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Raab MS, Breitkreutz I, Tonon G, et al. Targeting PKC: a novel role for beta-catenin in ER stress and apoptotic signaling. Blood. 2009;113(7):1513-1521.

Blood
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Wnt/beta-Catenin Signaling in Glioma

Journal of NeuroImmune Pharmacology, 2012
Extensive data have shown that Wnt/beta-catenin signaling is associated with various disease pathologies, including an important role in tumorigenesis. Here, we review the regulation of Wnt/beta-catenin signaling in glioma, with particular focus on the expression signatures of the main components in Wnt/beta-catenin signaling, the role of key factors ...
Chunsheng Kang, Kailiang Zhang, Peiyu Pu   +2 more
exaly   +3 more sources

beta-catenin expression in pilomatrixomas. Relationship with beta-catenin gene mutations and comparison with beta-catenin expression in normal hair follicles

British Journal of Dermatology, 2001
beta-catenin functions in signal transduction in the Wnt signalling pathway, which has recently been implicated in hair follicle (HF) morphogenesis. beta-catenin gene mutations affecting exon 3 have been reported in a high percentage of human pilomatrixomas.
G, Moreno-Bueno, C, Gamallo, L, Pérez-Gallego, F, Contreras, J, Palacios   +4 more
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The WNT/Beta-catenin pathway in melanoma

Frontiers in Bioscience, 2006
The Wnt/beta-catenin pathway is involved in various cellular activities--including determination, proliferation, migration and differentiation--in embryonic development and adult homeostasis. The deregulation or constitutive activation of the Wnt/beta-catenin pathway may lead to cancer formation.
Lionel, Larue, Véronique, Delmas
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Beta‐catenin and axis formation in planarians

BioEssays, 2009
AbstractIn three recent articles it was shown that β‐catenin is crucial for the establishment and the maintenance of the overall polarity and especially for the character ‘posterior’ in planarians. If the transcription of the β‐catenin gene was silenced by RNA interference, the overall polarity is lost, and in regenerating fragments a posterior ...
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p35/cdk5 binds and phosphorylates beta-catenin and regulates beta-catenin/presenilin-1 interaction

European Journal of Neuroscience, 2001
The neuronal cyclin-dependent kinase p35/cdk5 comprises a catalytic subunit (cdk5) and an activator subunit (p35). To identify novel p35/cdk5 substrates, we utilized the yeast two-hybrid system to screen for human p35 binding partners. From one such screen, we identified beta-catenin as an interacting protein.
Kesavapany, S, Lau, K F, McLoughlin, D M, Brownlees, J, Ackerley, S, Leigh, P N, Shaw, C E, Miller, C C J   +7 more
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IKK and (Beta)-Catenin in Breast Cancer

2002
Abstract : The wnt signaling pathway activates oncogene, beta-catenin. It associates with an APC, GSK-3b and axin complex which targets it for phosphorylation and ubiquitin-mediated degradation. NFkB transcription factor is associated with inhibitory IkBa.
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Beta-Catenin and the Survival of Hepatocytes

2017
The Wnt/β-catenin pathway is critical for liver development, differentiation, metabolism, and homeostasis. Aberrations in this pathway have also been identified in many pathophysiological conditions, such as nonalcoholic steatohepatitis, fibrosis, and hepatobiliary neoplasias.
Kari Nichole Nejak-Bowen, Satdarshan Pal Singh Monga   +1 more
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PML is a target gene of beta-catenin and plakoglobin, and coactivates beta-catenin-mediated transcription.

Cancer research, 2002
beta-Catenin and its close homologue plakoglobin (gamma-catenin) are major constituents of submembranal cell-cell adhesion sites. In addition, beta-catenin is a key component in the canonical Wnt pathway. Aberrantly activated beta-catenin signaling contributes to cancer progression by inducing [in complex with lymphocyte enhancer factor (LEF)/T-cell ...
Michael, Shtutman, Jacob, Zhurinsky, Moshe, Oren, Elina, Levina, Avri, Ben-Ze'ev   +4 more
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