Formation and Conformation of Baicalin–Berberine and Wogonoside–Berberine Complexes [PDF]
Chemical and Pharmaceutical Bulletin, 2012 It is well-known that baicalin-berberine complex (1) precipitates in the water decoction of numerous Chinese Medicinal formulae containing Radix Scutellariae and Rhizoma Coptidis or Cortex Phellodendri. In the current study, ionic interaction between the carboxylate ion of baicalin and the quaternary ammonium ion of berberine was revealed to be ...
Jing-Rong, Wang +4 more
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Adenosine monophosphate-activated protein kinase activation is associated with suppression of NLRP3 inflammasome-mediated neuroinflammation in a weight-drop model of traumatic brain injury in Sprague-Dawley rats. [PDF]
Animal Model Exp MedThis graphical abstract illustrates the study's schematic model. Adenosine monophosphate–activated protein kinase (AMPK) activators exhibited neuroprotection in the weight‐drop model of traumatic brain injury by improving cognition and regulating oxidative stress, microglial activation, and nucleotide‐binding oligomerization domain, leucine‐rich repeat,
Kodi T +3 more
europepmc +2 more sources
Antidiabetic and antimicrobial activities of fractions and compounds isolated from Berberis brevissima Jafri and Berberis parkeriana Schneid [PDF]
, 2013 Methanol extracts of the roots of B. brevissima and B. parkeriana were examined for antidiabetic and antimicrobial activities. Six compounds i.e berberine, 8-oxo-berberine, dehydrocheilanthifoline, columbamine, jatrorrhizine and glutamic acid were ...
Shah, Syed Qaisar +9 more
core +4 more sources
Pharmaceutics, 2020 We aimed to develop a berberine formulation to enhance the intestinal absorption and plasma concentrations of berberine through the inhibition of P-glycoprotein (P-gp)-mediated efflux and the intestinal metabolism of berberine in rats.
Mihwa Kwon +5 more
doaj +1 more source
Pharmacokinetics and Excretion of Berberine and Its Nine Metabolites in Rats
Frontiers in Pharmacology, 2021 Berberine, a well-known alkaloid, has been proved to possess various pharmacological activities. Previous studies demonstrated that berberine could be extensively metabolized and the metabolites also contributed to its therapeutic effects.
Xinchi Feng +5 more
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Effects of Berberine on Atherosclerosis [PDF]
Frontiers in Pharmacology, 2021 Atherosclerosis is an epidemic across the globe[A1], and its morbidity and mortality remain high, involving various complications and poor prognoses. In atherosclerosis, endothelial cells (ECs) dysfunction, vascular smooth muscle cells (VSMCs) migration and proliferation, foam cell formation, and inflammatory cell recruitment contribute to disease ...
Rui Rui +6 more
openaire +3 more sources
Uptake of and Resistance to the Antibiotic Berberine by Individual Dormant, Germinating and Outgrowing Bacillus Spores as Monitored by Laser Tweezers Raman Spectroscopy. [PDF]
PLoS ONE, 2015 Berberine, an alkaloid originally extracted from the plant Coptis chinensis and other herb plants, has been used as a pharmacological substance for many years.
Shiwei Wang +4 more
doaj +1 more source
PLoS ONE, 2021 Berberine is a promising botanical pesticide against fungal plant pathogens. However, whether berberine inhibits the invasion of fungal pathogen across plant surface remains unclear.
Ying Li +4 more
doaj +1 more source
Berberine for the treatment of hypertension: a systematic review [PDF]
, 2021 BackgroundHypertension is the highest risk factor for disease globally. One popular therapy is berberine.MethodsThe review followed the protocol PRISMA-P, and is reported according to the related PRISMA statement.
Atherton, Iain, Suadoni, Marco Tullio
core +1 more source
Pharmacological Research, 2023 A potential role of berberine, a benzyl isoquinoline alkaloid, in cancer therapy is apparent. Its underlying mechanisms of berberine against breast carcinoma under hypoxia have not been elucidated.
Yanfang Sun +8 more
doaj +1 more source