen, L Flicker, Lamb, Lightbody, Mead, N Waldron, Neubeck, Nyman, Nyman, Osborne, P A Cameron, P Hunter, Pardessus, Prince, Redfern, Russell, Russell, Russell, S R Nyman, Samaras, Shaw, Simek, T P Haines, Tidermark, Tombaugh, Vind, Whitehead, Whitehead   +53 more
core   +1 more source

Bifenthrin Under Scrutiny: Revisiting Toxicological Evidence Amid Regulatory Gaps

Journal of Applied Toxicology, EarlyView.
ABSTRACT Despite growing health concerns, bifenthrin (BF) remains widely used for controlling agricultural and residential pests. However, different perspectives on its toxicological profile and regulatory framework warrant a revisit and update on BF regulation towards a robust risk‐safety assessment.
Caroline V. L. Moreira, John Ogbu I, Kadja L. C. Monteiro, Thiago M. de Aquino, Edeildo F. da Silva‐Júnior, Alberto S. S. Filho, Hamilton B. Napolitano, Christianah A. Elusiyan, Renê O. do Couto, Elson A. Costa, James O. Fajemiroye   +10 more
wiley   +1 more source

Is there a potential of misuse for Magnolia officinalis compounds/metabolites? [PDF]

, 2017
© 2017 John Wiley & Sons, Ltd.Objective: Magnolia bark contains magnolol, metabolized to tetrahydromagnolol and honokiol, with both GABA-ergic/cannabimimetic activities, hence of possible attraction to vulnerable individuals/recreational misusers ...
Alexeev, Böhmdorfer, Chiou, Coppola, Fattore, Fuchs, Fuchs, Garrison, Hattori, Kalman, Kao, Kotani, Kuribara, Lee, Lee, Lin, Liu, Mantani, Nakazawa, Oikawa, Papanti, Rempel, Schifano, Schifano, Schifano, Siemann, Sohn, Squires, Tsai, Tsai, Wang, Watanabe, Xu   +32 more
core   +3 more sources

Use of benzodiazepines and related drugs in Manitoba: a population-based study.

CMAJ Open, 2014
BACKGROUND Despite their favourable toxicology profile, benzodiazepines and the related Z-drugs (zopiclone, zolpidem and zaleplon) have been associated with physiological tolerance, dependence and addiction.
S. Alessi-Severini, J. Bolton, M. Enns, Matthew Dahl, D. Collins, D. Chateau, J. Sareen   +6 more
semanticscholar   +1 more source

Exogenous Melatonin and Sleep Quality: A Scoping Review of Systematic Reviews

The Journal of Clinical Pharmacology, EarlyView.
Abstract Melatonin is increasingly used to treat sleep disturbances, yet its overall efficacy remains unclear due to variability in existing evidence. This scoping review aimed to synthesize systematic reviews with meta‐analyses assessing the effects of exogenously administered melatonin on sleep quality in humans.
Samyuktha Iyer, Vaneesha Monk, Rebeccah Slater, Luke Baxter   +3 more
wiley   +1 more source

Electrochemical oxidation of psychoactive compounds using RuO2/IrO2 electrodes: impacts on neuronal activity and water matrix influence

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND This study focuses on utilizing the electrochemical oxidation (EO) process to eliminate psychoactive substances and aims to assess the impact of EO‐treated water on the neuronal activity of rat hippocampus (specifically the CA3 region).
Enrico Mendes Saggioro, Bianca Miguel de Souza‐Chaves, Morgana Bosio, Maria Emília Quinta‐Ferreira, Rosa Quinta‐Ferreira, Márcia Dezotti   +5 more
wiley   +1 more source

Valproate-Enhanced Protocols for Alcohol Withdrawal Syndrome: A Brief Review and Retrospective Study of Efficacy and the Ability to Reduce Benzodiazepine Use

Pharmaceuticals
Background: Although benzodiazepines are the first-line treatment for alcohol withdrawal syndrome (AWS), their use may pose significant risks, including oversedation and the potential for misuse, particularly in vulnerable populations such as individuals
Simone Pardossi, Alessandro Cuomo, Giacomo Gualtieri, Mario Pinzi, Giuditta Piumini, Andrea Fagiolini   +5 more
doaj   +1 more source

Safety of MRI Examinations Under Sedation: A Nationwide Survey in Japan

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background MRI is performed under sedation for patients requiring immobility or for those already sedated for clinical management. Although specialist guidelines advocate for anesthesiologist‐led care, non‐anesthesiologist‐led adult sedation is a common practice worldwide. Furthermore, the increase in risk attributable to sedation has not been
Shiori Amemiya, Masako Kataoka, Tsukasa Doi, Toshinori Hirai, Takayuki Obata, Kagayaki Kuroda   +5 more
wiley   +1 more source