Comparative Hepatoprotective Effects of Esculetin and Its Derivatives Against Oxidative Stress [PDF]
AntioxidantsIn this study, we evaluated the antioxidant activities of esculetin and four synthesized derivatives (E1, 2-oxo-2H-1-benzopyran-6,7-diyl diacetate; E2, 7-hydroxy-2-oxo-2H-1-benzopyran-6-yl acetate; E3, 7-(methoxymethoxy)-2-oxo-2H-1-benzopyran-6-yl ...
Yoonjeong Kim +4 more
doaj +2 more sources
Recent advances in the structures and bioactivities of benzopyrans derived from marine fungi: a review [PDF]
Frontiers in PharmacologyMarine fungi represent a treasure trove of bioactive secondary metabolites, with benzopyran compounds emerging as a significant class of these natural products.
Yidan Xi +6 more
doaj +2 more sources
The Antimicrobial and Cytotoxicity Properties of New Dibrominated 1,3-Dithiolium Flavonoids [PDF]
PharmaceuticalsBackground/Objectives: Antimicrobial resistance (AMR) presents a medical risk as well as a significant global socioeconomic challenge. Key contributors to AMR include the excessive use and incorrect application of antibiotics in humans and agriculture ...
Laura Gabriela Sarbu +6 more
doaj +2 more sources
A Structure–Activity Relationship Study on the Antioxidant Properties of Dithiocarbamic Flavanones [PDF]
AntioxidantsThe antioxidant properties of 3-dithiocarbamic flavanones have been investigated. The influence of the halogen substituents on ring A of the flavanones and the nature of the secondary amine from the dithiocarbamic moiety have been accounted.
Mihail Lucian Birsa +1 more
doaj +2 more sources
Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancer
Journal of Enzyme Inhibition and Medicinal Chemistry, 2023 Structural tailoring of the flavone framework (position 7) via organopalladium-catalyzed C–C bond formation was attempted in this study. The impact of substituents with varied electronic effects (phenyl ring, position 2 of the benzopyran scaffold) on the
Sachin Sharma +11 more
doaj +1 more source
Synergistic effect of natural chickpea leaf exudates acids in heterocyclization: a greener protocol for benzopyran synthesis [PDF]
Royal Society Open Science, 2018 Without using any toxic or hazardous reagent, ligand, acid, transition metal catalyst, additives/promoters and organic solvent, green Knoevenagel condensation and tandem Knoevenagel–Michael reactions have been successfully carried out by using chickpea ...
Snehali Mali +3 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2021 Inhibition of the insulin-regulated aminopeptidase (IRAP) improves memory and cognition in animal models. The enzyme has recently been crystallized and several series of inhibitors reported.
Sudarsana Reddy Vanga +4 more
doaj +1 more source
Essential Rule Derived from Thermodynamics and Kinetics Studies of Benzopyran Compounds
Molecules, 2023 Compounds with benzopyran as the core structure play an important role in the total synthesis of antioxidants, drugs, and natural products. Herein, the thermodynamic data of benzopyran compounds and their intermediates were measured and calculated by ...
Baolong Chen, Xin Hu, Xiaoqing Zhu
doaj +1 more source
Molecules, 2020 Construction of a focused library of polycyclic ether-benzopyrans was undertaken in order to discover new therapeutic compounds that affect Leishmania growth and infectivity.
Sarita Singh +6 more
doaj +1 more source
Synthesis and characterization of new 2-amino-4-(substituted phenyl)-6-(7’’-methoxy, 3’’,4’’-dihydro, 2’’,2’’-dimethyl-2hbenzopyran) pyrimidines and their bio evaluation [PDF]
Journal of the Serbian Chemical Society, 2012 A series of eight novel 2-amino-4-(substituted phenyl)-6-(7"- methoxy, 3",4"-dihydro, 2",2"-dimethyl-2H-benzopyran) pyrimidines were designed and synthesized by utilizing benzene-1,3-diol as starting material.
Murthy Y.L.N. +2 more
doaj +1 more source