Results 61 to 70 of about 26,756 (250)

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu   +5 more
wiley   +1 more source

The Effects of Berberine and Nitroxl (HNO) on the Glucose Uptake in L929 Fibroblast Cells [PDF]

open access: yes, 2012
Berberine, which has a long history of use in Chinese medicine, has recently been shown to have efficacy in the treatment of diabetes. While the hypoglycemic effect of berberine has been clearly documented in animal and cell line models, such as 3T3-L1 ...
Chenge, Jude Terver-Jeremiah
core   +1 more source

In Vitro Anti- Activity of Berberine and Barberry Extracts: A Preliminary Report

open access: yesNatural Product Communications, 2019
The berberine accumulation in Berberis vulgaris and antibacterial activity of plant extracts against Helicobacter pylori were examined. The antibacterial activities of berberine, the main alkaloid of B.
Branislava D. Kocić   +5 more
doaj   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

open access: yesAdvanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai   +7 more
wiley   +1 more source

A Metal‐Phenolic Nanocluster Orchestrates Mito‐Ca2+ Metabolic Autonomy for Tumor Ca2+ Interference Therapy

open access: yesAdvanced Science, EarlyView.
Tumor Ca2+ interference therapy suffers from self‐protective Ca2+ metabolic autoregulation. In this scenario, a versatile metal‐phenolic nanocluster (TCMH) is engineered to modulate mitochondrial calcium uniporter (MCU) ‐mediated mito‐Ca2+ metabolic autonomy.
Ronglong Chen   +13 more
wiley   +1 more source

Isolation and Characterization of the Genes Involved in the Berberine Synthesis Pathway in Asian Blue Cohosh, Caulophyllum robustum

open access: yesPlants, 2023
Caulophyllum robustum, commonly named Asian blue cohosh, is a perennial herb in the family Berberidaceae. It has traditionally been used for folk medicine in China. We isolated berberine from the leaves, stem, roots, and fruits of C.
Nam-Il Park   +13 more
doaj   +1 more source

Microenvironment‐Responsive Nanomedicine Enables Vertical Modulation of Mitochondrial Pathological Networks in Myocardial Ischemia–Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
A mitochondria‐targeted, microenvironment‐responsive nanoplatform enables pH/ROS‐triggered co‐delivery of berberine and isoliensinine to orchestrate ROS scavenging, inflammation suppression, and apoptosis inhibition. This vertical modulation of mitochondrial pathological networks preserves mitochondrial function and effectively mitigates myocardial ...
Jue Wang   +11 more
wiley   +1 more source

Berberine-INF55 (5-nitro-2-phenylindole) hybrid antimicrobials: effects of varying the relative orientation of the berberine and INF55 components [PDF]

open access: yes, 2010
Hybrid antimicrobials containing an antibacterial linked to a multidrug resistance (MDR) pump inhibitor make up a promising new class of agents for countering efflux-mediated bacterial drug resistance.
Danuta Tomkiewicz (20241213)   +8 more
core  

Growth-suppressive effect of berberine on endometrial carcinoma cells: Role of mitochondrial and PI3K/Akt pathway [PDF]

open access: yes, 2016
Berberine is an isoquinoline alkaloid and a popular dietary supplement in the US market for lowering blood glucose and managing a healthy lipid profile. The anti-tumour activity of berberine is also known. Endometrial cancer is a gynecological malignancy
Han-Peng Kuo; Yi-Jen Lee; Chih-Yu Hsu; Shou-Lun Lee; Shih-Chung Hsu; Tzu-Chao Chuange; Jah-Yao Liuf; Chao-Lin Kuo; Chi-Tang Ho; Ming-Ching Kao
core   +1 more source

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