Results 31 to 40 of about 2,731 (212)

Prenatal Cocaine Exposure and Infantile Psychomotor Outcome

Pediatric Neurology Briefs, 2002
The effects of prenatal cocaine exposure on child development outcomes were studied prospectively in an obstetric unit of a large US urban teaching hospital at Case Western Reserve University, Cleveland, OH.
J Gordon Millichap
doaj   +1 more source

Cocaine and benzoylecgonine in saliva, serum, and urine

Clinical Chemistry, 1993
Abstract We studied the feasibility of using saliva to detect cocaine and benzoylecgonine. Saliva was collected as an ultrafiltrate directly in the mouth with an osmotic device. We analyzed by immunoassay matched samples of urine, blood, and salivary ultrafiltrate from 69 patients who had used cocaine within 24 h of sample collection ...
W, Schramm, P A, Craig, R H, Smith, G E, Berger   +3 more
openaire   +2 more sources

Economical Synthesis of 13C-Labeled Opiates, Cocaine Derivatives and Selected Urinary Metabolites by Derivatization of the Natural Products

Molecules, 2015
The illegal use of opiates and cocaine is a challenge world-wide, but some derivatives are also valuable pharmaceuticals. Reference samples of the active ingredients and their metabolites are needed both for controlling administration in the clinic and ...
Morten Karlsen, Huiling Liu, Jon Eigill Johansen, Bård Helge Hoff   +3 more
doaj   +1 more source

Probing cocaine-antibody interactions in buffer and human serum. [PDF]

PLoS ONE, 2012
Despite progress in cocaine immunotherapy, the kinetic and thermodynamic properties of antibodies which bind to cocaine and its metabolites are not well understood. It is also not clear how the interactions between them differ in a complex matrix such as
Muthu Ramakrishnan, Fernando Alves De Melo, Berma M Kinsey, John E Ladbury, Thomas R Kosten, Frank M Orson   +5 more
doaj   +1 more source

Optimization of Parallel Artificial Liquid Membrane Extraction for the Determination of Over 50 Psychoactive Substances in Oral Fluid Through UHPLC-MS/MS. [PDF]

Drug Test Anal
This study is related to the development of a microextraction method for the determination of 56 psychoactive substances in oral fluid. Sample clean‐up is obtained by parallel artificial liquid membrane extraction and analyzed by liquid chromatography–tandem mass spectrometry.
Croce M, Montesano C, Bracaglia I, Bartolini F, Mascini M, Compagnone D, Sergi M.   +6 more
europepmc   +2 more sources

Hair analysis following chronic smoked-drugs-of-abuse exposure in adults and their toddler: a case report

Journal of Medical Case Reports, 2011
Introduction Over the past two decades, the study of chronic cocaine and crack cocaine exposure in the pediatric population has been focused on the potential adverse effects, especially in the prenatal period and early childhood.
Papaseit Esther, Joya Xavier, Velasco Marta, Civit Ester, Mota Pau, Bertran Marta, Vall Oriol, Garcia-Algar Oscar   +7 more
doaj   +1 more source

Cocaine: An Updated Overview on Chemistry, Detection, Biokinetics, and Pharmacotoxicological Aspects including Abuse Pattern

Toxins, 2022
Cocaine is one of the most consumed stimulants throughout the world, as official sources report. It is a naturally occurring sympathomimetic tropane alkaloid derived from the leaves of Erythroxylon coca, which has been used by South American locals for ...
Rita Roque Bravo, Ana Carolina Faria, Andreia Machado Brito-da-Costa, Helena Carmo, Přemysl Mladěnka, Diana Dias da Silva, Fernando Remião, on behalf of The OEMONOM Researchers   +7 more
doaj   +1 more source

Effects of cocaine, benzoylecgonine, and cocaine metabolites in cannulated pressurized fetal sheep cerebral arteries

, 1994
Prenatal cocaine exposure has been reported to cause neurovascular complications in the developing fetus. To determine the effect of cocaine on the fetal neurovasculature, we studied the in vitro response of fetal sheep cerebral arteries to cocaine and ...
L. J. Torgerson, R. F. Covert, J. A. Madden, M. D. Schreiber   +3 more
core   +1 more source

Silent Cocaine Poisoning [PDF]

Asia Pacific Journal of Medical Toxicology, 2014
Background: Cocaine poisoning is known for causing severe clinical effects such as tachycardia, hypertension, agitation and confusion. Absence of clinical manifestations in cocaine poisoning is unusual.
Rachid El-Jaoudi, Luc Humbert, Frederique Grisel, Yahya Cherrah, Daniel Mathieu, Michelle Lhermitte   +5 more
doaj  

m-Hydroxybenzoylecgonine: an important contributor to the immunoreactivity in assays for benzoylecgonine in meconium

, 1993
Meconium has been reported to be a more suitable specimen than maternal or neonatal urine for detecting fetal exposure to cocaine. In a study comparing various immunoassays with gas chromatography/mass spectrometry (GC/MS), several unexplained ...
Hime, G W, Wu, N C, Hearn, W L, Steele, B W, Bandstra, E S   +4 more
core   +1 more source