Results 21 to 30 of about 28,872 (258)

Berberine: a comprehensive Approach to combat human maladies

International Journal of Food Properties, 2023
Berberine is a metabolite of many medicinal plants. Chemically, berberine belongs to the isoquinoline alkaloids family. The roots of plants grown at lower elevations have a higher concentration of berberine as compared to plants grown at higher ...
Zarina Mushtaq, Muhammad Imran, Farhan Saeed, Ali Imran, Shinawar Waseem Ali, Muhammad Shahbaz, Suliman A. Alsagaby, Yolanda Guerrero Sánchez, Maryam Umar, Muzzamal Hussain, Waleed Al Abdulmonem, Entessar Al Jbawi, Mahwish, Ahmed H. El-Ghorab, Mohamed A. Abdelgawad   +14 more
doaj   +1 more source

Berberine and palmatine inhibit the growth of human rhabdomyosarcoma cells [PDF]

, 2019
Published online: 29 Aug 2019A natural isoquinoline alkaloid, berberine, has been known to exhibit anti-tumor activity in various cancer cells via inducing cell cycle arrest. However, it has not been investigated whether berberine and its analogs inhibit
Nakamura, Shunichi, Shinji, Sayaka, Umezawa, Koji, Takaya, Tomohide, Nihashi, Yuma   +4 more
core   +1 more source

Berberine Reduces Lipid Accumulation by Promoting Fatty Acid Oxidation in Renal Tubular Epithelial Cells of the Diabetic Kidney

Frontiers in Pharmacology, 2022
Abnormal lipid metabolism in renal tubular epithelial cells contributes to renal lipid accumulation and disturbed mitochondrial bioenergetics which are important in diabetic kidney disease.
Qingfeng Rong, Baosheng Han, Yafeng Li, Yafeng Li, Haizhen Yin, Jing Li, Yanjuan Hou   +6 more
doaj   +1 more source

In Vivo and in Vitro Study on Drug-Drug Interaction of Lovastatin and Berberine from Pharmacokinetic and HepG2 Cell Metabolism Studies

Molecules, 2016
Background: We assumed that the pharmacokinetics of lovastatin could be changed by the induction effect of berberine. Methods: An UPLC-MS/MS method was developed and validated for the pharmacokinetics tudy of lovastatin to investigate the in vivo drug ...
Hanming Cui, Jialong Wang, Qiuyan Zhang, Mengmeng Dang, Hui Liu, Yu Dong, Lu Zhang, Fang Yang, Jianhua Wu, Xiaolin Tong   +9 more
doaj   +1 more source

Genetic evidence for inhibition of bacterial division protein FtsZ by berberine. [PDF]

PLoS ONE, 2010
BACKGROUND: Berberine is a plant alkaloid that is widely used as an anti-infective in traditional medicine. Escherichia coli exposed to berberine form filaments, suggesting an antibacterial mechanism that involves inhibition of cell division.
Jaroslaw M Boberek, Jem Stach, Liam Good
doaj   +1 more source

RETRACTED: Berberine Suppresses Stemness and Tumorigenicity of Colorectal Cancer Stem-Like Cells by Inhibiting m6A Methylation

Frontiers in Oncology, 2021
BackgroundCancer stem cells (CSCs) are able to survive after cancer therapies, resulting in tumor progression and recurrence, as is seen in colorectal cancer.
Ziyi Zhao, Ziyi Zhao, Jinhao Zeng, Jinhao Zeng, Qiang Guo, Kunming Pu, Yi Yang, Nianzhi Chen, Gang Zhang, Maoyuan Zhao, Qiao Zheng, Jianyuan Tang, Jianyuan Tang, Qiongying Hu   +13 more
doaj   +1 more source

Berberine for prevention of dementia associated with diabetes and its comorbidities: A systematic review [PDF]

, 2020
Background A growing number of epidemiological studies indicate that metabolic syndrome (MetS) and its associated features play a key role in the development of certain degenerative brain disorders, including Alzheimer’s disease and vascular dementia ...
Katsuno, T., Shinjyo, N., Parkinson, J., Bell, J.D., Bligh, S.W.A.   +4 more
core   +1 more source

Preparation and Evaluation of Antidiabetic Agents of Berberine Organic Acid Salts for Enhancing the Bioavailability

Molecules, 2018
Berberine has many pharmacological effects, such as antidiabetic, antimicrobial, anti-inflammatory, and antioxidant, but the question remains on how its low oral bioavailability has greatly limited its clinical application. As a safer hypoglycemic agent,
Hong-Xin Cui, Ya-Nan Hu, Jing-Wan Li, Ke Yuan, Ying Guo   +4 more
doaj   +1 more source

Activation of AMP-activated protein kinase is required for berberine-induced reduction of atherosclerosis in mice: the role of uncoupling protein 2. [PDF]

PLoS ONE, 2011
Berberine, a botanical alkaloid purified from Coptidis rhizoma, is reported to activate the AMP-activated protein kinase (AMPK). Whether AMPK is required for the protective effects of berberine in cardiovascular diseases remains unknown.
Qilong Wang, Miao Zhang, Bin Liang, Najeeb Shirwany, Yi Zhu, Ming-Hui Zou   +5 more
doaj   +1 more source

Antiviral activity of berberine [PDF]

Archives of Virology, 2020
AbstractPlants are a rich source of new antiviral, pharmacologically active agents. The naturally occurring plant alkaloid berberine (BBR) is one of the phytochemicals with a broad range of biological activity, including anticancer, anti-inflammatory and antiviral activity.
Alicja Warowicka, Robert Nawrot, Anna Goździcka-Józefiak   +2 more
openaire   +2 more sources