Results 21 to 30 of about 2,731 (212)
Green Analytical Chemistry, 2023 The purpose of the research was to develop a new method that would allow the determination of selected drugs (mephedrone, MDMA, and cocaine and its metabolites: benzoylecgonine, norcocaine, and cocaethylene) in whole blood, while meeting not only the ...
Alicja Chromiec +2 more
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Presence of Parent Cocaine in the Absence of Benzoylecgonine in Urine† [PDF]
Journal of Analytical Toxicology, 2018 Cocaine (COC) is widely abused and associated with significant adverse effects. Forensic and clinical laboratories often test for COC intake through detection of the primary metabolite, benzoylecgonine (BZE) in urine. Testing for BZE alone may result in false-negative determinations in situations where COC is recently administered or metabolism is ...
Brandi L, Puet +4 more
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Biochemistry and Biophysics Reports, 2022 We analyzed the thermodynamics of binding of cocaine and several cocaine metabolites to a humanized anti-cocaine mAb (h2E2), which is under development for the treatment of cocaine use disorders, using isothermal titration calorimetry.
Terence L. Kirley, Andrew B. Norman
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Scientific Reports, 2023 The global drug market has been significantly impacted by the emergence of new psychoactive substances, leading to challenges in creating effective legislative controls and their use within recreational drug consumption.
Bethan Davies +2 more
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Preventive Medicine Reports, 2021 The primary objective of the present study was to evaluate the frequency of positive tests for alcohol and drugs during roadside testing or after road accidents among drivers in the Brittany region of France.
Brendan Le Daré +6 more
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Cocaine Exposure in Childhood: Neurologic Signs
Pediatric Neurology Briefs, 1994 Neurologic manifestations of cocaine exposure in 19 (46%) of 41 children, ages 2 months to 18 years, found to have cocaine-positive urine screening tests during a 1-year period (Jan - Dec 1990), are reported from the Children’s National Medical Center ...
J Gordon Millichap
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Determination of cocaine and its metabolites in blood by gas chromatography coupled with mass spectrometry (GC-MS). [PDF]
Batna Journal of Medical SciencesIntroduction. This article aims to present a simple and sensitive chromatographic method, carried out in the gas phase using detection by mass spectrometry to identify and quantify cocaine and its metabolites in the blood, notably Benzoylecgonine and ...
Soumia DALEM +3 more
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Presence of illicit drugs and pharmaceutical residues in the wastewaters of an eastern Canadian city
Journal of Xenobiotics, 2016 Not ...
A. Palardy, J.-P. Gagné, L. Tremblay
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Anti-Cocaine IgA Rather Than IgG Mediates Vaccine Protection from Cocaine Use
Pharmaceutics, 2022 In developing a vaccine for fentanyl use disorder, we observed that IgA was the best correlate of vaccine-mediated protection from injected drug challenge, rather than IgG or binding affinity. Recent evidence shows that IgA secreting cells line the blood–
Thomas R. Kosten +3 more
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Positivity to Cocaine and/or Benzoylecgonine in Confirmation Analyses for On-Road Tests in Spain [PDF]
International Journal of Environmental Research and Public Health, 2021 We are using real-life data in order to determine the prevalence of driving with the presence of cocaine and/or benzoylecgonine (BZE), their concentrations, and their use in combination with other drugs. This study assessed data on Spanish drivers with confirmed drug-positive results recorded by the Spanish National Traffic Agency from 2011–2016 ...
Herrera Gómez, Francisco Magno +3 more
openaire +2 more sources