Comparative study of antioxidant and antimicrobial activity of berberine-derived Schiff bases, nitro-berberine and amino-berberine [PDF]
Heliyon, 2023 In recent years, the scientific community has focused on traditional natural products and their potential therapeutic benefits. Berberine is a plant-derived isoquinoline alkaloid with a variety of biological properties and identified as a promising ...
Soheila Alipour Noghabi +3 more
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Enhanced Intestinal Absorption and Pharmacokinetic Modulation of Berberine and Its Metabolites through the Inhibition of P-Glycoprotein and Intestinal Metabolism in Rats Using a Berberine Mixed Micelle Formulation [PDF]
Pharmaceutics, 2020 We aimed to develop a berberine formulation to enhance the intestinal absorption and plasma concentrations of berberine through the inhibition of P-glycoprotein (P-gp)-mediated efflux and the intestinal metabolism of berberine in rats.
Mihwa Kwon +2 more
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Berberine enhances cisplatin efficacy in ehrlich ascites carcinoma via modulation of apoptotic pathway and efferocytosis [PDF]
Scientific ReportsBerberine, a bio-alkaloid from medicinal plants, shows therapeutic potential against various ailments, including cancer. This study evaluated berberine’s effects on the PI3K/Akt pathway and efferocytosis in an adenocarcinoma model to reduce cisplatin ...
Maha M. Salem +4 more
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Molecular and Crystal Structures of Three Berberine Derivatives [PDF]
Molecules, 2001 Berberine azide, berberine thiocyanate, and 8-cyano-8H-berberine were prepared from berberine chloride, a quaternary protoberberine alkaloid. The molecular and crystal structures of all compounds are reported and discussed.
JiřàDostál +4 more
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Effects and mechanisms of berberine in diabetes treatment
Acta Pharmaceutica Sinica B, 2012 Berberine from Rhizoma Coptidis is an oral hypoglycemic agent with anti-dyslipidemia and anti-obesity activities. Its metabolic activity of regulating blood glucose and lipids has been widely studied and evidenced in patients and various animal models ...
Jun Yin, Jianping Ye, Weiping Jia
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Formation and Conformation of Baicalin–Berberine and Wogonoside–Berberine Complexes [PDF]
Chemical and Pharmaceutical Bulletin, 2012 It is well-known that baicalin-berberine complex (1) precipitates in the water decoction of numerous Chinese Medicinal formulae containing Radix Scutellariae and Rhizoma Coptidis or Cortex Phellodendri. In the current study, ionic interaction between the carboxylate ion of baicalin and the quaternary ammonium ion of berberine was revealed to be ...
Jing-Rong, Wang +4 more
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Evaluation of the Potential Role of Silver Nanoparticles Loaded with Berberine in Improving Anti-Tumor Efficiency [PDF]
Pharmaceutical Sciences, 2022 Background: Cancer is a progressive disease, its incidence and death rates are rapidly increasing globally. Numerous adverse effects are associated with the available interventions. Hence, the current study was undertaken to explore the anticancer effect
Mohamed Othman +6 more
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Frontiers in Pharmacology, 2022 Lysyl hydroxylase-2 (LH2) involves in the hydroxylation of telopeptide lysine residues during collagen deposition. Recent studies indicate that interleukin (IL)-6 generated by the chronic inflammation disease may trigger the LH2 expression to accelerate ...
Yishan Du +9 more
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Pharmaceutical Biology, 2022 Context Berberine has myocardial protective effects.Objectives The protective effects of berberine on heart ischemia–reperfusion (I/R) injury were explored.Materials and methods Human cardiomyocytes were divided into control group, oxygen-glucose ...
Xiaojing Jia, Wei Shao, Suqing Tian
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Berberine induces caspase-independent cell death in colon tumor cells through activation of apoptosis-inducing factor. [PDF]
PLoS ONE, 2012 Berberine, an isoquinoline alkaloid derived from plants, is a traditional medicine for treating bacterial diarrhea and intestinal parasite infections. Although berberine has recently been shown to suppress growth of several tumor cell lines, information ...
Lihong Wang +10 more
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