Results 221 to 230 of about 86,249 (262)
Some of the next articles are maybe not open access.
HIF-2alpha enhances beta-catenin/TCF-driven transcription by interacting with beta-catenin.
Cancer research, 2011The tumor-promoting factors β-catenin and hypoxia-inducible factor (HIF) are often found to be coactivated in rapidly growing tumors. Recently, it was shown that HIF-1α negatively regulates Wnt/β-catenin signaling by sequestering β-catenin from β-catenin/T-cell factor (TCF).
Hyunsung, Choi +3 more
openaire +1 more source
Proteininteraktionspartner von beta-Catenin
2004Titelblatt 1 Einleitung 1.1 PDZ-Proteine und Signaltransduktion 1.2 Der Wnt-Signaltransduktionsweg 1.3 Bcr: negativer Regulator der pathogenen Effekte von Bcr-Abl 2 Leitfaden dieser Arbeit 3 Material und Methoden 3.1 Material 3.2 Methoden 4 Ergebnisse 4.1 Identifikation von PDZ-abhängigen Proteininteraktionen 4.2 PDZ-Protein Erbin, Interaktionspartner ...
openaire +1 more source
Signal transduction of beta-catenin.
Current opinion in cell biology, 1996Beta-catenin participates in signal transduction and developmental patterning in Xenopus and Drosophila embryos as a component of the Wnt signaling pathway. Its signaling activity is distinct from its role in cadherin-mediated cell adhesion, and it probably acts either in the cytosol or in the nucleus.
openaire +1 more source
Cytokine & growth factor reviews, 2000
The Wnt/Wingless signaling transduction pathway plays an important role in both embryonic development and tumorigenesis. beta-Catenin, a key component of the Wnt signaling pathway, interacts with the TCF/LEF family of transcription factors and activates transcription of Wnt target genes.
openaire +1 more source
The Wnt/Wingless signaling transduction pathway plays an important role in both embryonic development and tumorigenesis. beta-Catenin, a key component of the Wnt signaling pathway, interacts with the TCF/LEF family of transcription factors and activates transcription of Wnt target genes.
openaire +1 more source
Nihon rinsho. Japanese journal of clinical medicine, 2002
K, Ogawa, Y, Yaginuma
openaire +1 more source
K, Ogawa, Y, Yaginuma
openaire +1 more source
Gan to kagaku ryoho. Cancer & chemotherapy, 1997
The APC gene is mutated in the majority of colorectal tumors. The product of this gene is a 300 kDa protein associated with beta-catenin and the human homolog of the Drosophila tumor suppressor DLG. The study of the function of APC provides important insights into the mechanisms of the development of colorectal tumor.
openaire +1 more source
The APC gene is mutated in the majority of colorectal tumors. The product of this gene is a 300 kDa protein associated with beta-catenin and the human homolog of the Drosophila tumor suppressor DLG. The study of the function of APC provides important insights into the mechanisms of the development of colorectal tumor.
openaire +1 more source