Results 11 to 20 of about 1,143 (191)
Evaluation of 1,2-Benzothiazine 1,1-Dioxide Derivatives In Vitro Activity towards Clinical-Relevant Microorganisms and Fibroblasts [PDF]
Molecules, 2020 The global concern related with growing number of bacterial pathogens, resistant to numerous antibiotics, prone scientific environment to search for new antimicrobials.
Ruth K. Dudek-Wicher +5 more
doaj +2 more sources
Sulfonic Acid Functionalized Nano-γ-Al2O3: A New, Efficient, and Reusable Catalyst for Synthesis of 3-Substituted-2H-1,4-Benzothiazines [PDF]
The Scientific World Journal, 2013 A simple and efficient synthetic protocol has been developed for the synthesis of 3-substituted-2H-1,4-benzothiazines by using a novel sulfonic acid functionalized nano-γ-Al2O3 catalyst, devoid of corrosive acidic, and basic reagents.
Wei Lin Li, Shuan Bao Tian, Feng Zhu
doaj +2 more sources
An Ugi-Joullié Platform for Medicinally Relevant 1,4-Dihydrobenzothiazines. [PDF]
ChemMedChemA series of benzothiazine derivatives was efficiently synthesized via an UJ‐2CR of a preformed imine and diverse isocyanides. The method features mild, room‐temperature conditions, broad functional‐group tolerance, and scalability, enabling rapid access to a chemically diverse library of 19 adducts with potential for further medicinal chemistry ...
Lei X +9 more
europepmc +2 more sources
ARKIVOC, 2011 The synthesis of 4-alkoxy-1H-2,1-benzothiazine 2,2-dioxide derivatives was achieved through an unexpected base-mediated cyclization of N-benzoyl-N-methylsulfonylanthranilates.
Giuseppe Manfroni +4 more
doaj +2 more sources
Reagent-Controlled Divergent Synthesis of 2‑Amino-1,3-Benzoxazines and 2‑Amino-1,3-Benzothiazines
, 2019 A reagent-controlled chemoselective process has been devised for the synthesis of 4H-1,3-benzoxazines and related biologically important heterocycles in high yields under mild conditions.
V. P. Rama Kishore Putta (8194965) +7 more
core +5 more sources
Química Nova, 2006 The synthesis and physico-chemical properties of new 6-acetylamino or 6-benzoyl-amino 2-benzylidene-4-methyl-4H-benzo[1,4]thiazin-3-ones and 6-benzoylamino or 6-nitro 2-benzylidene-4H-benzo[1,4]thiazin-3-ones are described.
Ana Maria Alves de Souza +6 more
doaj +3 more sources
SPECTRAL EVALUATION AND ANTIMICROBIAL ACTIVITY OF SYNTHESIZED 4H-1,4-BENZOTHIAZINES [PDF]
, 2021 Objective: 4H-1,4-Benzothiazines constitute an important class of heterocycles containing 1,4-thiazine ring fused to benzene ring. They are extensively used as tranquilizer, antispasmodic, central nervous system depressant, antiulcer, antibacterial ...
GOYAL, ARUN
core +1 more source
, 2021 A facile access to highly fused tetracyclic indeno-1,2-benzothiazines has been established via a Rh(III)-catalyzed C–H bond activation and intramolecular annulation cascade between sulfoximides and all-carbon diazo indandiones.
Hong Liu +19 more
core +1 more source
(R)-(−)-2-[(5-Oxido-5-phenyl-5λ4-isoquino[4,3-c][2,1]benzothiazin-12-yl)amino]benzonitrile
Molbank, 2014 Copper-catalyzed cross-coupling between (S)-S-methyl-S-phenylsulfoximine (1) and 2-iodobenzonitrile (2) resulted in the discovery of an unprecedented one-pot triple arylation sequence to give (R)-(−)-2-[(5-oxido-5-phenyl-5λ4-isoquino[4,3-c][2,1 ...
Marcus Frings +2 more
doaj +1 more source
Synthesis of quinazolino‐1,3‐benzothiazine derivatives [PDF]
Journal of Heterocyclic Chemistry, 1992 AbstractThe ring‐closure reactions of N‐(3,4‐dimethoxyphenylthiomethyl)‐2‐nitrobenzamide derivatives 5a,b with phosphoryl chloride gave 4‐(2‐nitrophenyl)‐2H1,3‐benzothiazine derivatives 7a,b, which on reduction yielded 4‐(2′‐aminophenyl)‐3,4‐dihydro‐2H‐1,3‐benzothiazines 8a,b.
Szabó János +5 more
openaire +2 more sources