Heteroarylalkanoic acids with possible antiinflammatory activities, III
, 1985 The Ms deals with the synthesis and in vivo testing of a series of benzothiadiazines as antiinflammatory ...
PARENTI, Carlo +3 more
core +1 more source
Effects of thiazides and new findings on kidney stones and dysglycemic side effects
Acta Physiologica, Volume 240, Issue 7, July 2024.Abstract Thiazide and thiazide‐like diuretics (thiazides) belong to the most frequently prescribed drugs worldwide. By virtue of their natriuretic and vasodilating properties, thiazides effectively lower blood pressure and prevent adverse cardiovascular outcomes.
Matteo Bargagli +2 more
wiley +1 more source
From Conventional to Sustainable Catalytic Approaches for Heterocycles Synthesis
ChemSusChem, Volume 17, Issue 8, April 22, 2024.Catalysed synthetic methods, such as transition metals, organocatalysts, photocatalysts, iodine‐catalysed reaction, electrochemical reactions and green innovative methods are of great interest for the sustainable synthesis of heterocyclic compounds, important building blocks for several applications.
Carla Rizzo +4 more
wiley +1 more source
Regioselective cyclization of chloroacylaminobenzenesulfonamide derivatives
, 2012 Chloroacylaminobenzensulfonamides regioselectively thermally cyclize under solvent free conditions to 1,2,4-benzothiadiazines with five- and six-membered rings fused on face ...
PARENTI, Carlo +10 more
core +1 more source
Physiological Reports, Volume 12, Issue 8, April 2024.Abstract High sodium intake is decisive in the incidence increase and prevalence of hypertension, which has an impact on skeletal muscle functionality. Diazoxide is an antihypertensive agent that inhibits insulin secretion and is an opener of KATP channels (adosine triphosphate sensitive potasium channels).
Estefanía Bravo Sánchez +7 more
wiley +1 more source
Palladium‐Catalyzed Domino Reaction for the Synthesis of 3‐Amino 1,2,4‐Benzothiadiazine 1,1‐Dioxides
Advanced Synthesis &Catalysis, Volume 366, Issue 4, Page 717-724, February 20, 2024.Abstract A palladium‐catalyzed domino reaction of 2‐azidosulfonamides and isocyanides enables the synthesis of 3‐amino‐substituted 1,2,4‐benzothiadiazine 1,1‐dioxides at room temperature. By applying commercially available Pd(dba)2 in catalyst loadings as low as 1.0 mol%, a variety of 21 differently substituted 2H‐1,2,4‐benzothiadiazine 1,1‐dioxides ...
Renè Hommelsheim +5 more
wiley +1 more source
New derivatives of 1,2,4-benzothiadiazines and their coordination chemistry [PDF]
, 2018 Chapter 1 provides an introduction to coordination chemistry and polydentate N-donor ligands along with a synopsis of heterocycles with N and S/N donor atoms.
Pringouri, Konstantina
core +1 more source
Structures of SUR2 NBD1 / Drug Complexes Determined with NMR Spectroscopy and Data Driven Docking [PDF]
, 2021 ATP-sensitive potassium (KATP) channels are formed by four inward-rectifying K+ channels and four regulatory sulfonylurea receptors (SURs). ATP binding and hydrolysis at the SUR nucleotide binding domains (NBDs) regulates opening of the KATP channel pore.
Sayewich, Jonathan Scott
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QSAR and Docking Studies on 1,1-Dioxo-2H-benzothiadiazines Acting as HCV NS5B Polymerase Inhibitors
, 2015 Quantitative structure-activity relationship (QSAR) and molecular modeling studies have been made on a large series of 1,1-dioxo-2H-benzothiadiazines acting as HCV NS5B polymerase inhibitors. A multiple linear regression analysis has pointed out that the
Agrawal, Vijay; APS University +5 more
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Ligand Synthesis for Hepatitis C Virus Internal Ribosome Entry Site [PDF]
, 2017 Benzothiadiazines were synthesized and tested for their binding affinity with hepatitis C virus internal ribosome entry site subdomain IIa using FRET assay.
Wang, Zihao
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