Results 71 to 80 of about 146,798 (343)
Managing Persistent Radial Artery Spasm During Coronary Catheterization: A Complex Case Study
ABSTRACT This case report details the management of persistent radial artery spasm during coronary catheterization, unresponsive to standard pharmacotherapy. After conventional methods failed, deep sedation, neuromuscular blockade, and orotracheal intubation proved essential.
Riccardo Mager+3 more
wiley +1 more source
Silylation is a widely used derivatization technique for the gas chromatographic analysis of benzodiazepines, a class of psychoactive drugs commonly encountered in forensic and biological samples.
Eleazar Vargas Mena+2 more
doaj +1 more source
Reducing Benzodiazepine Use for the Treatment of Insomnia and Supporting Nonpharmacological Therapies [PDF]
Most medical organizations recommend against the use of benzodiazepine use for the treatment of insomnia, especially in the elderly. However, the percentage of the adult population on benzos increase with age: 7.5% in adults ages 51-64; 9% in adults over
Pyon, UnChan
core +1 more source
Palliative care for people with non-malignant lung disease: summary of current evidence and future direction [PDF]
Background: The physical and psychosocial needs of patients with chronic non-malignant lung disease are comparable to those with lung cancer. This article will focus on chronic obstructive pulmonary disease, interstitial lung disease and cystic fibrosis ...
Boland, Jason+5 more
core +1 more source
We have described the synthesis of a new series of LCAPs (long‐chain arylpiperazine) as serotoninergic ligands (FG 1‐18). The combination of structural elements including heterocyclic nucleus, propyl chain and 4,5‐dihydrothiazol‐2‐ylphenylpiperazines, led to the preparation of different derivatives tested for their affinity toward 5‐HT1A, 5‐HT2A and 5 ...
Giorgia Andreozzi+18 more
wiley +1 more source
The new ionization technique, vacuum‐insulated probe‐heated electrospray, allows for a simple dilute‐and‐shoot sample preparation to be used with liquid chromatography time‐of‐flight mass spectrometry in urine drug screening. Comparison with a method relying on solid‐phase extraction and conventional electrospray ionization shows improved performance ...
Mira Sundström+4 more
wiley +1 more source
Benzodiazepines and Related Drugs as a Risk Factor in Alzheimer's Disease Dementia
Benzodiazepines (BZDs) and Z-drugs are compounds widely prescribed in medical practice due to their anxiolytic, hypnotic, and muscle relaxant properties.
Miren Ettcheto+32 more
doaj +1 more source
Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication. [PDF]
A key goal of diabetes research is to develop treatments to safely promote human ß-cell replication. It has recently become appreciated that activation of γ-aminobutyric acid receptors (GABA-Rs) on ß-cells can promote their survival and replication.
Dang, Hoa+3 more
core +1 more source
Exploring the baseline knowledge and experience of healthcare professionals in the United Kingdom on Novel Psychoactive Substances [PDF]
Submitted 28 january 2020. Reviwers' comments received 11 February 2020. Accepted 26 February 2020. Published 2 March 2020.Objective: This survey aimed to explore knowledge and experience on novel psychoactive substances (NPS) of healthcare professionals
Bancroft, Angus+9 more
core +3 more sources
Simultaneous qualitative and quantitative analysis of 62 drugs and seven active metabolites in human blood plasma by automated liquid chromatography linear ion trap mass spectrometry. ABSTRACT Rapid and comprehensive qualitative and quantitative analytical procedures are crucial in 24/7 emergency toxicology (ET) to support diagnosis and treatment of ...
Selina Hemmer+4 more
wiley +1 more source