A Study on Comparison of Two Benzodiazepines in Treatment of Alcohol Dependence Syndrome in Nepal
Journal of Nobel Medical College, 2022 Background: Benzodiazepines are regularly prescribed to treat patients in alcoholic withdrawal. After analyzing pharmacology of benzodiazepines, diazepam is faster metabolized and concentrated in the liver, as an active metabolite whereas lorazepam is ...
Vijay Kaul +3 more
doaj +1 more source
Deprescribing zolpidem reduces falls and fractures in patients with cirrhosis
JHEP Reports, 2022 Background & Aims: Benzodiazepines are associated with an increased risk of harm in patients with cirrhosis. However, stopping benzodiazepines must be done with care to avoid withdrawal or other unintended consequences. The impact of deprescribing on
Elliot B. Tapper +3 more
doaj
Clozapine prescribing patterns in hospitalised patients in everyday clinical practice
Open Journal of Psychiatry and Allied Sciences, 2020 Aim: Clozapine is the gold standard for treatment-resistant schizophrenia. Despite clear recommendations for use, under-use and excessive delay in the use of clozapine are an ongoing findings in the literature.
Ivana Stašević Karličić +3 more
doaj +1 more source
Influence of glutamatergic and GABAergic neurotransmission on obstructive sleep apnea
Frontiers in Neuroscience, 2023 Glutamate and γ-aminobutyric acid (GABA) are the two main neurotransmitters in the human brain. The balance between their excitatory and inhibitory functions is crucial for maintaining the brain’s physiological functions.
Piotr Kaczmarski +4 more
doaj +1 more source
Vìsnik Odesʹkogo Nacìonalʹnogo Unìversitetu: Hìmìâ, 2014 By the reaction of 7-bromo-5-aryl-1,2-dihydro-3H-1,4-benzodiazepine-2-ones with Lawesson reagent, 7-bromo-5-aryl-1,2-dihydro-3H-1,4-benzodiazepine-2-tiones were synthesized from which 3-arylidene-7-bromo-2-hydrazino-5-phenyl-3H-1,4-benzodiazepines were ...
V. I. Pavlovsky +2 more
doaj +1 more source
Psychogenic coma after general anesthesia with remimazolam and remifentanil -a case report- [PDF]
Korean Journal of Anesthesiology, 2022 Background Delayed emergence from general anesthesia is associated with life-threatening conditions with pharmacological, neurological, metabolic, and rarely, psychiatric causes.
Song Hyun Kim +5 more
doaj +1 more source
Estimating Heterogeneous Causal Effect of Polysubstance Usage on Drug Overdose from Large-Scale Electronic Health Record [PDF]
arXiv, 2021 Drug overdose has become a public health crisis in the United States with devastating consequences. However, most of the drug overdose incidences are the consequence of recitative polysubstance usage over a defined period of time which can be happened by either the intentional usage of required drug with other drugs or by accident. Thus, predicting the
arxiv
The Impact of Opioid Prescribing Limits on Drug Usage in South Carolina: A Novel Geospatial and Time Series Data Analysis [PDF]
arXiv, 2023 Background: To curb the opioid epidemic, legislation regulating the amount of opioid prescriptions covered by Medicaid (Title XIX of the Social Security Act Medical Assistance Program) came into effect in May 2018 in South Carolina. Methods: We employ a classification system based on distance and disparity between dispensers, prescribers, and patients ...
arxiv
BMC Family Practice, 2005 Background Over-prescribing of benzodiazepines appears common in many countries, a better understanding of prescribing practices and attitudes may help develop strategies to reduce prescribing.
Critchley Julia +3 more
doaj +1 more source
ODD: A Benchmark Dataset for the Natural Language Processing based Opioid Related Aberrant Behavior Detection [PDF]
arXiv, 2023 Opioid related aberrant behaviors (ORABs) present novel risk factors for opioid overdose. This paper introduces a novel biomedical natural language processing benchmark dataset named ODD, for ORAB Detection Dataset. ODD is an expert-annotated dataset designed to identify ORABs from patients' EHR notes and classify them into nine categories; 1 ...
arxiv