Berberis microphylla: A species with phenotypic plasticity in different climatic conditions [PDF]
Berberis microphylla G. Forst., commonly called as "calafate" produces small fruits with high content of carbohydrates, phenols and antioxidants. The objective of this work was to characterize the vegetative and reproductive cycle of Berberis microphylla
Alonso, Marta +2 more
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A preliminary study on the synthetic lethal effect of berberine and olaparib on pancreatic cancer cells and its mechanism [PDF]
Pancreatic cancer is a kind of malignant tumor with high mortality rate. Early operation and late chemoradiotherapy are the treatment criteria, but the prognosis is still poor.
Zhang Chengyong +9 more
doaj +1 more source
Comparison of chemical profiles and effectiveness between Erxian decoction and mixtures of decoctions of its individual herbs : a novel approach for identification of the standard chemicals [PDF]
Acknowledgements This study was partially supported by grants from the Seed Funding Programme for Basic Research (Project Number 201211159146 and 201411159213), the University of Hong Kong.
Cheung, H. P. +8 more
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Genome-Wide Transposon Screen of a Pseudomonas syringae mexB Mutant Reveals the Substrates of Efflux Transporters. [PDF]
Bacteria express numerous efflux transporters that confer resistance to diverse toxicants present in their environment. Due to a high level of functional redundancy of these transporters, it is difficult to identify those that are of most importance in ...
Deutschbauer, Adam M +4 more
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Effect of a novel nutraceutical combination on serum lipoprotein functional profile and circulating PCSK9 [PDF]
BACKGROUND: A beneficial effect on cardiovascular risk may be obtained by improving lipid-related serum lipoprotein functions such as high-density lipoproteins (HDLs) cholesterol efflux capacity (CEC) and serum cholesterol loading capacity (CLC) and by ...
Adorni, Maria Pia +7 more
core +3 more sources
Uncoupling protein 2: a key player and a potential therapeutic target in vascular diseases [PDF]
Uncoupling protein 2 (UCP2) is an inner mitochondrial membrane protein that belongs to the uncoupling protein family and plays an important role in lowering mitochondrial membrane potential and dissipating metabolic energy with prevention of oxidative ...
Forte, Maurizio +6 more
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Protective effects of berberine on intestinal ischemia and reperfusion injury in rats [PDF]
This study aims to investigate the potential protective effects of berberine on ischemia and reperfusion (IR) injury in rats. Thirty male rats were randomly divided into three experimental groups as follows: the sham group, the IR group and the ...
Chen Tanzhou, Lv Bin
doaj +1 more source
The anti-sepsis activity of the components of Huanglian Jiedu Decoction with high lipid A-binding affinity [PDF]
Huanglian Jiedu Decoction (HJD), one of the classic recipes for relieving toxicity and fever, is a common method for treating sepsis in China. However, the effective components of HJD have not yet been identified.
Chen, Guirong +7 more
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Involvement of the leaf-specific multidrug and toxic compound extrusion (MATE) transporter Nt-JAT2 in vacuolar sequestration of nicotine in Nicotiana tabacum [PDF]
Alkaloids play a key role in higher plant defense against pathogens and herbivores. Following its biosynthesis in root tissues, nicotine, the major alkaloid of Nicotiana species, is translocated via xylem transport toward the accumulation sites, leaf ...
Goossens, Alain +11 more
core +8 more sources
Molecular and Crystal Structures of Three Berberine Derivatives
Berberine azide, berberine thiocyanate, and 8-cyano-8H-berberine were prepared from berberine chloride, a quaternary protoberberine alkaloid. The molecular and crystal structures of all compounds are reported and discussed.
JiřàDostál +4 more
doaj +1 more source

