Results 31 to 40 of about 87,784 (205)

Impact of long‐term management with sleep medications on blood pressure: An Australian national study

open access: yesBrain and Behavior, 2023
Background There is mixed evidence about the impact of long‐term management with hypnotic medications on blood pressure (BP). Aim To estimate the effect of short‐ and long‐term management with benzodiazepine and z‐drugs (BZD) on BP.
Mumtaz Begum   +3 more
doaj   +1 more source

Reversal of a Suspected Paradoxical Reaction to Zopiclone with Flumazenil

open access: yesCase Reports in Critical Care, 2016
We describe the care for an elderly woman who was admitted to the intensive care unit (ICU) to receive noninvasive ventilation for acute exacerbation of chronic obstructive pulmonary disease.
Zarah Jordahn   +3 more
doaj   +1 more source

Prediction of Drug–Drug Interactions Between Opioids and Overdosed Benzodiazepines Using Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation

open access: yesDrugs in R&D, 2019
Background Researchers have long been interested in the potential drug–drug interactions (DDIs) between opioids and benzodiazepines. However, much remains unknown concerning the interactions between these two drug classes.
Beihong Ji   +6 more
doaj   +1 more source

Benzodiazepine abuse among the elderly

open access: yesJournal of Geriatric Mental Health, 2016
Benzodiazepines belong to the hypnotic-sedative class of drugs which have anxiolytic, sedative, and hypnotic properties. These drugs have been in clinical use for at least half a century.
Shalini Singh, Siddharth Sarkar
doaj   +1 more source

Crystal strucutre of rac-methyl (11aR*,12S*,13R*,15aS*,15bS*)-11-oxo-11,11a,12,13-tetrahydro-9H,15bH-13,15a-epoxyisoindolo[1,2-c]pyrrolo[1,2-a][1,4]benzodiazepine-12-carboxylate

open access: yesActa Crystallographica Section E, 2014
The title compound, C21H18N2O4, obtained as a racemate, contains a novel heterocyclic system, viz. isoindolo[1,2-c]pyrrolo[1,2-a][1,4]benzodiazepine. The central diazepane ring has a distorted boat conformation with two phenylene-fused and one methine C ...
Vladimir P. Zaytsev   +4 more
doaj   +1 more source

Baclofen but Not Diazepam Alleviates Alcohol-Seeking Behavior and Hypothalamic–Pituitary–Adrenal Axis Dysfunction in Stressed Withdrawn Mice

open access: yesFrontiers in Psychiatry, 2019
This study compares the impact of repeated injections of baclofen (an agonist of GABAB receptors) or diazepam (a benzodiazepine having an agonist action on GABAA receptors) given during the alcohol-withdrawal period on the stress-induced restoration of ...
Yolaine Rabat   +4 more
doaj   +1 more source

Implementing an Online Program to Change Benzodiazepine Prescription: Protocol of a Hybrid Type 1 Cluster-Randomised Trial

open access: yesPortuguese Journal of Public Health, 2022
Introduction: Excessive benzodiazepine (BZD) prescription has long been considered a serious mental health concern in many countries. Many interventions using different methodologies have been implemented to change BZD prescription patterns in primary ...
Teresa Reis   +3 more
doaj   +1 more source

Is the Long-Term Use of Benzodiazepines Associated With Worse Cognition Performance in Highly Educated Older Adults?

open access: yesFrontiers in Psychiatry, 2020
Background: Benzodiazepines (BZD) are common medications for sedative, hypnotic, and anxiolytic that are especially prevalent in older adults. Previous studies have shown that BZD use could impair users' cognition, significantly affecting their quality ...
Linzi Liu   +10 more
doaj   +1 more source

Benzodiazepines for delirium [PDF]

open access: yesCochrane Database of Systematic Reviews, 2009
Delirium occurs in 30% of hospitalised patients and is associated with prolonged hospital stay and increased morbidity and mortality. The results of uncontrolled studies have been unclear, with some suggesting that benzodiazepines may be useful in controlling non-alcohol related delirium.To determine the effectiveness and incidence of adverse effects ...
Almudena Areosa Sastre   +2 more
openaire   +3 more sources

Effects of Clonidine versus Midazolam premedication on postoperative pain in patients undergoing elective spinal neurosurgery. Prospective randomized study [PDF]

open access: yesRomanian Journal of Medical Practice, 2017
Many preoperative, intraoperative and postoperative interventions and management strategies are available and continue to evolve for reducing and managing postoperative pain.
Ana-Maria Cotae   +6 more
doaj   +1 more source

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