Results 31 to 40 of about 28,872 (258)

A preliminary study on the synthetic lethal effect of berberine and olaparib on pancreatic cancer cells and its mechanism [PDF]

E3S Web of Conferences, 2021
Pancreatic cancer is a kind of malignant tumor with high mortality rate. Early operation and late chemoradiotherapy are the treatment criteria, but the prognosis is still poor.
Zhang Chengyong, Yang Tingting, Chen Xiaoting, Xu Jiexuan, Liang Danlu, Yi Huairu, Chen Size, Huang Lanlan, Liu Naihua, Lin Shaoqiang   +9 more
doaj   +1 more source

Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: The cellular mechanism [PDF]

, 2010
Extensive studies have revealed that berberine, a small molecule derived from Coptidis rhizoma (Huanglian in Chinese) and many other plants, has strong anti-tumor properties. To better understand berberine-induced cell death and its underlying mechanisms
Meifen Zhu, Tong, Y, Tsao, SW, Feng, Y, Sai-Wah Tsao, Zhu, M, Kwan Man, Man, K, Tsang, CM, Yao Tong, Yibin Feng, Wang, N, Chi-Man Tsang, Ning Wang   +13 more
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Alternative final steps in berberine biosynthesis in Coptis japonica cell cultures [PDF]

, 1988
In Coptis japonica cell cultures an alternative pathway has been discovered which leads from (S)-tetrahydrocolumbamine via (S)-canadine to berberine. The two enzymes involved have been partially purified.
Wanner, G., Rüffer, Martina, Tabata, M., Zenk, Meinhart H., Galneder, E.   +4 more
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Protective effects of berberine on intestinal ischemia and reperfusion injury in rats [PDF]

Archives of Biological Sciences, 2017
This study aims to investigate the potential protective effects of berberine on ischemia and reperfusion (IR) injury in rats. Thirty male rats were randomly divided into three experimental groups as follows: the sham group, the IR group and the ...
Chen Tanzhou, Lv Bin
doaj   +1 more source

Berberine Inhibits the Release of Glutamate in Nerve Terminals from Rat Cerebral Cortex. [PDF]

PLoS ONE, 2013
Berberine, an isoquinoline plant alkaloid, protects neurons against neurotoxicity. An excessive release of glutamate is considered to be one of the molecular mechanisms of neuronal damage in several neurological diseases.
Tzu-Yu Lin, Yu-Wan Lin, Cheng-Wei Lu, Shu-Kuei Huang, Su-Jane Wang   +4 more
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Berberine: A Promising Treatment for Neurodegenerative Diseases

Frontiers in Pharmacology, 2022
Berberine, as a natural alkaloid compound, is characterized by a diversity of pharmacological effects. In recent years, many researches focused on the role of berberine in central nervous system diseases.
Ziqian Cheng, Chenglan Kang, Songtian Che, Jingyun Su, Qihan Sun, Tongtong Ge, Yi Guo, Jiayin Lv, Zhihui Sun, Wei Yang, Bingjin Li, Xin Li, Ranji Cui   +12 more
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Berberine: metabolic and cardiovascular effects in preclinical and clinical trials [PDF]

, 2009
Arrigo FG Cicero1, Sibel Ertek21Internal Medicine, Aging and Kidney Diseases Department, Sant’Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy; 2Ufuk University, Medical Faculty, Dr Ridvan Ege Hospital, Department of ...
CICERO, ARRIGO FRANCESCO GIUSEPPE, Ertek S., Arrigo FG Cicero, Cicero, Arrigo F. G., Sibel Ertek, Ertek, Sibel   +5 more
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Preparation of Berberine@carbon Dots Nano-Formulation: Synthesis, Characterization and Herbicidal Activity against Echinochloa crus-galli and Amaranthus retroflexus Two Common Species of Weed

Nanomaterials, 2022
Berberine (Ber) is easy to synthesize and has a variety of biological and pharmacological activities. At present, the existing studies on berberine have focused predominantly on its antibacterial activity; its herbicidal activity is rarely reported.
Junhu Xu, Shuang Rong, Ziqi Qin, Guangmao Shen, Yan Wu, Zan Zhang, Kun Qian   +6 more
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Therapeutic Potential of Berberine for Osteoporosis and its Underlying Mechanisms: A Bioinformatics, Network Pharmacology, Molecular Dynamics Simulation Study

Natural Product Communications, 2022
Osteoporosis is a systemic skeletal disease that can easily lead to bone fractures. Berberine has been shown to be effective in treating osteoporosis. This study was conducted to identify the potential mechanism of berberine in treating this complaint ...
Jin-Ling Yu, Bo-Wei Wang, Hui-Li Zhang, Liu-Qing Yang, Jing-Jing Yao, Han-Dan Huang, Lu Tao, Ying Gao, Zhi-Hui Liu   +8 more
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Berberine Induces Apoptosis in p53-Null Leukemia Cells by Down-Regulating XIAP at the Post-Transcriptional Level

Cellular Physiology and Biochemistry, 2013
Background: Berberine exerts anticancer activities both in vitro and in vivo through different mechanisms. However, the underlying molecular mechanisms of berberine induced p53-independent apoptosis remain unclear.
Jian Liu, Xiaoling Zhang, Aiguo Liu, Shuangyou Liu, Liuqing Zhang, Bei Wu, Qun Hu   +6 more
doaj   +1 more source