Tumor Diagnosis and Treatment Based on Stimuli‐Responsive Aggregation of Gold Nanoparticles
This review summarizes the current strategies for inducing gold nanoparticles aggregation and its advances in tumor diagnosis and treatment. The authors hope this review can provide a valuable reference for the further development of AuNPs clinical applications.
Xiaowei Chang, Huaiyu Wang, Xin Chen
wiley +1 more source
Quilamine HQ1-44, an iron chelator vectorized toward tumor cells by the polyamine transport system, inhibits HCT116 tumor growth without adverse effect [PDF]
International audienceTumor cell growth requires large iron quantities and the deprivation of this metal induced by synthetic metal chelators is therefore an attractive method for limiting the cancer cell proliferation.
Cannie, Isabelle +7 more
core +3 more sources
Metalloantibiotics: A library of piano‐stool and polypyridyl Ru(II) complexes bearing thiazolhidrazinylidene‐chroman‐2,4‐diones was evaluated as metalloantibiotics. A complex is identified with a noteworthy minimum inhibitor concentration value of 3.1 μm and no toxicity in healthy eukaryotic cells.
Fatlinda Rahmani +4 more
wiley +1 more source
Recent advancements in the preparation of immobilized enzymes have improved both batch and continuous flow biocatalytic processes, essential for cost‐effective, sustainable production in the fine chemicals and pharmaceutical industries. This review examines advancements in carrier‐free methods, entrapment strategies, and support‐based approaches ...
Stefania Patti +5 more
wiley +1 more source
This Personal Account discusses our recent work on metal‐ and organo‐catalyzed aerobic oxidation protocols, highlighting key breakthroughs in amine oxidation, heterocycle synthesis, and the versatile use of ortho‐naphthoquinone catalysts in dehydrogenation and deamination.
Rahulkumar Patel +3 more
wiley +1 more source
A Catalytic Mechanism for Benzylamine Oxidase from Pig Plasma [PDF]
Ammonium ion is shown to decrease the rate constants for Schiff's base formation and formation of a reduced intermediate during the catalytic cycle of benzylamine oxidase from pig plasma. The rate constant for reoxidation of the reduced intermediate is also inhibited whilst the rate constant for conversion of the oxidised enzyme form back to native ...
K D, Yadav, P F, Knowles
openaire +2 more sources
Development of novel fluorine-18 labeled PET radioligands for monoamine oxidase B (MAO-B) [PDF]
Monoamine oxidases (MAO-A and MAO-B) are important enzymes regulating the levels of monoaminergic neurotransmitters. Selectiv e and irreversible MAO-B inhibitors such as L -deprenyl and rasagiline are clinically used for the t reatment of ...
Nag, Sangram
core +2 more sources
Opipramol inhibits lipolysis in human adipocytes without altering glucose uptake and differently from antipsychotic and antidepressant drugs with adverse effects on body weight control [PDF]
Treatment with several antipsychotic drugs exhibits a tendency to induce weight gain and diabetic complications. The proposed mechanisms by which the atypical antipsychotic drug olanzapine increases body weight include central dysregulations leading to ...
Boulet, N. +8 more
core +2 more sources
Recent advances in non‐noble metal‐based electrocatalysts for hybrid water electrolysis systems
This review presents an introduction on coupling electrochemical oxidation of small molecules to replace the oxygen evolution reaction at the anode and the hydrogen evolution reaction at the cathode in an electrolyzer, which would simultaneously for the generation of high‐value chemicals or pollutant degradation and highly efficient production of ...
Xiaoyu Zhang +7 more
wiley +1 more source
Semicarbazide-sensitive amine oxidase (SSAO): from cell to circulation [PDF]
Semicarbazide-sensitive amine oxidase (SSAO) is a multi-functional enzyme widely present in nature. It converts primary amines into their corresponding aldehydes, while generating H(2)O(2) and NH(3).
Bagghoe, U. +3 more
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