Results 71 to 80 of about 207,949 (383)

Effects of Clonidine versus Midazolam premedication on postoperative pain in patients undergoing elective spinal neurosurgery. Prospective randomized study [PDF]

Romanian Journal of Medical Practice, 2017
Many preoperative, intraoperative and postoperative interventions and management strategies are available and continue to evolve for reducing and managing postoperative pain.
Ana-Maria Cotae, Liliana Mirea, Raluca Ungureanu, Ioana Cristina Grintescu, Alexandra Ionescu, Oana Maria Melente, Ioana Marina Grintescu   +6 more
doaj   +1 more source

Synthetic epoxy-pregnan steroids: effects on anxiety behavior in rats [PDF]

, 2016
Neurosteroids like 3α-OH-5α-pregnan-20-one (allopregnanolone) and 3α-OH-5β-pregnan-20-one (pregnanolone) modulate the γ-aminobutyric acid-A (GABAA) receptor function and produce several effects that can be considered for therapeutical pruposes like ...
Coirini, Hector, Ghini, Alberto Antonio, Rey, Mariana   +2 more
core   +1 more source

Prescribed Benzodiazepines and Suicide Risk: A Review of the Literature.

The Primary Care Companion For CNS Disorders, 2017
Objective To evaluate whether prescribed benzodiazepines affect one's risk of suicide. Data Sources A PubMed search of English-language publications from database inception until October 11, 2016, was conducted using the terms benzodiazepine and ...
Tyler J Dodds
semanticscholar   +1 more source

Implementing physician‐led medication reviews for patients with diabetes and severe mental disorder: A randomized controlled trial

British Journal of Clinical Pharmacology, EarlyView.
Aims Patients with severe mental disorder and diabetes may be exposed to inappropriate polypharmacy increasing the risk of side effects and drug interactions. Although medication reviews may facilitate short‐term deprescribing, they are not known to affect clinical outcomes.
Johan Frederik Mebus Meyer Christensen, Signe Wegmann Düring, Gesche Jürgens   +2 more
wiley   +1 more source

Patient, carer and healthcare professional perspectives on deprescribing in surgical wards: A mixed methods study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The perspectives of patients and healthcare professionals regarding deprescribing in surgical wards within hospital settings are unknown. The aim of this study was to explore current practices, attitudes and the enablers and barriers to deprescribing in hospital for older surgical inpatients from the perspectives of doctors, pharmacists ...
Bonnie M. Liu, Janani Thillainadesan, Aili Langford, Kenji Fujita, Danijela Gnjidic, Sarah N. Hilmer   +5 more
wiley   +1 more source

The efficacy of low and moderate dosage of diazepam on sleep bruxism in children: A randomized placebo-controlled clinical trial

Journal of Research in Medical Sciences, 2019
Background: Sleep bruxism (SB) in children is commonly a self-limited problem; however, therapy of the condition may be needed to improve sleep quality of parents and children. Benzodiazepines have some success in controlling adult bruxism. The objective
Seyyed-Nassereddin Mostafavi, Azadeh Jafari, Shervin Ghaffari Hoseini, Majid Khademian, Roya Kelishadi   +4 more
doaj   +1 more source

Is the Long-Term Use of Benzodiazepines Associated With Worse Cognition Performance in Highly Educated Older Adults?

Frontiers in Psychiatry, 2020
Background: Benzodiazepines (BZD) are common medications for sedative, hypnotic, and anxiolytic that are especially prevalent in older adults. Previous studies have shown that BZD use could impair users' cognition, significantly affecting their quality ...
Linzi Liu, Peiying Jian, Yifang Zhou, Yifang Zhou, Jian Zhou, Linna Jia, Minghui Tang, Rongwei Zhang, Rongwei Zhang, Yanqing Tang, Yanqing Tang   +10 more
doaj   +1 more source

Identifying and preventing health problems among young drug-misusing offenders [PDF]

, 2013
Purpose – The purpose of this paper is to identify the health problems and treatment needs of drug-misusing offenders and to draw out the implications of the findings for health education and prevention.
Judith Aldridge, Katy Holloway, Trevor Bennett   +2 more
core   +2 more sources

Contribution of Addictovigilance data to assess adverse‐events linked to psychoactive substances in children and adolescents

British Journal of Clinical Pharmacology, EarlyView.
Aims We sought to characterize adverse events and deaths associated with the use of psychoactive substances in children and adolescents. Methods Two French Addictovigilance databases were analysed: spontaneous reports and deaths over the period 2016–2021, in subjects aged 10–<18 years. An unsupervised classification was implemented on consumption data (
Hélène Peyrière, Anne Batisse, Nathalie Fouilhé Sam‐Laï, Amélie Daveluy, Christine Fournier‐Choma, Sylvie Deheul, Cécile Chevalier, Clémence Lacroix, Valérie Gibaja, Aurélie Aquizerate, Stéphanie Pain, Emilie Jouanjus, Marie‐Christine Picot, Erika Nogue   +13 more
wiley   +1 more source

Metformin, Sulfonylureas, or Other Antidiabetes Drugs and the Risk of Lactic Acidosis or Hypoglycemia [PDF]

, 2011
OBJECTIVE: Lactic acidosis has been associated with use of metformin. Hypoglycemia is a major concern using sulfonylureas. The aim of this study was to compare the risk of lactic acidosis and hypoglycemia among patients with type 2 diabetes using oral ...
Bodmer, Michael, Jick, Susan S., Krähenbühl, Stephan, Meier, Christian, Meier, Christoph R.   +4 more
core   +2 more sources