Effects of thiazides and new findings on kidney stones and dysglycemic side effects
Acta Physiologica, Volume 240, Issue 7, July 2024.Abstract Thiazide and thiazide‐like diuretics (thiazides) belong to the most frequently prescribed drugs worldwide. By virtue of their natriuretic and vasodilating properties, thiazides effectively lower blood pressure and prevent adverse cardiovascular outcomes.
Matteo Bargagli +2 more
wiley +1 more source
HCV antiviral resistance: The impact of in vitro studies on the development of antiviral agents targeting the viral NS5B polymerase [PDF]
, 2005 The high prevalence of the disease caused by hepatitis C virus (HCV) and the limited efficacy of interferon-based therapies have stimulated the search for safer and more effective drugs.
G. Migliaccio +4 more
core +1 more source
From Conventional to Sustainable Catalytic Approaches for Heterocycles Synthesis
ChemSusChem, Volume 17, Issue 8, April 22, 2024.Catalysed synthetic methods, such as transition metals, organocatalysts, photocatalysts, iodine‐catalysed reaction, electrochemical reactions and green innovative methods are of great interest for the sustainable synthesis of heterocyclic compounds, important building blocks for several applications.
Carla Rizzo +4 more
wiley +1 more source
The Pharmacology of Newer Diuretics [PDF]
, 1967 There are now a number of different classes of diuretics with different pharmacologic effects. Several considerations dictate the choice of diuretic: 1. The responsiveness of the patient is of prime importance. If the patient is not known to be resistant
Wasserman, Albert J.
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Physiological Reports, Volume 12, Issue 8, April 2024.Abstract High sodium intake is decisive in the incidence increase and prevalence of hypertension, which has an impact on skeletal muscle functionality. Diazoxide is an antihypertensive agent that inhibits insulin secretion and is an opener of KATP channels (adosine triphosphate sensitive potasium channels).
Estefanía Bravo Sánchez +7 more
wiley +1 more source
Palladium‐Catalyzed Domino Reaction for the Synthesis of 3‐Amino 1,2,4‐Benzothiadiazine 1,1‐Dioxides
Advanced Synthesis &Catalysis, Volume 366, Issue 4, Page 717-724, February 20, 2024.Abstract A palladium‐catalyzed domino reaction of 2‐azidosulfonamides and isocyanides enables the synthesis of 3‐amino‐substituted 1,2,4‐benzothiadiazine 1,1‐dioxides at room temperature. By applying commercially available Pd(dba)2 in catalyst loadings as low as 1.0 mol%, a variety of 21 differently substituted 2H‐1,2,4‐benzothiadiazine 1,1‐dioxides ...
Renè Hommelsheim +5 more
wiley +1 more source
Új szintézismódszerek kidolgozása és alkalmazása célzott hatásterületen aktív heterociklusos molekulák szintézisére = Elaboration and application of new synthetic methodologies for the synthesis of heterocyclic molecules of aimed biological activity [PDF]
, 2013 Pályázati kutatásunk alapvető célja az volt, hogy néhány, a legutóbbi időkben felismert új szintézis-lehetőséget laboratóriumunkban meghonosítsunk, saját magunk új módszereket dolgozzunk ki, és mindezek segítségével felfedező kutatásokat végezzünk ...
Gömöry, Ágnes +15 more
core
Observations on a new benzothiadiazine diuretic - trichlormethiazide [PDF]
, 2018 No ...
Boardman, R. +4 more
core +1 more source
A Comprehensive Photochemical and Photophysical Assay Exploring the Photoreactivity of Drugs [PDF]
, 1988 What are the interests of a pharmaceutical company in «Photochemistry of Drugs» ? First of all drug-safety: safety by avoiding adverse effects in humans caused by exposure to light after the administration of certain drugs.
Oppenländer, Thomas
core +2 more sources