Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Drugs increase the risk of suicide in the elderly
The purpose of this paper is a systematic review of articles and research in the context of drugs used and suicide in elderly patients. Suicide in the elderly may be much more frequent than in the younger population.
Kornelia Kędziora-Kornatowska +6 more
doaj +1 more source
The bridge between classical and ‘synthetic’/chemical psychoses: towards a clinical, psychopathological and therapeutic perspective [PDF]
© 2019 Orsolini, Chiappini, Papanti, De Berardis, Corkery and Schifano. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Chiappini, Stephania +5 more
core +2 more sources
Palliative care for people with non-malignant lung disease: summary of current evidence and future direction [PDF]
Background: The physical and psychosocial needs of patients with chronic non-malignant lung disease are comparable to those with lung cancer. This article will focus on chronic obstructive pulmonary disease, interstitial lung disease and cystic fibrosis ...
Boland, Jason +5 more
core +1 more source
Degradation of 17 Benzodiazepines by the UV/H2O2 Treatment
Benzodiazepines are one group of psychoactive drugs widely detected in water environments, and their persistence during conventional wastewater treatment has raised great concerns. Here we investigated the degradation of 17 benzodiazepines in water by UV/
Wen-Dan You +13 more
doaj +1 more source
Background Over-prescribing of benzodiazepines appears common in many countries, a better understanding of prescribing practices and attitudes may help develop strategies to reduce prescribing.
Critchley Julia +3 more
doaj +1 more source
Effects of Clonidine versus Midazolam premedication on postoperative pain in patients undergoing elective spinal neurosurgery. Prospective randomized study [PDF]
Many preoperative, intraoperative and postoperative interventions and management strategies are available and continue to evolve for reducing and managing postoperative pain.
Ana-Maria Cotae +6 more
doaj +1 more source
Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication. [PDF]
A key goal of diabetes research is to develop treatments to safely promote human ß-cell replication. It has recently become appreciated that activation of γ-aminobutyric acid receptors (GABA-Rs) on ß-cells can promote their survival and replication.
Dang, Hoa +3 more
core +1 more source
Reversal of a Suspected Paradoxical Reaction to Zopiclone with Flumazenil
We describe the care for an elderly woman who was admitted to the intensive care unit (ICU) to receive noninvasive ventilation for acute exacerbation of chronic obstructive pulmonary disease.
Zarah Jordahn +3 more
doaj +1 more source
The Characteristics of Benzodiazepine Prescribing in the Republic of Srpska, Bosnia and Herzegovina
Background and Objectives: Benzodiazepines (BZDs) are among the most prescribed psychotropic drugs and significant number of patients use these drugs for longer periods than recommended. The objective of this study was to determine the factors associated
Žana M. Maksimović +5 more
doaj +1 more source

