Results 21 to 30 of about 26,756 (250)
Crystal Growth & Design, 2016 Berberine is a drug with an intense bitter taste. The high aqueous solubility of its chloride salt, which is commonly used in commercial drug products of berberine, worsens the challenge of taste masking.
Chenguang Wang +4 more
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EXCLI Journal : Experimental and Clinical Sciences, 2022 Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a secreted protein and a critical regulator of low-density lipoprotein-cholesterol (LDL-C) through inducing degradation of the LDL receptor (LDLR) within the hepatocyte lysosome. PCSK9 deficiency significantly improves the survival rate of cardiovascular disease (CVDs) patients.
Sarina Ataei +2 more
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Frontiers in Pharmacology, 2023 Berberine is an isoquinoline alkaloid found in plants. It presents a wide range of pharmacological activities, including anti-inflammatory and antioxidant properties, despite a low oral bioavailability.
Tessa Dehau +5 more
doaj +1 more source
Frontiers in Immunology, 2021 Berberine, which is a traditional Chinese medicine can inhibit tumorigenesis by inducing tumor cell apoptosis. However, the immunoregulatory of effects berberine on T cells remains poorly understood.
Yunhan Ma +12 more
doaj +1 more source
Redox regulation of the AMP-activated protein kinase. [PDF]
PLoS ONE, 2010 Redox state is a critical determinant of cell function, and any major imbalances can cause severe damage or death.The aim of this study is to determine if AMP-activated protein kinase (AMPK), a cellular energy sensor, is activated by oxidants generated ...
Yingying Han +4 more
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Pharmacokinetics and Excretion of Berberine and Its Nine Metabolites in Rats
Frontiers in Pharmacology, 2021 Berberine, a well-known alkaloid, has been proved to possess various pharmacological activities. Previous studies demonstrated that berberine could be extensively metabolized and the metabolites also contributed to its therapeutic effects.
Xinchi Feng +5 more
doaj +1 more source
Effects of Berberine on Atherosclerosis [PDF]
Frontiers in Pharmacology, 2021 Atherosclerosis is an epidemic across the globe[A1], and its morbidity and mortality remain high, involving various complications and poor prognoses. In atherosclerosis, endothelial cells (ECs) dysfunction, vascular smooth muscle cells (VSMCs) migration and proliferation, foam cell formation, and inflammatory cell recruitment contribute to disease ...
Rui Rui +6 more
openaire +3 more sources
Uptake of and Resistance to the Antibiotic Berberine by Individual Dormant, Germinating and Outgrowing Bacillus Spores as Monitored by Laser Tweezers Raman Spectroscopy. [PDF]
PLoS ONE, 2015 Berberine, an alkaloid originally extracted from the plant Coptis chinensis and other herb plants, has been used as a pharmacological substance for many years.
Shiwei Wang +4 more
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Berberine for the treatment of hypertension: a systematic review [PDF]
, 2021 BackgroundHypertension is the highest risk factor for disease globally. One popular therapy is berberine.MethodsThe review followed the protocol PRISMA-P, and is reported according to the related PRISMA statement.
Atherton, Iain, Suadoni, Marco Tullio
core +2 more sources
Berberine: a comprehensive Approach to combat human maladies
International Journal of Food Properties, 2023 Berberine is a metabolite of many medicinal plants. Chemically, berberine belongs to the isoquinoline alkaloids family. The roots of plants grown at lower elevations have a higher concentration of berberine as compared to plants grown at higher ...
Zarina Mushtaq +14 more
doaj +1 more source