Results 41 to 50 of about 39,868 (244)

Berberine Inhibits the Release of Glutamate in Nerve Terminals from Rat Cerebral Cortex. [PDF]

PLoS ONE, 2013
Berberine, an isoquinoline plant alkaloid, protects neurons against neurotoxicity. An excessive release of glutamate is considered to be one of the molecular mechanisms of neuronal damage in several neurological diseases.
Tzu-Yu Lin, Yu-Wan Lin, Cheng-Wei Lu, Shu-Kuei Huang, Su-Jane Wang   +4 more
doaj   +1 more source

Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells [PDF]

, 2014
The insulin/IGF-1 (insulin-like growth factor 1)-activated protein kinase Akt (also known as protein kinase B) phosphorylates Ser(487) in the ‘ST loop’ (serine/threonine-rich loop) within the C-terminal domain of AMPK-α1 (AMP-activated protein kinase-α1),
Chen, Cross, D. Grahame Hardie, Dagon, Dale, Davidson, Davies, Davies, Decensi, Evans, Faubert, Fiona A. Ross, Fogarty, Frame, Goransson, Gowans, Graeme J. Gowans, Hardie, Hawley, Hawley, Hawley, Hawley, Hawley, Hawley, Hirai, Horman, Hurley, Hurley, Ji, Lee, Lizcano, Mankouri, Nicholas R. Leslie, Ning, Obata, Obenauer, Priyanka Tibarewal, Roach, Sanchez-Cespedes, Sanders, Scott, Shaw, Simon A. Hawley, Street, Suzuki, Towler, Wingo, Woods, Woods, Woods, Woods, Xiao, Xiao, Yuan   +53 more
core   +4 more sources

Berberine: A Promising Treatment for Neurodegenerative Diseases

Frontiers in Pharmacology, 2022
Berberine, as a natural alkaloid compound, is characterized by a diversity of pharmacological effects. In recent years, many researches focused on the role of berberine in central nervous system diseases.
Ziqian Cheng, Chenglan Kang, Songtian Che, Jingyun Su, Qihan Sun, Tongtong Ge, Yi Guo, Jiayin Lv, Zhihui Sun, Wei Yang, Bingjin Li, Xin Li, Ranji Cui   +12 more
doaj   +1 more source

Phytochemical Compounds and Protection from Cardiovascular Diseasesa. A State of the Art [PDF]

, 2015
Cardiovascular diseases represent a worldwide relevant socioeconomical problem. Cardiovascular disease prevention relies also on lifestyle changes, including dietary habits.
PAGLIARO, BENIAMINO ROSARIO, RUBATTU, Speranza Donatella, SANTOLAMAZZA, CATERINA, SIMONELLI, FRANCESCA   +3 more
core   +4 more sources

Therapeutic Potential of Berberine for Osteoporosis and its Underlying Mechanisms: A Bioinformatics, Network Pharmacology, Molecular Dynamics Simulation Study

Natural Product Communications, 2022
Osteoporosis is a systemic skeletal disease that can easily lead to bone fractures. Berberine has been shown to be effective in treating osteoporosis. This study was conducted to identify the potential mechanism of berberine in treating this complaint ...
Jin-Ling Yu, Bo-Wei Wang, Hui-Li Zhang, Liu-Qing Yang, Jing-Jing Yao, Han-Dan Huang, Lu Tao, Ying Gao, Zhi-Hui Liu   +8 more
doaj   +1 more source

Isolation, Identification, Modification, and Biological Analysis of extracts of A. Mexicana [PDF]

, 2020
Argemone mexicana is a member of the Papaveraceae family of plants that has been used for centuries in traditional medicine by indigenous communities in Mexico and the United States.
Lefeber, Theodore, Orozco-Nunnelly, Danielle, Pruet, Jeffrey, Villegas, Jessica   +3 more
core   +1 more source

The full repertoire of Drosophila gustatory receptors for detecting an aversive compound. [PDF]

, 2015
The ability to detect toxic compounds in foods is essential for animal survival. However, the minimal subunit composition of gustatory receptors required for sensing aversive chemicals in Drosophila is unknown.
Jeong, Yong Taek, Kim, Yonjung, Lee, Min Goo, Lee, Youngseok, Montell, Craig, Moon, Seok Jun, Shim, Jaewon   +6 more
core   +2 more sources

Preparation of Berberine@carbon Dots Nano-Formulation: Synthesis, Characterization and Herbicidal Activity against Echinochloa crus-galli and Amaranthus retroflexus Two Common Species of Weed

Nanomaterials, 2022
Berberine (Ber) is easy to synthesize and has a variety of biological and pharmacological activities. At present, the existing studies on berberine have focused predominantly on its antibacterial activity; its herbicidal activity is rarely reported.
Junhu Xu, Shuang Rong, Ziqi Qin, Guangmao Shen, Yan Wu, Zan Zhang, Kun Qian   +6 more
doaj   +1 more source

Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: The cellular mechanism [PDF]

, 2010
Extensive studies have revealed that berberine, a small molecule derived from Coptidis rhizoma (Huanglian in Chinese) and many other plants, has strong anti-tumor properties. To better understand berberine-induced cell death and its underlying mechanisms
Feng, Y, Man, K, Tong, Y, Tsang, CM, Tsao, SW, Wang, N, Zhu, M   +6 more
core   +1 more source

Berberine Induces Apoptosis in p53-Null Leukemia Cells by Down-Regulating XIAP at the Post-Transcriptional Level

Cellular Physiology and Biochemistry, 2013
Background: Berberine exerts anticancer activities both in vitro and in vivo through different mechanisms. However, the underlying molecular mechanisms of berberine induced p53-independent apoptosis remain unclear.
Jian Liu, Xiaoling Zhang, Aiguo Liu, Shuangyou Liu, Liuqing Zhang, Bei Wu, Qun Hu   +6 more
doaj   +1 more source