Results 31 to 40 of about 547 (150)

Regioselective cyclization of chloroacylaminobenzenesulfonamide derivatives

, 2012
Chloroacylaminobenzensulfonamides regioselectively thermally cyclize under solvent free conditions to 1,2,4-benzothiadiazines with five- and six-membered rings fused on face ...
PARENTI, Carlo, C. PARENTI, G. CANNAZZA, BATTISTI, UMBERTO MARIA, C. Citti, M. M. CARROZZO, TROISI, Luigino, CANNAZZA, Giuseppe, CARROZZO, Marina Maria, L. Troisi, U. M. BATTISTI   +10 more
core   +1 more source

Diazoxide and moderate‐intensity exercise improve skeletal muscle function by decreasing oxidants and enhancing antioxidant defenses in hypertensive male rats

Physiological Reports, Volume 12, Issue 8, April 2024.
Abstract High sodium intake is decisive in the incidence increase and prevalence of hypertension, which has an impact on skeletal muscle functionality. Diazoxide is an antihypertensive agent that inhibits insulin secretion and is an opener of KATP channels (adosine triphosphate sensitive potasium channels).
Estefanía Bravo Sánchez, César J. Nolasco Ruíz, Mariana Gómez‐Barroso, Christian Cortés Rojo, Alain R. Rodríguez Orozco, Alfredo Saavedra Molina, Salvador Manzo Ávalos, Rocío Montoya Pérez   +7 more
wiley   +1 more source

Palladium‐Catalyzed Domino Reaction for the Synthesis of 3‐Amino 1,2,4‐Benzothiadiazine 1,1‐Dioxides

Advanced Synthesis &Catalysis, Volume 366, Issue 4, Page 717-724, February 20, 2024.
Abstract A palladium‐catalyzed domino reaction of 2‐azidosulfonamides and isocyanides enables the synthesis of 3‐amino‐substituted 1,2,4‐benzothiadiazine 1,1‐dioxides at room temperature. By applying commercially available Pd(dba)2 in catalyst loadings as low as 1.0 mol%, a variety of 21 differently substituted 2H‐1,2,4‐benzothiadiazine 1,1‐dioxides ...
Renè Hommelsheim, Robin van Nahl, Lena M. Hanek, Jas S. Ward, Kari Rissanen, Carsten Bolm   +5 more
wiley   +1 more source

Intramolecular Azide to Alkene Cycloadditions for the Construction of Pyrrolobenzodiazepines and Azetidino-Benzodiazepines

, 2014
The coupling of proline- and azetidinone-substituted alkenes to 2-azidobenzoic and 2-azidobenzenesulfonic acid gives precursors that undergo intramolecular azide to alkene 1,3-dipolar cycloadditions to give imine-, triazoline- or aziridine-containing ...
O'Gorman, Paul A, Chambers, Christopher Steven, Christopher Chambers, Jamshaid, Faisal, Paul O'Gorman, Karl Hemming, Faisal Jamshaid, Hemming, Karl, Chambers, Christopher S, Christopher S. Chambers, Paul A. O'Gorman, Paul O\u27Gorman   +11 more
core   +1 more source

Synthesis and properties of some 4H-1, 3, 4 benzothiadiazines /|nby Darko J. Vukov. -- 260 St. Catharines, Ont. : [s. n.],

, 1972
The work herein has been divided into five sections. In the first section, a new method of converting N-aroyl- hydrazines to hydrazidic halides is described.
Vukov, Darko J.
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QSAR and Docking Studies on 1,1-Dioxo-2H-benzothiadiazines Acting as HCV NS5B Polymerase Inhibitors

, 2015
Quantitative structure-activity relationship (QSAR) and molecular modeling studies have been made on a large series of 1,1-dioxo-2H-benzothiadiazines acting as HCV NS5B polymerase inhibitors. A multiple linear regression analysis has pointed out that the
Agrawal, Vijay; APS University, Guptac, Satya; National Institute of Technical Teachers’ Training and Research, Shaik, Basheerulla; National Institute of Technical Teachers’ Training and Research, Singh, Neelu; Sagar Institute of Research Technology-Excellence, Anithaa, K.; Career College, Ahmad, Izhar; National Institute of Technical Teachers’ Training and Research   +5 more
core  

Ligand Synthesis for Hepatitis C Virus Internal Ribosome Entry Site [PDF]

, 2017
Benzothiadiazines were synthesized and tested for their binding affinity with hepatitis C virus internal ribosome entry site subdomain IIa using FRET assay.
Wang, Zihao
core  

Anti-HIV-1 Activity of Benzothiadiazine Dioxide

Antiviral Chemistry and Chemotherapy, 2001
Antiviral assays carried out on the potent benzothiadiazine dioxide (BTD) human cytomegalovirus (HCMV) inhibitors have led us to find marginal but selective anti-HIV-1 activity. Specific pharmacological studies, such as time of addition experiments and assays on specific viral strains with mutations on its reverse transcriptase, have indicated that ...
Martinez, A., Gil, C., Castro, A., Perez, C., Witvrouw, Myriam, Pannecouque, Christophe, Balzarini, Jan, De Clercq, Erik   +7 more
openaire   +4 more sources

Simultaneous Determination of Enantiomerizationand Hydrolysis Kinetic Parameters of ChiralN-Alkylbenzothiadiazine Derivatives

, 2010
On-column stopped flow multidimensional HPLC (sfMDHPLC) anddynamic high-performance liquid chromatography were applied to investigate the influenceof alkyl substituents at the sulfonamidic and amino moieties of benzothiadiazine1,1-dioxide derivatives on ...
PARENTI, Carlo, BATTISTI, UMBERTO MARIA, BRAGHIROLI, Daniela, CANNAZZA, Giuseppe, CARROZZO, Marina Maria   +4 more
core   +1 more source

Heteroarylalkanoic acids with possible antiinflammatory activities Part 6

, 1989
The Ms deals with the synthesis and in vivo testing of a series of benzothiadiazines as antiinflammatory ...
PARENTI, Carlo, Di Bella M, Rossi T., Raffa L, Gamberini G, COSTANTINO, Luca   +5 more
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