Results 271 to 280 of about 896,426 (307)

Potent beta-amyloid modulators.

Neuro-degenerative diseases, 2008
Currently, the potential to interfere with the pathology of beta-amyloid targeting a well-known drugable enzyme, the acetylcholinesterase (AChE), is opened. Peripheral or dual binding site inhibitors of AChE may simultaneously alleviate the cognitive and behavioral deficits in Alzheimer's disease (AD) patients and, more importantly, act as disease ...
E, García-Palomero, P, Muñoz, P, Usan, P, Garcia, E, Delgado, C, De Austria, R, Valenzuela, L, Rubio, M, Medina, A, Martínez   +9 more
openaire   +1 more source

Beta amyloid resurrected

Nature, 1991
Alan F. Wright, Michel Goedert, Nicholas D. Hastie   +2 more
openaire   +1 more source

Beta Amyloid

2010
Peter J. Tyrer, Mark Slifstein, Joris C. Verster, Kim Fromme, Amee B. Patel, Britta Hahn, Christer Allgulander, A. Claudio Cuello, Giovanni Hernandez, Peter Shizgal, Irwin Lucki, Warren K. Bickel, Darren R. Christensen, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Verity J. Brown, David S. Tait, Andrea Bari, Gorkem Yararbas, Sakire Pogun, Richard W. Foltin, Harriet de Wit, Daniel Hoyer, Daniel Hoyer, Christer Allgulander, David Nutt, Peter J. Tyrer, Gessica Sala, Lucio Tremolizzo, Carlo Ferrarese, Mark Slifstein, Eric P. Zorrilla, Pietro Cottone, Sarah Parylak, Gorkem Yararbas, Sakire Pogun, Anne M. Andrews, Greg A. Gerhardt, Lynette C. Daws, R. H. Belmaker, Tiffany Thomas, Robert L. Findling, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Helen J. Cassaday, Seiya Miyamoto, Jean-Michel Scherrmann, Jean-Michel Scherrmann, Michael J. Owens, Chase H. Bourke, Martina de Zwaan, Christof Baltes, Thomas Mueggler, Markus Rudin, Mark Slifstein, Mark Slifstein, Debby Van Dam, Peter Paul De Deyn, Joseph H. Friedman, Wiepke Cahn, Heleen B. M. Boos, H. D. Postma, David S. Middlemas, David B. Bylund, Giovanni Hernandez, Peter Shizgal, David C. S. Roberts, Emma Childs, Daniel Hoyer, Seiya Miyamoto, Naheed (Max) Mirza, Lance R. McMahon, Linda Dykstra, Gabriele Fischer, Annemarie Unger, Mohammed Shoaib, David S. Baldwin, W. Wolfgang Fleischhacker   +81 more
openaire   +1 more source

beta-amyloid: friend or foe.

Medical hypotheses, 2001
The function of the amyloid precursor protein (APP) and its product, beta-amyloid, (Abeta) is at present unknown. The deposition of Abeta in senile plaques as well as meningeal and cerebral vessels has led many researchers to discount the possibility of a beneficial protective function for the protein.
openaire   +1 more source

Mapping brain beta-amyloid.

Current opinion in neurology, 2009
This article reviews recent developments in the field of amyloid imaging using PET, specifically the ability to quantify the amount and distribution of brain beta-amyloid, the protein that occupies a central position in leading theories of the pathogenesis of Alzheimer's disease.Several imaging-disorder correlations place the technique itself on a ...
openaire   +1 more source

Review on Alzheimer's disease: Inhibition of amyloid beta and tau tangle formation

International Journal of Biological Macromolecules, 2021
Hossein Ashrafian, Rizwan Hasan Khan
exaly  

The role of amyloid-beta in the regulation of memory

Biochemical Pharmacology, 2014
John E Morley, Susan A Farr
exaly  

P1–244: Validation of beta‐amyloid test as a reliable tool for quantifying beta‐amyloid 1–40 and beta‐amyloid 1–42 in blood

Alzheimer's & Dementia, 2013
Virginia Pérez, Noelia Fandos, Pedro Pesini, Manuel Sarasa   +3 more
openaire   +1 more source

Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis

Diabetologia, 2009
S Zraika, R L Hull, Robert Kisilevsky
exaly  

Beta Amyloid

2008
openaire   +1 more source