Results 31 to 40 of about 16,857 (213)

Cytochrome P450 Can Epoxidize an Oxepin to a Reactive 2,3-Epoxyoxepin Intermediate: Potential Insights into Metabolic Ring-Opening of Benzene

Molecules, 2020
Dimethyldioxirane epoxidizes 4,5-benzoxepin to form the reactive 2,3-epoxyoxepin intermediate followed by very rapid ring-opening to an o-xylylene that immediately isomerizes to the stable product 1H-2-benzopyran-1-carboxaldehyde.
Holly M. Weaver-Guevara, Ryan W. Fitzgerald, Noah A. Cote, Arthur Greenberg   +3 more
doaj   +1 more source

Efficient and Mild Microwave-Assisted Stepwise Functionalization of Naphthalenediimide with α-Amino Acids [PDF]

, 2006
Microwave dielectric heating proved to be an efficient method for the one-pot and stepwise syntheses of symmetrical and unsymmetrical naphthalenediimide derivatives of α-amino acids.
Otto, Sijbren,, Pantoş, G. Dan,, Pengo, Paolo,, Sanders, Jeremy K.M.,   +3 more
core   +4 more sources

Antibacterial and Antifungal Properties of New Synthetic Tricyclic Flavonoids

Antibiotics
Background/Objectives: The discovery of new molecules to which bacteria have not yet developed resistance is a significant medical priority. Synthetic flavonoids are good candidates for developing new antimicrobials.
Laura Gabriela Sarbu, Irina Rosca, Mihail Lucian Birsa   +2 more
doaj   +1 more source

Potential mosquito repellent compounds of Ocimum species against 3N7H and 3Q8I of Anopheles gambiae [PDF]

, 2016
Mosquitoes are exceptionally efficient in detecting their hosts for blood meal using odorant binding proteins, viz. 3N7H and 3Q8I and spread several dreadful diseases.
Allu Prasada Rao, Talluri Venkateswara Rao, Venugopal Gaddaguti   +2 more
core   +1 more source

Methyl 2-oxo-2H-chromene-3-carboxylate [PDF]

, 2012
The title compound, C11H8O4, features an almost planar molecule (r.m.s. deviation = 0.033 Å for all non-H atoms). In the crystal, the molecules are linked via C-H...O hydrogen bonds, forming two-dimensional networks lying parallel to (1-21)
Arshad, Muhammad, Bolte, Michael, Ibrar, Aalia, Saeed, Aamer   +3 more
core   +2 more sources

Targeting the Membrane‐Embedded Rhomboid Protease GlpG: A Multimodal Strategy for Inhibitor Discovery and Mechanistic Insight

Angewandte Chemie, Volume 138, Issue 10, 2 March 2026.
Created in BioRender. Bohg, C. (2026) https://BioRender.Com/ vi9hi4f. Rhomboid proteases are a mechanistically unique and evolutionarily conserved protein family. Despite their pharmacological relevance, the development of selective inhibitors has lagged behind that of soluble proteases.
Claudia Bohg, Yurii Dubanych, Spyridon Kosteletos, Taoran Xiao, Martin Neuenschwander, Tillmann Utesch, Michael Lisurek, Carl Öster, Andreas Oder, Carola Seyffarth, Kathrin Bach, Denise‐Liù Gracias Leone, František Filandr, Marc Wegert, Sascha Lange, Henry Sawczyc, Jens Peter von Kries, Christian P. R. Hackenberger, Edgar Specker, Han Sun, Kvido Stříšovský, Adam Lange   +21 more
wiley   +2 more sources

Chirale Lactole, IV. Selektivitäten bei Acetalisierungsreaktionen enantiomerenreiner Lactole am Beispiel von Octahydro-8,9,9-trimethyl-5,8-methano-2H-1-benzopyran-2-ol [PDF]

, 1985
Eine Synthese für das Lactol 1 wird beschrieben und seine Eignung als Reagens zur Racemattrennung an einigen Beispielen gezeigt. Aufgrund einer Röntgenstruktur und konformationsanalytischer Überlegungen wird eine allgemeine Regel erarbeitet, nach welcher
Bourne, Dankova, Davies, Haller, Holmberg, Lemieux, Lemieux, Main, Martin, Noe, Noe, Noe, Pickard, Pickard, Rupe, Sheldrick, Weidmann   +16 more
core   +1 more source

5,7-Dihydroxy-6,4′-dimethoxyflavone

Acta Crystallographica Section E, 2008
In the title compound, C17H14O6, the benzopyran ring system is essentially planar and forms a dihedral angle of 6.84 (4)° with the other benzene ring. In the crystal structure, centrosymmetrically related molecules are linked into dimers by O&#
Ming-Yue Mou, Ke Pi, Qi-Long Zhang, Yun-Qian Zhang, Qian-Jun Zhang   +4 more
doaj   +1 more source

Synthesis and anti-norovirus activity of pyranobenzopyrone compounds [PDF]

, 2012
During the last decade, noroviruses have gained media attention as the cause of large scale outbreaks of gastroenteritis on cruise ships, dormitories, nursing homes, etc.
Chang, Kyeong-Ok, Hua, Duy H., Kim, Yunjeong, Lu, Jianyu, Nguyen, Thi D.T., Pokhrel, Laxman, Prior, Allan M.   +6 more
core   +1 more source

Synthesis and Biological Evaluation of Some New Coumarin Derivatives

Molecules, 2003
Pyrimidino[5`,4`-6,5]-,pyridino[3`,2`-6,5]- and pyrrolo[3`,2`-5,6]4H-pyrano-[3,2-c][1]benzopyran-6-one derivatives (5-7 and 10) could be obtained via reaction of 2-amino-4-(p-bromophenyl)-3-cyano(carboethoxy)-4H,5H-pyrano[3,2-c][1]benzopyran-5-ones (3a,b)
M. Y. El-Kady, M. S. Mostafa, M. A. Al-Haiza   +2 more
doaj   +1 more source